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PDB: 51 results
8FF8
CRYSTAL STRUCTURE OF GLYCOGEN SYNTHASE KINASE 3 BETA COMPLEXED WITH 2-[(4-CYANOPHENYL)AMINO]-N-(4-PHENYLPYRIDIN-3-YL)PYRIMIDINE-4-CARBOXAMIDE
Descriptor:
2-(4-cyanoanilino)-N-(4-phenylpyridin-3-yl)pyrimidine-4-carboxamide, Glycogen synthase kinase-3 beta
Authors:
Muckelbauer, J.K
,
Lewis, H.A.
Deposit date:
2022-12-08
Release date:
2023-06-07
Last modified:
2024-05-22
Method:
X-RAY DIFFRACTION (2.33 Å)
Cite:
Discovery of 2-(Anilino)pyrimidine-4-carboxamides as Highly Potent, Selective, and Orally Active Glycogen Synthase Kinase-3 (GSK-3) Inhibitors.
J.Med.Chem., 66, 2023
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건을2024-10-30부터공개중