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PDB: 2 results

3WJL
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BU of 3wjl by Molmil
Crystal structure of IIb selective Fc variant, Fc(V12), in complex with FcgRIIb
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor II-c, ...
Authors:Kadono, S, Mimoto, F, Katada, H, Igawa, T, Kuramochi, T, Muraoka, M, Wada, Y, Haraya, K, Miyazaki, T, Hattori, K.
Deposit date:2013-10-11
Release date:2013-11-13
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Engineered antibody Fc variant with selectively enhanced Fc gamma RIIb binding over both Fc gamma RIIaR131 and Fc gamma RIIaH131.
Protein Eng.Des.Sel., 26, 2013
3WJJ
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BU of 3wjj by Molmil
Crystal structure of IIb selective Fc variant, Fc(P238D), in complex with FcgRIIb
Descriptor: Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor II-b, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Kadono, S, Mimoto, F, Katada, H, Igawa, T, Kuramochi, T, Muraoka, M, Wada, Y, Haraya, K, Miyazaki, T, Hattori, K.
Deposit date:2013-10-10
Release date:2013-11-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Engineered antibody Fc variant with selectively enhanced Fc gamma RIIb binding over both Fc gamma RIIaR131 and Fc gamma RIIaH131.
Protein Eng.Des.Sel., 26, 2013

226707

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