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PDB: 18 件
4UUJ
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POTASSIUM CHANNEL KCSA-FAB WITH TETRAHEXYLAMMONIUM
分子名称: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ...
著者Lenaeus, M.J, Burdette, D, Wagner, T, Focia, P.J, Gross, A.
登録日2014-07-29
公開日2014-08-27
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site.
Biochemistry, 53, 2014
8F6P
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Rat Cardiac Sodium Channel with Ranolazine Bound
分子名称: (R)-ranolazine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Lenaeus, M.J, Tonggu, L.
登録日2022-11-16
公開日2023-04-12
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for inhibition of the cardiac sodium channel by the atypical antiarrhythmic drug ranolazine.
Nat Cardiovasc Res, 2, 2023
2W0F
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BU of 2w0f by Molmil
Potassium Channel KcsA-Fab Complex with Tetraoctylammonium
分子名称: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ...
著者Lenaeus, M.J, Focia, P.J, Wagner, T, Gross, A.
登録日2008-08-14
公開日2009-11-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site.
Biochemistry, 53, 2014
2JK5
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BU of 2jk5 by Molmil
Potassium Channel KcsA in complex with Tetrabutylammonium in high K
分子名称: (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, ...
著者Lenaeus, M.J, Focia, P.J, Wagner, T, Gross, A.
登録日2008-08-15
公開日2009-11-17
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site.
Biochemistry, 53, 2014
2BOC
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BU of 2boc by Molmil
Potassium channel KcsA-Fab complex in thallium with tetraethylarsonium (TEAs)
分子名称: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ...
著者Lenaeus, M.J, Vamvouka, M, Focia, P.J, Gross, A.
登録日2005-04-09
公開日2005-04-27
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structural Basis of Tea Blockade in a Model Potassium Channel
Nat.Struct.Mol.Biol., 12, 2005
2BOB
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BU of 2bob by Molmil
Potassium channel KcsA-Fab complex in thallium with tetrabutylammonium (TBA)
分子名称: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ...
著者Lenaeus, M.J, Vamvouka, M, Focia, P.J, Gross, A.
登録日2005-04-09
公開日2005-04-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structural Basis of Tea Blockade in a Model Potassium Channel
Nat.Struct.Mol.Biol., 12, 2005
5VB2
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Crystal structure of the NavAb voltage-gated sodium channel in a closed conformation
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CHLORIDE ION, ...
著者Lenaeus, M.J, Catterall, W.A.
登録日2017-03-28
公開日2017-04-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structures of closed and open states of a voltage-gated sodium channel.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VB8
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Crystal structure of the NavAb voltage-gated sodium channel in an open state
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein, SODIUM ION, ...
著者Lenaeus, M.J, Catterall, W.A.
登録日2017-03-28
公開日2017-04-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structures of closed and open states of a voltage-gated sodium channel.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6MVW
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NavAb voltage-gated sodium channel, I217C/F203W
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein, PHOSPHATE ION
著者Lenaeus, M.J, Catterall, W.A.
登録日2018-10-28
公開日2018-12-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.198 Å)
主引用文献Fenestrations control resting-state block of a voltage-gated sodium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6MWB
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NavAb Voltage-gated Sodium Channel, residues 1-239 with mutation T206A
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein, ...
著者Lenaeus, M.J, Catterall, W.A.
登録日2018-10-29
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb.
J. Gen. Physiol., 151, 2019
6MWD
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NavAb Voltage-gated Sodium Channel, residues 1-239 with mutation T206S
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ACETATE ION, ...
著者Lenaeus, M.J, Catterall, W.A.
登録日2018-10-29
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.327 Å)
主引用文献Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb.
J. Gen. Physiol., 151, 2019
6MVY
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NavAb voltage-gated sodium channel, residues 1-226, crystallized in the presence of Class 1B Anti-arrhythmic drug Lidocaine
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein, SULFATE ION
著者Lenaeus, M.J, Catterall, W.A.
登録日2018-10-28
公開日2018-12-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.002 Å)
主引用文献Fenestrations control resting-state block of a voltage-gated sodium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6MWA
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BU of 6mwa by Molmil
NavAb Voltage-gated Sodium Channel, residues 1-239
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein, ...
著者Lenaeus, M.J, Catterall, W.A.
登録日2018-10-29
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb.
J. Gen. Physiol., 151, 2019
6MVX
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BU of 6mvx by Molmil
NavAb Voltage-gated Sodium Channel, I217C, in Complex with Class 1C Anti-arrhythmic Flecainide
分子名称: Flecainide, Ion transport protein, PHOSPHATE ION
著者Lenaeus, M.J, Catterall, W.A.
登録日2018-10-28
公開日2018-12-05
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.455 Å)
主引用文献Fenestrations control resting-state block of a voltage-gated sodium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6MWG
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BU of 6mwg by Molmil
NavAb Voltage-gated Sodium Channel, residues 1-239, with mutation T206V
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ACETATE ION, ...
著者Lenaeus, M.J, Catterall, W.A.
登録日2018-10-29
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb.
J. Gen. Physiol., 151, 2019
6MVV
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BU of 6mvv by Molmil
NavAb voltage-gated sodium channel, I217C/F203A
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein, PHOSPHATE ION
著者Lenaeus, M.J, Catterall, W.A.
登録日2018-10-28
公開日2018-12-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Fenestrations control resting-state block of a voltage-gated sodium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6UZ3
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BU of 6uz3 by Molmil
Cardiac sodium channel
分子名称: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jiang, D, Shi, H, Tonggu, L, Lenaeus, M.J, Zheng, N, Catterall, W.A.
登録日2019-11-14
公開日2020-01-01
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of the Cardiac Sodium Channel.
Cell, 180, 2020
6UZ0
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BU of 6uz0 by Molmil
Cardiac sodium channel with flecainide
分子名称: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jiang, D, Shi, H, Tonggu, L, Lenaeus, M.J, Zheng, N, Catterall, W.A.
登録日2019-11-14
公開日2020-01-01
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Structure of the Cardiac Sodium Channel.
Cell, 180, 2020

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件を2024-10-30に公開中

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