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PDB: 2 results
4YTC
Discovery of VX-509 (Decernotinib): A Potent and Selective Janus kinase (JAK) 3 Inhibitor for the Treatment of Autoimmune Disease
Descriptor:
N~3~-phenyl-1-[6-(phenylamino)pyrimidin-4-yl]-1H-1,2,4-triazole-3,5-diamine, Tyrosine-protein kinase JAK2
Authors:
Zuccola, H.J
,
Ledeboer, M.
Deposit date:
2015-03-17
Release date:
2015-08-12
Last modified:
2015-10-07
Method:
X-RAY DIFFRACTION (2.16 Å)
Cite:
Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases.
J.Med.Chem., 58, 2015
4YTI
Discovery of VX-509 (Decernotinib): A Potent and Selective Janus kinase (JAK) 3 Inhibitor for the Treatment of Autoimmune Disease
Descriptor:
(2R)-2-methyl-2-[[2-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]-N-[2,2,2-tris(fluoranyl)ethyl]butanamide, Tyrosine-protein kinase JAK2
Authors:
Zuccola, H.J
,
Ledeboer, M.
Deposit date:
2015-03-17
Release date:
2015-08-12
Last modified:
2015-10-07
Method:
X-RAY DIFFRACTION (2.52 Å)
Cite:
Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases.
J.Med.Chem., 58, 2015
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數據於2024-08-28公開中