8TTJ
 
 | | Tryptophan-6-halogenase BorH complexed with 6-chlorotryptophan | | Descriptor: | 6-CHLORO-L-TRYPTOPHAN, SULFATE ION, Tryptophan 6-halogenase | | Authors: | Lingkon, K, Bellizzi, J.J. | | Deposit date: | 2023-08-14 | | Release date: | 2023-08-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Crystallographic and thermodynamic evidence of negative cooperativity of flavin and tryptophan binding in the flavin-dependent halogenases AbeH and BorH.
Biorxiv, 2023
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8TTI
 | | Trp-6-Halogenase BorH complexed with FAD and Trp | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, TRYPTOPHAN, ... | | Authors: | Lingkon, K, Bellizzi, J.J. | | Deposit date: | 2023-08-14 | | Release date: | 2023-08-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Crystallographic and thermodynamic evidence of negative cooperativity of flavin and tryptophan binding in the flavin-dependent halogenases AbeH and BorH.
Biorxiv, 2023
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8TTK
 | | Tryptophan-6-halogenase BorH apo structure | | Descriptor: | SULFATE ION, Tryptophan 6-halogenase | | Authors: | Lingkon, K, Bellizzi, J.J. | | Deposit date: | 2023-08-14 | | Release date: | 2023-08-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Crystallographic and thermodynamic evidence of negative cooperativity of flavin and tryptophan binding in the flavin-dependent halogenases AbeH and BorH.
Biorxiv, 2023
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2MR7
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3G1P
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1HKH
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1HL7
 | | Gamma lactamase from an Aureobacterium species in complex with 3a,4,7,7a-tetrahydro-benzo [1,3] dioxol-2-one | | Descriptor: | 3A,4,7,7A-TETRAHYDRO-BENZO [1,3] DIOXOL-2-ONE, GAMMA LACTAMASE | | Authors: | Line, K, Isupov, M.N, Littlechild, J.A. | | Deposit date: | 2003-03-14 | | Release date: | 2004-03-30 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | The Crystal Structure of a (-)Gamma-Lactamase from an Aureobacterium Species Reveals a Tetrahedral Intermediate in the Active Site
J.Mol.Biol., 338, 2004
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2VIM
 | | X-ray structure of Fasciola hepatica thioredoxin | | Descriptor: | THIOREDOXIN | | Authors: | Line, K, Isupov, M.N, Garcia-Rodriguez, E, Maggioli, G, Parra, F, Littlechild, J.A. | | Deposit date: | 2007-12-05 | | Release date: | 2008-07-29 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.38 Å) | | Cite: | The Fasciola Hepatica Thioredoxin: High Resolution Structure Reveals Two Oxidation States.
Mol.Biochem.Parasitol., 161, 2008
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2WRT
 | | The 2.4 Angstrom structure of the Fasciola hepatica mu class GST, GST26 | | Descriptor: | CHLORIDE ION, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME 51 | | Authors: | Line, K, Isupov, M.N, LaCourse, E.J, Brophy, P.M, Littlechild, J.A. | | Deposit date: | 2009-09-02 | | Release date: | 2010-09-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The 2.5 Angstrom Structure of a Mu Class Gst from Fasciola Hepatica
To be Published
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2WB9
 | | Fasciola hepatica sigma class GST | | Descriptor: | BROMIDE ION, CYSTEINE, GLUTATHIONE, ... | | Authors: | Line, K, Isupov, M.N, LaCourse, J, Brophy, P.M, Littlechild, J.A. | | Deposit date: | 2009-02-23 | | Release date: | 2010-03-31 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | The 1.6 Angstrom Crystal Structure of the Fasciola Hepatica Sigma Class Gst
To be Published
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2WDU
 | | Fasciola hepatica sigma class GST | | Descriptor: | BROMIDE ION, DIMETHYL SULFOXIDE, GLUTATHIONE, ... | | Authors: | Line, K, Isupov, M.N, LaCourse, E.J, Brophy, P.M, Littlechild, J.A. | | Deposit date: | 2009-03-26 | | Release date: | 2010-04-21 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | The 1.6 Angstrom Crystal Structure of the Fasciola Hepatica Sigma Class Gst
To be Published
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2WS2
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3VAX
 | | Crystal structure of DndA from streptomyces lividans | | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, Putative uncharacterized protein dndA | | Authors: | Zhang, Z, Chen, F, Lin, K, Wu, G. | | Deposit date: | 2011-12-30 | | Release date: | 2013-01-02 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the cysteine desulfurase DndA from Streptomyces lividans which is involved in DNA phosphorothioation
Plos One, 7, 2012
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5XQZ
 | | Structure of the MOB1-NDR2 complex | | Descriptor: | GLYCEROL, MOB kinase activator 1A, Serine/threonine-protein kinase 38-like, ... | | Authors: | Wu, G, Lin, K. | | Deposit date: | 2017-06-07 | | Release date: | 2018-08-29 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control.
Nat Commun, 8, 2017
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7ED5
 | | A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase | | Descriptor: | MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ... | | Authors: | Shannon, A, Fattorini, V, Sama, B, Selisko, B, Feracci, M, Falcou, C, Gauffre, P, El Kazzi, P, Delpal, A, Decroly, E, Alvarez, K, Eydoux, C, Guillemot, J.-C, Moussa, A, Good, S, Colla, P, Lin, K, Sommadossi, J.-P, Zhu, Y.X, Yan, X.D, Shi, H, Ferron, F, Canard, B. | | Deposit date: | 2021-03-15 | | Release date: | 2022-02-16 | | Last modified: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase.
Nat Commun, 13, 2022
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7ZF2
 | | Protomeric substructure from an octameric assembly of M. tuberculosis RNA polymerase in complex with sigma-b initiation factor | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Trapani, S, Bron, P, Lai Kee Him, J, Brodolin, K, Morichaud, Z, Vishwakarma, R. | | Deposit date: | 2022-03-31 | | Release date: | 2023-02-08 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.86 Å) | | Cite: | Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization.
Nat Commun, 14, 2023
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3LR2
 | | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Major ampullate spidroin 1 | | Authors: | Askarieh, G, Hedhammar, H, Nordling, K, Johansson, J, Knight, S.D, Rising, A, Casals, C, Saenz, A. | | Deposit date: | 2010-02-10 | | Release date: | 2010-05-12 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay.
Nature, 465, 2010
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3LR6
 | | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay | | Descriptor: | Major ampullate spidroin 1, TRIETHYLENE GLYCOL | | Authors: | Askarieh, G, Hedhammar, H, Nordling, K, Saenz, A, Casals, C, Rising, A, Johansson, J, Knight, S.D. | | Deposit date: | 2010-02-10 | | Release date: | 2010-05-12 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay.
Nature, 465, 2010
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3LR8
 | | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Major ampullate spidroin 1, ... | | Authors: | Askarieh, G, Hedhammar, H, Nordling, K, Rising, A, Johansson, J, Knight, S.D. | | Deposit date: | 2010-02-10 | | Release date: | 2010-05-12 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay.
Nature, 465, 2010
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3LRD
 | | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay | | Descriptor: | 1,2-ETHANEDIOL, Major ampullate spidroin 1, TRIETHYLENE GLYCOL | | Authors: | Askarieh, G, Hedhammar, H, Nordling, K, Rising, A, Johansson, J, Knight, S.D, Saenz, A, Casals, C. | | Deposit date: | 2010-02-11 | | Release date: | 2010-05-12 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay.
Nature, 465, 2010
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3NMZ
 | | Crystal structure of APC complexed with Asef | | Descriptor: | APC variant protein, Rho guanine nucleotide exchange factor 4 | | Authors: | Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. | | Deposit date: | 2010-06-23 | | Release date: | 2011-07-06 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
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3NMX
 | | Crystal structure of APC complexed with Asef | | Descriptor: | APC variant protein, Rho guanine nucleotide exchange factor 4 | | Authors: | Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. | | Deposit date: | 2010-06-22 | | Release date: | 2011-07-06 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
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3NMW
 | | Crystal structure of armadillo repeats domain of APC | | Descriptor: | APC variant protein, SULFATE ION | | Authors: | Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. | | Deposit date: | 2010-06-22 | | Release date: | 2011-07-06 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
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3D0T
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1U7V
 | | Crystal Structure of the phosphorylated Smad2/Smad4 heterotrimeric complex | | Descriptor: | Mothers against decapentaplegic homolog 2, Mothers against decapentaplegic homolog 4 | | Authors: | Chacko, B.M, Qin, B.Y, Tiwari, A, Shi, G, Lam, S, Hayward, L.J, de Caestecker, M, Lin, K. | | Deposit date: | 2004-08-04 | | Release date: | 2004-09-28 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis of heteromeric smad protein assembly in tgf-Beta signaling
Mol.Cell, 15, 2004
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