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PDB: 5 件

4IA9
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BU of 4ia9 by Molmil
Crystal structure of human WD REPEAT DOMAIN 5 in complex with 2-chloro-4-fluoro-3-methyl-N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]benzamide
分子名称: 1,2-ETHANEDIOL, 2-chloro-4-fluoro-3-methyl-N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]benzamide, UNKNOWN ATOM OR ION, ...
著者Dong, A, Dombrovski, L, Bolshan, Y, Getlik, M, Tempel, W, Kuznetsova, E, Wasney, G.A, Hajian, T, Poda, G, Nguyen, K.T, Schapira, M, Brown, P.J, Al-awar, R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Smil, D, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC)
登録日2012-12-06
公開日2012-12-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Synthesis, Optimization, and Evaluation of Novel Small Molecules as Antagonists of WDR5-MLL Interaction.
ACS Med Chem Lett, 4, 2013
4QL1
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BU of 4ql1 by Molmil
Crystal structure of human WDR5 in complex with compound OICR-9429
分子名称: 1,2-ETHANEDIOL, GLYCEROL, N-(4-(4-methylpiperazin-1-yl)-3'-(morpholinomethyl)-[1,1'-biphenyl]-3-yl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide, ...
著者Dong, A, Dombrovski, L, Walker, J.R, Getlik, M, Kuznetsova, E, Smil, D, Barsyte, D, Li, F, Poda, G, Senisterra, G, Marcellus, R, Al-Awar, R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Schapira, M, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC)
登録日2014-06-10
公開日2014-12-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Pharmacological targeting of the Wdr5-MLL interaction in C/EBP alpha N-terminal leukemia.
Nat.Chem.Biol., 11, 2015
1S3N
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BU of 1s3n by Molmil
Structural and Functional Characterization of a Novel Archaeal Phosphodiesterase
分子名称: Hypothetical protein MJ0936, MANGANESE (II) ION
著者Chen, S, Busso, D, Yakunin, A.F, Kuznetsova, E, Proudfoot, M, Jancrick, J, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC)
登録日2004-01-13
公開日2004-08-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and functional characterization of a novel phosphodiesterase from Methanococcus jannaschii
J.Biol.Chem., 279, 2004
1S3M
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BU of 1s3m by Molmil
Structural and Functional Characterization of a Novel Archaeal Phosphodiesterase
分子名称: Hypothetical protein MJ0936, NICKEL (II) ION
著者Chen, S, Busso, D, Yakunin, A.F, Kuznetsova, E, Proudfoot, M, Jancrick, J, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC)
登録日2004-01-13
公開日2004-08-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and functional characterization of a novel phosphodiesterase from Methanococcus jannaschii
J.Biol.Chem., 279, 2004
1S3L
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BU of 1s3l by Molmil
Structural and Functional Characterization of a Novel Archaeal Phosphodiesterase
分子名称: Hypothetical protein MJ0936, PHOSPHATE ION, UNKNOWN ATOM OR ION
著者Chen, S, Busso, D, Yakunin, A.F, Kuznetsova, E, Proudfoot, M, Jancrick, J, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC)
登録日2004-01-13
公開日2004-08-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and functional characterization of a novel phosphodiesterase from Methanococcus jannaschii
J.Biol.Chem., 279, 2004

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件を2024-05-08に公開中

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