2W0N
| Plasticity of PAS domain and potential role for signal transduction in the histidine-kinase DcuS | 分子名称: | SENSOR PROTEIN DCUS | 著者 | Etzkorn, M, Kneuper, H, Duennwald, P, Vijayan, V, Kraemer, J, Griesinger, C, Becker, S, Unden, G, Baldus, M. | 登録日 | 2008-08-19 | 公開日 | 2008-09-30 | 最終更新日 | 2024-05-15 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Plasticity of the Pas Domain and a Potential Role for Signal Transduction in the Histidine Kinase Dcus. Nat.Struct.Mol.Biol., 15, 2008
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3MSK
| Fragment Based Discovery and Optimisation of BACE-1 Inhibitors | 分子名称: | 4-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-cyclohexyl-N-methylbutanamide, Beta-secretase 1, GLYCEROL, ... | 著者 | Smith, M.A, Madden, J.M, Barker, J, Godemann, R, Kraemer, J, Hallett, D. | 登録日 | 2010-04-29 | 公開日 | 2010-07-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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3S2O
| Fragment based discovery and optimisation of bace-1 inhibitors | 分子名称: | (3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-[(1R,3S,5R,7R)-tricyclo[3.3.1.1~3,7~]dec-2-yl]pentanamide, Beta-secretase 1, IODIDE ION | 著者 | Madden, J, Godemann, R, Smith, M.A, Hallett, D, Barker, J, Kraemer, J. | 登録日 | 2011-05-17 | 公開日 | 2011-06-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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