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PDB: 30 件

4PFJ
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The structure of bi-acetylated SAHH
分子名称: ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Kavran, J.M, Wang, Y, Cole, P.A, Leahy, D.J.
登録日2014-04-29
公開日2014-10-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Regulation of s-adenosylhomocysteine hydrolase by lysine acetylation.
J.Biol.Chem., 289, 2014
4PGF
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BU of 4pgf by Molmil
The structure of mono-acetylated SAHH
分子名称: ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Kavran, J.M, Wang, Y, Cole, P.A, Leahy, D.J.
登録日2014-05-01
公開日2014-10-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Regulation of s-adenosylhomocysteine hydrolase by lysine acetylation.
J.Biol.Chem., 289, 2014
2Q7E
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The structure of pyrrolysyl-tRNA synthetase bound to an ATP analogue
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Kavran, J.M, Steitz, T.A.
登録日2007-06-06
公開日2007-07-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q7G
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BU of 2q7g by Molmil
Pyrrolysine tRNA Synthetase bound to a pyrrolysine analogue (cyc) and ATP
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kavran, J.M, Steitz, T.A.
登録日2007-06-06
公開日2007-07-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q7H
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Pyrrolysyl-tRNA synthetase bound to adenylated pyrrolysine and pyrophosphate
分子名称: (2R)-2-AMINO-6-({[(2S,3R)-3-METHYLPYRROLIDIN-2-YL]CARBONYL}AMINO)HEXANOYL [(2S,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL HYDROGEN (R)-PHOSPHATE, 1,2-ETHANEDIOL, PYROPHOSPHATE 2-, ...
著者Kavran, J.M, Steitz, T.A.
登録日2007-06-06
公開日2007-07-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3N1Q
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BU of 3n1q by Molmil
Crystal Structure of DhhN bound to CDOFn3
分子名称: CALCIUM ION, Cell adhesion molecule-related/down-regulated by oncogenes, Desert hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-16
公開日2010-06-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1F
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Crystal Structure of IhhN bound to CDOFn3
分子名称: CALCIUM ION, Cell adhesion molecule-related/down-regulated by oncogenes, Indian hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-15
公開日2010-06-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1O
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Crystal structure of IhhN
分子名称: CALCIUM ION, Indian hedgehog protein, ZINC ION
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-16
公開日2010-06-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1G
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Crystal structure of DhhN bound to BOCFn3
分子名称: Brother of CDO, CALCIUM ION, Desert hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-15
公開日2010-06-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1M
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Crystal Structure of IhhN bound to BOCFn3
分子名称: Brother of CDO, CALCIUM ION, Indian hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-15
公開日2010-06-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1P
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Crystal Structure of IhhN bound to BOCFn3
分子名称: Brother of CDO, CALCIUM ION, Indian hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-16
公開日2010-06-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1R
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BU of 3n1r by Molmil
Crystal Structure of ShhN
分子名称: CALCIUM ION, Sonic hedgehog protein, ZINC ION
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-16
公開日2010-06-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Crystal Structure of ShhN
TO BE PUBLISHED
5KRD
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BU of 5krd by Molmil
Crystal structure of haliscomenobacter hydrossis iodotyrosine deiodinase (IYD) bound to FMN and 2-iodophenol (2IP)
分子名称: 2-iodanylphenol, FLAVIN MONONUCLEOTIDE, Nitroreductase
著者Ingavat, N, Kavran, J.M, Sun, Z, Rokita, S.
登録日2016-07-07
公開日2017-02-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase.
Biochemistry, 56, 2017
8FCF
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BU of 8fcf by Molmil
Crystal structure of PLVAP CC1 in I212121 space group
分子名称: Plasmalemma vesicle-associated protein
著者Chang, T.H, Hsieh, F.L, Gu, X, Kavran, J, Gabelli, S.B, Nathans, J.
登録日2022-12-01
公開日2023-03-22
最終更新日2023-04-12
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural insights into plasmalemma vesicle-associated protein (PLVAP): Implications for vascular endothelial diaphragms and fenestrae.
Proc.Natl.Acad.Sci.USA, 120, 2023
6BN1
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BU of 6bn1 by Molmil
Salvador Hippo SARAH domain complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, NICKEL (II) ION, Scaffold protein salvador, ...
著者Cairns, L, Kavran, J.M.
登録日2017-11-15
公開日2018-03-14
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Salvador has an extended SARAH domain that mediates binding to Hippo kinase.
J. Biol. Chem., 293, 2018
6TYK
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BU of 6tyk by Molmil
Crystal structure of iodotyrosine deiodinase (IYD) in the semiquinone form bound to FMN and 3-iodo-L-tyrosine
分子名称: 3-IODO-TYROSINE, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
著者Sun, Z, Kavran, J.M, Rokita, S.E.
登録日2019-08-09
公開日2021-04-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structure of Tn IYD bound in the semiquinone form bound to FMN and 3-iodo-L-tyrosine
To Be Published
2ZIM
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BU of 2zim by Molmil
Pyrrolysyl-tRNA synthetase bound to adenylated pyrrolysine and pyrophosphate
分子名称: (2R)-2-AMINO-6-({[(2S,3R)-3-METHYLPYRROLIDIN-2-YL]CARBONYL}AMINO)HEXANOYL [(2S,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL HYDROGEN (R)-PHOSPHATE, 1,2-ETHANEDIOL, PYROPHOSPHATE 2-, ...
著者Steitz, T.A, Kavran, J.M.
登録日2008-02-19
公開日2008-03-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4Y6C
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BU of 4y6c by Molmil
Q17M crystal structure of Podosopora anserina putative kinesin light chain nearly identical TPR-like repeats
分子名称: ANSERINA PUTATIVE KINESIN LIGHT chain, SULFATE ION
著者Marold, J.D, Kavran, J.M, Bowman, G.D, Barrick, D.
登録日2015-02-12
公開日2015-10-07
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.772 Å)
主引用文献A Naturally Occurring Repeat Protein with High Internal Sequence Identity Defines a New Class of TPR-like Proteins.
Structure, 23, 2015
4Y6W
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Crystal structure of Podosopora anserina putative kinesin light chain nearly identical TPR-like repeats
分子名称: NaB(AB)3ACb - light chain TPR-like repeats
著者Marold, J.D, Kavran, J.M, Bowman, G.D, Barrick, D.
登録日2015-02-13
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.587 Å)
主引用文献A Naturally Occurring Repeat Protein with High Internal Sequence Identity Defines a New Class of TPR-like Proteins.
Structure, 23, 2015
5KO8
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Crystal structure of haliscomenobacter hydrossis iodotyrosine deiodinase (IYD) bound to FMN and mono-iodotyrosine (I-Tyr)
分子名称: 3-IODO-TYROSINE, FLAVIN MONONUCLEOTIDE, Nitroreductase
著者Ingavat, N, Kavran, J.M, Sun, Z, Rokita, S.E.
登録日2016-06-29
公開日2017-02-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase.
Biochemistry, 56, 2017
5KO7
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BU of 5ko7 by Molmil
Crystal structure of haliscomenobacter hydrossis iodotyrosine deiodinase (IYD) bound to FMN
分子名称: FLAVIN MONONUCLEOTIDE, Nitroreductase
著者Ingavat, N, Kavran, J.M, Sun, Z, Rokita, S.
登録日2016-06-29
公開日2017-02-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.248 Å)
主引用文献Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase.
Biochemistry, 56, 2017
6PZ0
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BU of 6pz0 by Molmil
Crystal structure of oxidized iodotyrosine deiodinase (IYD) bound to FMN and L-Tyrosine
分子名称: CHLORIDE ION, FLAVIN MONONUCLEOTIDE, TYROSINE, ...
著者Sun, Z, Kavran, J.M, Rokita, S.E.
登録日2019-07-31
公開日2021-02-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The minimal structure for iodotyrosine deiodinase function is defined by an outlier protein from the thermophilic bacterium Thermotoga neapolitana.
J.Biol.Chem., 297, 2021
6Q1L
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BU of 6q1l by Molmil
Crystal structure of oxidized iodotyrosine deiodinase (IYD) bound to FMN and 3-iodo-L-tyrosine
分子名称: 3-IODO-TYROSINE, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
著者Sun, Z, Kavran, J.M, Rokita, S.E.
登録日2019-08-05
公開日2021-04-07
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The minimal structure for iodotyrosine deiodinase function is defined by an outlier protein from the thermophilic bacterium Thermotoga neapolitana.
J.Biol.Chem., 297, 2021
4Q6G
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BU of 4q6g by Molmil
Crystal Structure of the C-terminal domain of AcKRS-1 bound with N-acetyl-lysine and ADPNP
分子名称: 1,2-ETHANEDIOL, N(6)-ACETYLLYSINE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Eiler, D.R, Kavran, J, Steitz, T.A.
登録日2014-04-22
公開日2014-11-12
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Polyspecific pyrrolysyl-tRNA synthetases from directed evolution.
Proc.Natl.Acad.Sci.USA, 111, 2014
6Q1B
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BU of 6q1b by Molmil
Crystal structure of oxidized iodotyrosine deiodinase (IYD) bound to FMN and 3-fluoro-L-tyrosine
分子名称: 3-FLUOROTYROSINE, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
著者Sun, Z, Kavran, J.M, Rokita, S.E.
登録日2019-08-03
公開日2021-02-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.596 Å)
主引用文献Crystal structure of oxidized Tn IYD bound to FMN and 3-fluoro-L-tyrosine
To Be Published

 

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