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PDB: 107 件
3P2S
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BU of 3p2s by Molmil
Crystal structure of the fluoroacetyl-CoA-specific thioesterase FlK in an open conformation
分子名称: Fluoroacetyl coenzyme A thioesterase
著者Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y.
登録日2010-10-04
公開日2010-10-20
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
3P2R
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BU of 3p2r by Molmil
Crystal structure of the fluoroacetyl-CoA-specific thioesterase FlK in complex with fluoroacetate
分子名称: Fluoroacetyl coenzyme A thioesterase, fluoroacetic acid
著者Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y.
登録日2010-10-03
公開日2010-10-20
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
7QQR
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BU of 7qqr by Molmil
SpCas9 bound to AAVS1 off-target5 DNA substrate
分子名称: 1,2-ETHANEDIOL, AAVS1 off-target5 non-target strand, AAVS1 off-target5 target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQV
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BU of 7qqv by Molmil
SpCas9 bound to FANCF off-target3 DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target3 non-target strand, FANCF off-target3 target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QR5
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BU of 7qr5 by Molmil
SpCas9 bound to FANCF off-target6 DNA substrate
分子名称: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target6 non-target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-17
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQP
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BU of 7qqp by Molmil
SpCas9 bound to AAVS1 off-target3 DNA substrate
分子名称: 1,2-ETHANEDIOL, AAVS1 off-target3 non-target strand, AAVS1 off-target3 target strand, ...
著者Pacesa, M, JInek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQS
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BU of 7qqs by Molmil
SpCas9 bound to FANCF on-target DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF on-target non-target strand, FANCF on-target target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQO
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BU of 7qqo by Molmil
SpCas9 bound to AAVS1 off-target1 DNA substrate
分子名称: AAVS1 off-target1 non-target strand, AAVS1 off-target1 target strand, AAVS1 sgRNA, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQQ
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BU of 7qqq by Molmil
SpCas9 bound to AAVS1 off-target4 DNA substrate
分子名称: 1,2-ETHANEDIOL, AAVS1 off-target4 non-target strand, AAVS1 off-target4 target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQU
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BU of 7qqu by Molmil
SpCas9 bound to FANCF off-target2 DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target2 non-target strand, FANCF off-target2 target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQX
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BU of 7qqx by Molmil
SpCas9 bound to FANCF off-target5 DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target5 non-target strand, FANCF off-target5 target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQT
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BU of 7qqt by Molmil
SpCas9 bound to FANCF off-target1 DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target1 non-target strand, FANCF off-target1 target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QR0
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BU of 7qr0 by Molmil
SpCas9 bound to TRAC off-target1 DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QR8
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BU of 7qr8 by Molmil
SpCas9 bound to PTPRC off-target1 DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQZ
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BU of 7qqz by Molmil
SpCas9 bound to FANCF off-target7 DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target7 non-target strand, FANCF off-target7 target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQW
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BU of 7qqw by Molmil
SpCas9 bound to FANCF off-target4 DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target4 non-target strand, FANCF off-target4 target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QR1
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BU of 7qr1 by Molmil
SpCas9 bound to TRAC off-target2 DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QR7
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BU of 7qr7 by Molmil
SpCas9 bound to AAVS1 off-target2 DNA substrate
分子名称: AAVS1 off-target2 non-target strand, AAVS1 off-target2 target strand, AAVS1 sgRNA, ...
著者Pacesa, M, JInek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
5FW3
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BU of 5fw3 by Molmil
Crystal structure of SpCas9 variant VRER bound to sgRNA and TGCG PAM target DNA
分子名称: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ...
著者Anders, C, Bargsten, K, Jinek, M.
登録日2016-02-11
公開日2016-06-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.
Mol.Cell, 61, 2016
5FSH
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BU of 5fsh by Molmil
Crystal structure of Thermus thermophilus Csm6
分子名称: CSM6, NICKEL (II) ION
著者Niewoehner, O, Jinek, M.
登録日2016-01-06
公開日2016-01-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Structural Basis for the Endoribonuclease Activity of the Type III-A Crispr-Associated Protein Csm6.
RNA, 22, 2016
5FW2
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BU of 5fw2 by Molmil
Crystal structure of SpCas9 variant EQR bound to sgRNA and TGAG PAM target DNA
分子名称: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ...
著者Anders, C, Bargsten, K, Jinek, M.
登録日2016-02-11
公開日2016-06-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.676 Å)
主引用文献Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.
Mol.Cell, 61, 2016
3P3F
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BU of 3p3f by Molmil
Crystal structure of the F36A mutant of the fluoroacetyl-CoA-specific thioesterase FlK
分子名称: Fluoroacetyl coenzyme A thioesterase
著者Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y.
登録日2010-10-04
公開日2010-10-20
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
3P2Q
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BU of 3p2q by Molmil
Crystal structure of the fluoroacetyl-CoA-specific thioesterase, FlK
分子名称: Fluoroacetyl coenzyme A thioesterase
著者Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y.
登録日2010-10-03
公開日2010-10-20
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
6I0S
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BU of 6i0s by Molmil
Crystal structure of DmTailor in complex with UMPNPP
分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, Terminal uridylyltransferase Tailor
著者Kroupova, A, Ivascu, A, Jinek, M.
登録日2018-10-26
公開日2018-12-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor.
Nucleic Acids Res., 47, 2019
6I0V
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BU of 6i0v by Molmil
Crystal structure of DmTailor in complex with CACAGU RNA
分子名称: MAGNESIUM ION, RNA (5'-R(*CP*AP*CP*AP*GP*U)-3'), Terminal uridylyltransferase Tailor
著者Kroupova, A, Ivascu, A, Jinek, M.
登録日2018-10-26
公開日2018-12-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor.
Nucleic Acids Res., 47, 2019

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