2MBV
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![BU of 2mbv by Molmil](/molmil-images/mine/2mbv) | LMO4-LIM2 in complex with DEAF1 (404-418) | 分子名称: | Fusion protein of LIM domain transcription factor LMO4 (77-147) and DEAF1 (404-418), ZINC ION | 著者 | Joseph, S, Matthews, J.M, Kwan, A.H.-Y, Mackay, J.P, Cubeddu, L, Foo, P. | 登録日 | 2013-08-06 | 公開日 | 2014-08-20 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural characterisation of LIM-only protein 4 (LMO4) in complex with Deformed Epidermal Autoregulatory Factor-1 (DEAF1) To be Published
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7UI6
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![BU of 7ui6 by Molmil](/molmil-images/mine/7ui6) | |
6U0D
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![BU of 6u0d by Molmil](/molmil-images/mine/6u0d) | |
6UWU
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![BU of 6uwu by Molmil](/molmil-images/mine/6uwu) | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor ZL0516 | 分子名称: | 1,2-ETHANEDIOL, 2-{4-[(2R)-2-hydroxy-3-(4-methylpiperazin-1-yl)propoxy]-3,5-dimethylphenyl}-5,7-dimethoxy-4H-1-benzopyran-4-one, Bromodomain-containing protein 4 | 著者 | Leonard, P.G, Joseph, S. | 登録日 | 2019-11-05 | 公開日 | 2020-04-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of Orally Bioavailable Chromone Derivatives as Potent and Selective BRD4 Inhibitors: Scaffold Hopping, Optimization, and Pharmacological Evaluation. J.Med.Chem., 63, 2020
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2GV3
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![BU of 2gv3 by Molmil](/molmil-images/mine/2gv3) | Translocation of a tRNA with an extended anticodon through the ribosome | 分子名称: | 5'-R(*GP*GP*CP*CP*AP*GP*AP*CP*UP*CP*CP*CP*GP*AP*AP*UP*CP*UP*GP*GP*CP*C)-3' | 著者 | Phelps, S.S, Gaudin, C, Yoshizawa, S, Benitez, C, Fourmy, D, Joseph, S. | 登録日 | 2006-05-02 | 公開日 | 2006-08-08 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Translocation of a tRNA with an Extended Anticodon Through the Ribosome. J.Mol.Biol., 360, 2006
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2UXD
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![BU of 2uxd by Molmil](/molmil-images/mine/2uxd) | Crystal structure of an extended tRNA anticodon stem loop in complex with its cognate mRNA CGGG in the context of the Thermus thermophilus 30S subunit. | 分子名称: | 16S RIBOSOMAL RNA, A-SITE MESSENGER RNA FRAGMENT CGGG, ANTICODON STEM-LOOP OF TRANSFER RNA WITH ANTICODON CCCG, ... | 著者 | Dunham, C.M, Selmer, M, Phelps, S.S, Kelley, A.C, Suzuki, T, Joseph, S, Ramakrishnan, V. | 登録日 | 2007-03-28 | 公開日 | 2007-10-02 | 最終更新日 | 2019-10-30 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structures of Trnas with an Expanded Anticodon Loop in the Decoding Center of the 30S Ribosomal Subunit. RNA, 13, 2007
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2UXB
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![BU of 2uxb by Molmil](/molmil-images/mine/2uxb) | Crystal structure of an extended tRNA anticodon stem loop in complex with its cognate mRNA GGGU in the context of the Thermus thermophilus 30S subunit. | 分子名称: | 16S RIBOSOMAL RNA, A-SITE MESSENGER RNA FRAGMENT GGGU, ANTICODON STEM-LOOP OF TRANSFER RNA WITH ANTICODON ACCC, ... | 著者 | Dunham, C.M, Selmer, M, Phelps, S.S, Kelley, A.C, Suzuki, T, Joseph, S, Ramakrishnan, V. | 登録日 | 2007-03-28 | 公開日 | 2007-07-31 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structures of tRNAs with an expanded anticodon loop in the decoding center of the 30S ribosomal subunit. RNA, 13, 2007
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2UXC
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![BU of 2uxc by Molmil](/molmil-images/mine/2uxc) | Crystal structure of an extended tRNA anticodon stem loop in complex with its cognate mRNA UCGU in the context of the Thermus thermophilus 30S subunit. | 分子名称: | 16S RIBOSOMAL RNA, A-SITE MESSENGER RNA FRAGMENT CGGG, ANTICODON STEM-LOOP OF TRANSFER RNA WITH ANTICODON ACGA, ... | 著者 | Dunham, C.M, Selmer, M, Phelps, S.S, Kelley, A.C, Suzuki, T, Joseph, S, Ramakrishnan, V. | 登録日 | 2007-03-28 | 公開日 | 2007-05-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structures of Trnas with an Expanded Anticodon Loop in the Decoding Center of the 30S Ribosomal Subunit. RNA, 13, 2007
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6WU8
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![BU of 6wu8 by Molmil](/molmil-images/mine/6wu8) | Structure of human SHP2 in complex with inhibitor IACS-13909 | 分子名称: | 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methylpiperidin-4-amine, Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Leonard, P.G, Joseph, S, Rodenberger, A. | 登録日 | 2020-05-04 | 公開日 | 2021-03-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib. Cancer Res., 80, 2020
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7UI7
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![BU of 7ui7 by Molmil](/molmil-images/mine/7ui7) | |