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PDB: 34 件
2AY5
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AROMATIC AMINO ACID AMINOTRANSFERASE WITH 3-INDOLEPROPIONIC ACID
分子名称: AROMATIC AMINO ACID AMINOTRANSFERASE, INDOLYLPROPIONIC ACID, PYRIDOXAL-5'-PHOSPHATE
著者Okamoto, A, Hirotsu, K, Kagamiyama, H.
登録日1998-08-06
公開日1999-02-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The active site of Paracoccus denitrificans aromatic amino acid aminotransferase has contrary properties: flexibility and rigidity.
Biochemistry, 38, 1999
1YOO
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ASPARTATE AMINOTRANSFERASE MUTANT ATB17 WITH ISOVALERIC ACID
分子名称: ASPARTATE AMINOTRANSFERASE, ISOVALERIC ACID, PYRIDOXAL-5'-PHOSPHATE
著者Oue, S, Okamoto, A, Yano, T, Kagamiyama, H.
登録日1998-06-26
公開日1999-02-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Redesigning the substrate specificity of an enzyme by cumulative effects of the mutations of non-active site residues.
J.Biol.Chem., 274, 1999
1SPA
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ROLE OF ASP222 IN THE CATALYTIC MECHANISM OF ESCHERICHIA COLI ASPARTATE AMINOTRANSFERASE: THE AMINO ACID RESIDUE WHICH ENHANCES THE FUNCTION OF THE ENZYME-BOUND COENZYME PYRIDOXAL 5'-PHOSPHATE
分子名称: ASPARTATE AMINOTRANSFERASE, N-METHYL-4-DEOXY-4-AMINO-PYRIDOXAL-5-PHOSPHATE
著者Hinoue, Y, Yano, T, Metzler, D.E, Miyahara, I, Hirotsu, K, Kagamiyama, H.
登録日1993-01-26
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Role of Asp222 in the catalytic mechanism of Escherichia coli aspartate aminotransferase: the amino acid residue which enhances the function of the enzyme-bound coenzyme pyridoxal 5'-phosphate.
Biochemistry, 31, 1992
1G7X
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ASPARTATE AMINOTRANSFERASE ACTIVE SITE MUTANT N194A/R292L/R386L
分子名称: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
著者Mizuguchi, H, Hayashi, H, Okada, K, Miyahara, I, Hirotsu, K, Kagamiyama, H.
登録日2000-11-15
公開日2000-11-29
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Strain is more important than electrostatic interaction in controlling the pKa of the catalytic group in aspartate aminotransferase.
Biochemistry, 40, 2001
1G4V
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ASPARTATE AMINOTRANSFERASE ACTIVE SITE MUTANT N194A/Y225F
分子名称: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
著者Mizuguchi, H, Hayashi, H, Okada, K, Miyahara, I, Hirotsu, K, Kagamiyama, H.
登録日2000-10-28
公開日2000-11-22
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Strain is more important than electrostatic interaction in controlling the pKa of the catalytic group in aspartate aminotransferase.
Biochemistry, 40, 2001
1G7W
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ASPARTATE AMINOTRANSFERASE ACTIVE SITE MUTANT N194A/R386L
分子名称: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
著者Mizuguchi, H, Hayashi, H, Okada, K, Miyahara, I, Hirotsu, K, Kagamiyama, H.
登録日2000-11-15
公開日2000-11-29
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Strain is more important than electrostatic interaction in controlling the pKa of the catalytic group in aspartate aminotransferase.
Biochemistry, 40, 2001
2AY8
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AROMATIC AMINO ACID AMINOTRANSFERASE WITH 4-(2-THIENYL)BUTYRIC ACID
分子名称: 4-(2-THIENYL)BUTYRIC ACID, AROMATIC AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
著者Okamoto, A, Hirotsu, K, Kagamiyama, H.
登録日1998-08-06
公開日1999-02-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The active site of Paracoccus denitrificans aromatic amino acid aminotransferase has contrary properties: flexibility and rigidity.
Biochemistry, 38, 1999
2AY9
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AROMATIC AMINO ACID AMINOTRANSFERASE WITH 5-PHENYLVALERIC ACID
分子名称: 5-PHENYLVALERIC ACID, AROMATIC AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
著者Okamoto, A, Hirotsu, K, Kagamiyama, H.
登録日1998-08-06
公開日1999-02-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The active site of Paracoccus denitrificans aromatic amino acid aminotransferase has contrary properties: flexibility and rigidity.
Biochemistry, 38, 1999
2AY6
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AROMATIC AMINO ACID AMINOTRANSFERASE WITH 3-INDOLEBUTYRIC ACID
分子名称: 3-INDOLEBUTYRIC ACID, AROMATIC AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
著者Okamoto, A, Hirotsu, K, Kagamiyama, H.
登録日1998-08-06
公開日1999-02-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The active site of Paracoccus denitrificans aromatic amino acid aminotransferase has contrary properties: flexibility and rigidity.
Biochemistry, 38, 1999
2AY4
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AROMATIC AMINO ACID AMINOTRANSFERASE WITH 3-(P-TOLYL)PROPIONIC ACID
分子名称: 3-(P-TOLYL)PROPIONIC ACID, AROMATIC AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
著者Okamoto, A, Hirotsu, K, Kagamiyama, H.
登録日1998-08-06
公開日1999-02-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The active site of Paracoccus denitrificans aromatic amino acid aminotransferase has contrary properties: flexibility and rigidity.
Biochemistry, 38, 1999
2AY1
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AROMATIC AMINO ACID AMINOTRANSFERASE WITH 4-AMINOHYDROCINNAMIC ACID
分子名称: 4-AMINOHYDROCINNAMIC ACID, AROMATIC AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
著者Okamoto, A, Hirotsu, K, Kagamiyama, H.
登録日1998-08-06
公開日1999-02-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The active site of Paracoccus denitrificans aromatic amino acid aminotransferase has contrary properties: flexibility and rigidity.
Biochemistry, 38, 1999
2AY2
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AROMATIC AMINO ACID AMINOTRANSFERASE WITH CYCLOHEXANE PROPIONIC ACID
分子名称: AROMATIC AMINO ACID AMINOTRANSFERASE, CYCLOHEXANE PROPIONIC ACID, PYRIDOXAL-5'-PHOSPHATE
著者Okamoto, A, Hirotsu, K, Kagamiyama, H.
登録日1998-08-06
公開日1999-02-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The active site of Paracoccus denitrificans aromatic amino acid aminotransferase has contrary properties: flexibility and rigidity.
Biochemistry, 38, 1999
2AY7
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AROMATIC AMINO ACID AMINOTRANSFERASE WITH 4-PHENYLBUTYRIC ACID
分子名称: 4-PHENYL-BUTANOIC ACID, AROMATIC AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
著者Okamoto, A, Hirotsu, K, Kagamiyama, H.
登録日1998-08-06
公開日1999-02-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The active site of Paracoccus denitrificans aromatic amino acid aminotransferase has contrary properties: flexibility and rigidity.
Biochemistry, 38, 1999
2AY3
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AROMATIC AMINO ACID AMINOTRANSFERASE WITH 3-(3,4-DIMETHOXYPHENYL)PROPIONIC ACID
分子名称: 3-(3,4-DIMETHOXYPHENYL)PROPIONIC ACID, AROMATIC AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
著者Okamoto, A, Hirotsu, K, Kagamiyama, H.
登録日1998-08-06
公開日1999-02-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The active site of Paracoccus denitrificans aromatic amino acid aminotransferase has contrary properties: flexibility and rigidity.
Biochemistry, 38, 1999
1CZE
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ASPARTATE AMINOTRANSFERASE MUTANT ATB17/139S/142N WITH SUCCINIC ACID
分子名称: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, SUCCINIC ACID
著者Okamoto, A, Oue, S, Yano, T, Kagamiyama, H.
登録日1999-09-02
公開日2000-02-28
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Cocrystallization of a mutant aspartate aminotransferase with a C5-dicarboxylic substrate analog: structural comparison with the enzyme-C4-dicarboxylic analog complex.
J.Biochem.(Tokyo), 127, 2000
1CZC
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ASPARTATE AMINOTRANSFERASE MUTANT ATB17/139S/142N WITH GLUTARIC ACID
分子名称: GLUTARIC ACID, PROTEIN (ASPARTATE AMINOTRANSFERASE), PYRIDOXAL-5'-PHOSPHATE
著者Okamoto, A, Oue, S, Yano, T, Kagamiyama, H.
登録日1999-09-02
公開日2000-02-28
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Cocrystallization of a mutant aspartate aminotransferase with a C5-dicarboxylic substrate analog: structural comparison with the enzyme-C4-dicarboxylic analog complex.
J.Biochem.(Tokyo), 127, 2000
1AY4
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AROMATIC AMINO ACID AMINOTRANSFERASE WITHOUT SUBSTRATE
分子名称: AROMATIC AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
著者Okamoto, A, Hirotsu, K, Kagamiyama, H.
登録日1997-11-14
公開日1998-10-14
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystal structures of Paracoccus denitrificans aromatic amino acid aminotransferase: a substrate recognition site constructed by rearrangement of hydrogen bond network.
J.Mol.Biol., 280, 1998
1AY5
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AROMATIC AMINO ACID AMINOTRANSFERASE COMPLEX WITH MALEATE
分子名称: AROMATIC AMINO ACID AMINOTRANSFERASE, MALEIC ACID, PYRIDOXAL-5'-PHOSPHATE
著者Okamoto, A, Hirotsu, K, Kagamiyama, H.
登録日1997-11-14
公開日1998-10-14
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of Paracoccus denitrificans aromatic amino acid aminotransferase: a substrate recognition site constructed by rearrangement of hydrogen bond network.
J.Mol.Biol., 280, 1998
1AY8
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AROMATIC AMINO ACID AMINOTRANSFERASE COMPLEX WITH 3-PHENYLPROPIONATE
分子名称: AROMATIC AMINO ACID AMINOTRANSFERASE, HYDROCINNAMIC ACID, PYRIDOXAL-5'-PHOSPHATE
著者Okamoto, A, Hirotsu, K, Kagamiyama, H.
登録日1997-11-14
公開日1998-10-14
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of Paracoccus denitrificans aromatic amino acid aminotransferase: a substrate recognition site constructed by rearrangement of hydrogen bond network.
J.Mol.Biol., 280, 1998
1GEX
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CRYSTAL STRUCTURE OF HISTIDINOL-PHOSPHATE AMINOTRANSFERASE COMPLEXED WITH HISTIDINOL-PHOSPHATE
分子名称: HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, PHOSPHORIC ACID MONO-[2-AMINO-3-(3H-IMIDAZOL-4-YL)-PROPYL]ESTER, PYRIDOXAL-5'-PHOSPHATE
著者Haruyama, K, Nakai, T, Miyahara, I, Hirotsu, K, Mizuguchi, H, Hayashi, H, Kagamiyama, H.
登録日2000-11-30
公開日2001-04-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of Escherichia coli histidinol-phosphate aminotransferase and its complexes with histidinol-phosphate and N-(5'-phosphopyridoxyl)-L-glutamate: double substrate recognition of the enzyme.
Biochemistry, 40, 2001
1GEY
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CRYSTAL STRUCTURE OF HISTIDINOL-PHOSPHATE AMINOTRANSFERASE COMPLEXED WITH N-(5'-PHOSPHOPYRIDOXYL)-L-GLUTAMATE
分子名称: 4-[(1,3-DICARBOXY-PROPYLAMINO)-METHYL]-3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDINIUM, HISTIDINOL-PHOSPHATE AMINOTRANSFERASE
著者Haruyama, K, Nakai, T, Miyahara, I, Hirotsu, K, Mizuguchi, H, Hayashi, H, Kagamiyama, H.
登録日2000-11-30
公開日2001-04-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of Escherichia coli histidinol-phosphate aminotransferase and its complexes with histidinol-phosphate and N-(5'-phosphopyridoxyl)-L-glutamate: double substrate recognition of the enzyme.
Biochemistry, 40, 2001
1GEW
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CRYSTAL STRUCTURE OF HISTIDINOL-PHOSPHATE AMINOTRANSFERASE COMPLEXED WITH PYRIDOXAL 5'-PHOSPHATE
分子名称: HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
著者Haruyama, K, Nakai, T, Miyahara, I, Hirotsu, K, Mizuguchi, H, Hayashi, H, Kagamiyama, H.
登録日2000-11-30
公開日2001-04-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of Escherichia coli histidinol-phosphate aminotransferase and its complexes with histidinol-phosphate and N-(5'-phosphopyridoxyl)-L-glutamate: double substrate recognition of the enzyme.
Biochemistry, 40, 2001
1IX8
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Aspartate Aminotransferase Active Site Mutant V39F/N194A
分子名称: Aspartate Aminotransferase, PYRIDOXAL-5'-PHOSPHATE
著者Hayashi, H, Mizuguchi, H, Miyahara, I, Nakajima, Y, Hirotsu, K, Kagamiyama, H.
登録日2002-06-14
公開日2002-07-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conformational change in aspartate aminotransferase on substrate binding induces strain in the catalytic group and enhances catalysis
J.BIOL.CHEM., 278, 2003
1IX7
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Aspartate Aminotransferase Active Site Mutant V39F maleate complex
分子名称: Aspartate Aminotransferase, MALEIC ACID, PYRIDOXAL-5'-PHOSPHATE
著者Hayashi, H, Mizuguchi, H, Miyahara, I, Nakajima, Y, Hirotsu, K, Kagamiyama, H.
登録日2002-06-14
公開日2002-07-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conformational change in aspartate aminotransferase on substrate binding induces strain in the catalytic group and enhances catalysis
J.BIOL.CHEM., 278, 2003
1IX6
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Aspartate Aminotransferase Active Site Mutant V39F
分子名称: Aspartate Aminotransferase, PYRIDOXAL-5'-PHOSPHATE
著者Hayashi, H, Mizuguchi, H, Miyahara, I, Nakajima, Y, Hirotsu, K, Kagamiyama, H.
登録日2002-06-14
公開日2002-07-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conformational change in aspartate aminotransferase on substrate binding induces strain in the catalytic group and enhances catalysis
J.BIOL.CHEM., 278, 2003

 

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