8OFB
 
 | | Crystal Structure of T. maritima reverse gyrase with a minimal latch, hexagonal form | | Descriptor: | CHLORIDE ION, HEXAETHYLENE GLYCOL, Reverse gyrase, ... | | Authors: | Klostermeier, D, Rasche, R, Mhaindarkar, V, Kummel, D, Rudolph, M.G. | | Deposit date: | 2023-03-15 | | Release date: | 2023-04-26 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Structure of reverse gyrase with a minimal latch that supports ATP-dependent positive supercoiling without specific interactions with the topoisomerase domain.
Acta Crystallogr D Struct Biol, 79, 2023
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3EAQ
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3EAR
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3EAS
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5MAO
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7FSE
 | | Crystal Structure of T. maritima reverse gyrase with a minimal latch | | Descriptor: | CHLORIDE ION, DODECAETHYLENE GLYCOL, Reverse gyrase, ... | | Authors: | Rasche, R, Kummel, D, Rudolph, M.G, Klostermeier, D. | | Deposit date: | 2023-01-04 | | Release date: | 2023-05-10 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | Structure of reverse gyrase with a minimal latch that supports ATP-dependent positive supercoiling without specific interactions with the topoisomerase domain.
Acta Crystallogr D Struct Biol, 79, 2023
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7FSF
 | | CRYSTAL STRUCTURE OF T. MARITIMA REVERSE GYRASE ACTIVE SITE VARIANT Y851F | | Descriptor: | Reverse gyrase, ZINC ION | | Authors: | Rasche, R, Kummel, D, Rudolph, M.G, Klostermeier, D. | | Deposit date: | 2023-01-04 | | Release date: | 2023-05-10 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Structure of reverse gyrase with a minimal latch that supports ATP-dependent positive supercoiling without specific interactions with the topoisomerase domain.
Acta Crystallogr D Struct Biol, 79, 2023
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3I32
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3I31
 | | Hera helicase RNA binding domain is an RRM fold | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Heat resistant RNA dependent ATPase, SODIUM ION, ... | | Authors: | Rudolph, M.G, Klostermeier, D. | | Deposit date: | 2009-06-30 | | Release date: | 2009-09-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The Thermus thermophilus DEAD box helicase Hera contains a modified RNA recognition motif domain loosely connected to the helicase core.
Rna, 15, 2009
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4KBG
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4KBF
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2GXQ
 | | HERA N-terminal domain in complex with AMP, crystal form 1 | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE MONOPHOSPHATE, heat resistant RNA dependent ATPase | | Authors: | Rudolph, M.G, Klostermeier, D. | | Deposit date: | 2006-05-09 | | Release date: | 2006-08-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Crystal Structure and Nucleotide Binding of the Thermus thermophilus RNA Helicase Hera N-terminal Domain.
J.Mol.Biol., 351, 2006
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2GXS
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2GXU
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3P4X
 | | Helicase domain of reverse gyrase from Thermotoga maritima | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Rudolph, M.G, Klostermeier, D. | | Deposit date: | 2010-10-07 | | Release date: | 2011-06-15 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | The Conformational Flexibility of the Helicase-like Domain from Thermotoga maritima Reverse Gyrase Is Restricted by the Topoisomerase Domain.
Biochemistry, 50, 2011
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3OIY
 | | Helicase domain of reverse gyrase from Thermotoga maritima | | Descriptor: | CHLORIDE ION, PYROPHOSPHATE 2-, reverse gyrase helicase domain | | Authors: | Rudolph, M.G, Klostermeier, D. | | Deposit date: | 2010-08-20 | | Release date: | 2010-12-01 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The latch modulates nucleotide and DNA binding to the helicase-like domain of Thermotoga maritima reverse gyrase and is required for positive DNA supercoiling.
Nucleic Acids Res., 39, 2011
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3P4Y
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4DDV
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3MWL
 | | Q28E mutant of HERA N-terminal RecA-like domain in complex with 8-OXOADENOSINE | | Descriptor: | 6-azanyl-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7H-purin-8-one, Heat resistant RNA dependent ATPase, SULFATE ION | | Authors: | Rudolph, M.G, Klostermeier, D. | | Deposit date: | 2010-05-06 | | Release date: | 2011-03-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop.
Biol.Chem., 392, 2011
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3MWJ
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3MWK
 | | Q28E mutant of HERA N-terminal RecA-like domain, complex with 8-oxo-AMP | | Descriptor: | Heat resistant RNA dependent ATPase, SULFATE ION, [(2R,3S,4R,5R)-5-(6-azanyl-8-oxo-7H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate | | Authors: | Rudolph, M.G, Klostermeier, D. | | Deposit date: | 2010-05-06 | | Release date: | 2011-03-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop.
Biol.Chem., 392, 2011
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3NBF
 | | Q28E mutant of hera helicase N-terminal domain bound to 8-oxo-ADP | | Descriptor: | Heat resistant RNA dependent ATPase, [(2R,3S,4R,5R)-5-(6-azanyl-8-oxo-7H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate, [(2R,3S,4R,5R)-5-(6-azanyl-8-oxo-7H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl phosphono hydrogen phosphate | | Authors: | Rudolph, M.G, Klostermeier, D. | | Deposit date: | 2010-06-03 | | Release date: | 2011-03-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop.
Biol.Chem., 392, 2011
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4I68
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4I67
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4I69
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