7NYK
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7NYM
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![BU of 7nym by Molmil](/molmil-images/mine/7nym) | Mutant V517A - SH3 domain of JNK-interacting Protein 1 (JIP1) | 分子名称: | HEXAETHYLENE GLYCOL, PHOSPHATE ION, SH3 domain of JNK-interacting Protein 1 (JIP1), ... | 著者 | Perez, L.M, Ielasi, F.S, Palencia, A, Jensen, M.R. | 登録日 | 2021-03-23 | 公開日 | 2021-12-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.614 Å) | 主引用文献 | Visualizing protein breathing motions associated with aromatic ring flipping. Nature, 602, 2022
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7NZB
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![BU of 7nzb by Molmil](/molmil-images/mine/7nzb) | Mutant V517L of the SH3 domain of JNK-interacting protein 1 (JIP1) | 分子名称: | PHOSPHATE ION, SH3 domain of JNK-interacting protein 1 (JIP1), TETRAETHYLENE GLYCOL | 著者 | Perez, L.M, Ielasi, F.S, Jensen, M.R, Palencia, A. | 登録日 | 2021-03-23 | 公開日 | 2021-12-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.959 Å) | 主引用文献 | Visualizing protein breathing motions associated with aromatic ring flipping. Nature, 602, 2022
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7NYN
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![BU of 7nyn by Molmil](/molmil-images/mine/7nyn) | Mutant Y526A of SH3 domain of JNK-interacting Protein 1 (JIP1) | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, ... | 著者 | Perez, L.M, Ielasi, F.S, Palencia, A, Jensen, M.R. | 登録日 | 2021-03-23 | 公開日 | 2021-12-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.537 Å) | 主引用文献 | Visualizing protein breathing motions associated with aromatic ring flipping. Nature, 602, 2022
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7NYL
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![BU of 7nyl by Molmil](/molmil-images/mine/7nyl) | Mutant H493A of SH3 domain of JNK-interacting Protein 1 (JIP1) | 分子名称: | SH3 domain of JNK-interacting Protein 1 (JIP1), TETRAETHYLENE GLYCOL, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | 著者 | Perez, L.M, Ielasi, F.S, Palencia, A, Jensen, M.R. | 登録日 | 2021-03-23 | 公開日 | 2021-12-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Visualizing protein breathing motions associated with aromatic ring flipping. Nature, 602, 2022
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7NZD
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![BU of 7nzd by Molmil](/molmil-images/mine/7nzd) | Fourth SH3 domain of POSH (Plenty of SH3 Domains protein) | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase SH3RF1 | 著者 | Palencia, A, Bessa, L.M, Jensen, M.R. | 登録日 | 2021-03-23 | 公開日 | 2021-12-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Visualizing protein breathing motions associated with aromatic ring flipping. Nature, 602, 2022
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3ZDO
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![BU of 3zdo by Molmil](/molmil-images/mine/3zdo) | Tetramerization domain of Measles virus phosphoprotein | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, PHOSPHOPROTEIN | 著者 | Communie, G, Crepin, T, Jensen, M.R, Blackledge, M, Ruigrok, R.W.H. | 登録日 | 2012-11-29 | 公開日 | 2013-04-24 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Structure of the Tetramerization Domain of Measles Virus Phosphoprotein. J.Virol., 87, 2013
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7LTE
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![BU of 7lte by Molmil](/molmil-images/mine/7lte) | Structure of the alpha-N-methyltransferase (SonM) and RiPP precursor (SonA) heteromeric complex (with SAH) | 分子名称: | LigA domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE, TP-methylase family protein | 著者 | Miller, F.S, Crone, K.K, Jensen, M.R, Shaw, S, Harcombe, W.R, Elias, M, Freeman, M.F. | 登録日 | 2021-02-19 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis. Nat Commun, 12, 2021
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7LTC
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![BU of 7ltc by Molmil](/molmil-images/mine/7ltc) | Structure of the alpha-N-methyltransferase (SonM) and RiPP precursor (SonA) heteromeric complex (no cofactor) | 分子名称: | LigA domain-containing protein, TP-methylase family protein | 著者 | Miller, F.S, Crone, K.K, Jensen, M.R, Shaw, S, Harcombe, W.R, Elias, M, Freeman, M.F. | 登録日 | 2021-02-19 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis. Nat Commun, 12, 2021
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7LTF
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![BU of 7ltf by Molmil](/molmil-images/mine/7ltf) | Structure of the alpha-N-methyltransferase (SonM mutant Y58F) and RiPP precursor (SonA) heteromeric complex (no cofactor) | 分子名称: | LigA domain-containing protein, TP-methylase family protein | 著者 | Miller, F.S, Crone, K.K, Jensen, M.R, Shaw, S, Harcombe, W.R, Elias, M, Freeman, M.F. | 登録日 | 2021-02-19 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis. Nat Commun, 12, 2021
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7LTR
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![BU of 7ltr by Molmil](/molmil-images/mine/7ltr) | Structure of the heteromeric complex between the alpha-N-methyltransferase (SonM) and a truncated construct of the RiPP precursor (SonA) (with SAM) | 分子名称: | GLYCEROL, LigA domain-containing protein, S-ADENOSYLMETHIONINE, ... | 著者 | Miller, F.S, Crone, K.K, Jensen, M.R, Shaw, S, Harcombe, W.R, Elias, M, Freeman, M.F. | 登録日 | 2021-02-19 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis. Nat Commun, 12, 2021
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7LTH
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![BU of 7lth by Molmil](/molmil-images/mine/7lth) | Structure of the alpha-N-methyltransferase (SonM mutant Y93F) and RiPP precursor (SonA) heteromeric complex (no cofactor) | 分子名称: | LigA domain-containing protein, TP-methylase family protein | 著者 | Miller, F.S, Crone, K.K, Jensen, M.R, Shaw, S, Harcombe, W.R, Elias, M, Freeman, M.F. | 登録日 | 2021-02-19 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis. Nat Commun, 12, 2021
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7LTS
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![BU of 7lts by Molmil](/molmil-images/mine/7lts) | Structure of the alpha-N-methyltransferase (SonM mutant R67A) and RiPP precursor (SonA) heteromeric complex (with SAH) | 分子名称: | LigA domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE, TP-methylase family protein | 著者 | Miller, F.S, Crone, K.K, Jensen, M.R, Shaw, S, Harcombe, W.R, Elias, M, Freeman, M.F. | 登録日 | 2021-02-20 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis. Nat Commun, 12, 2021
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4CO6
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![BU of 4co6 by Molmil](/molmil-images/mine/4co6) | Crystal structure of the Nipah virus RNA free nucleoprotein- phosphoprotein complex | 分子名称: | BROMIDE ION, CHLORIDE ION, NUCLEOPROTEIN, ... | 著者 | Yabukarksi, F, Lawrence, P, Tarbouriech, N, Bourhis, J.M, Jensen, M.R, Ruigrok, R.W.H, Blackledge, M, Volchkov, V, Jamin, M. | 登録日 | 2014-01-27 | 公開日 | 2014-08-13 | 最終更新日 | 2014-09-17 | 実験手法 | X-RAY DIFFRACTION (2.498 Å) | 主引用文献 | Structure of Nipah Virus Unassembled Nucleoprotein in Complex with its Viral Chaperone. Nat.Struct.Mol.Biol., 21, 2014
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4FCP
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![BU of 4fcp by Molmil](/molmil-images/mine/4fcp) | Targetting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo [2,3-d] pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization | 分子名称: | Heat shock protein HSP 90-alpha, N,N-dimethyl-7H-purin-6-amine | 著者 | Davies, N.G.M, Browne, H, Davies, B, Foloppe, N, Geoffrey, S, Gibbons, B, Hart, T, Drysdale, M, Mansell, H, Massey, A, Matassova, N, Moore, J.D, Murray, J, Pratt, R, Ray, S, Roughley, S.D, Jensen, M.R, Schoepfer, J, Scriven, K, Simmonite, H, Stokes, S, Surgenor, A, Webb, P, Wright, L, Brough, P. | 登録日 | 2012-05-25 | 公開日 | 2012-10-24 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization. Bioorg.Med.Chem., 20, 2012
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4FCR
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![BU of 4fcr by Molmil](/molmil-images/mine/4fcr) | Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization | 分子名称: | 2-{[4-(2-chloro-4,5-dimethoxyphenyl)-5-cyano-7H-pyrrolo[2,3-d]pyrimidin-2-yl]sulfanyl}-N,N-dimethylacetamide, Heat shock protein HSP 90-alpha | 著者 | Davies, N.G, Browne, H, Davis, B, Foloppe, N, Geoffrey, S, Gibbons, B, Hart, T, Drysdale, M.J, Mansell, H, Massey, A, Matassova, N, Moore, J.D, Murray, J, Pratt, R, Ray, S, Roughley, S.D, Jensen, M.R, Schoepfer, J, Scriven, K, Simmonite, H, Stokes, S, Surgenor, A, Webb, P, Wright, L, Brough, P. | 登録日 | 2012-05-25 | 公開日 | 2012-10-24 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization. Bioorg.Med.Chem., 20, 2012
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4FCQ
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![BU of 4fcq by Molmil](/molmil-images/mine/4fcq) | Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization | 分子名称: | 4-(2,4-dimethylphenyl)-2-(methylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Heat shock protein HSP 90-alpha | 著者 | Davies, N.G, Browne, H, Davis, B, Foloppe, N, Geoffrey, S, Gibbons, B, Hart, T, Drysdale, M.J, Mansell, H, Massey, A, Matassova, N, Moore, J.D, Murray, J, Pratt, R, Ray, S, Roughley, S.D, Jensen, M.R, Schoepfer, J, Scriven, K, Simmonite, H, Stokes, S, Surgenor, A, Webb, P, Wright, L, Brough, P. | 登録日 | 2012-05-25 | 公開日 | 2012-10-24 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.151 Å) | 主引用文献 | Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization. Bioorg.Med.Chem., 20, 2012
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2K6U
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![BU of 2k6u by Molmil](/molmil-images/mine/2k6u) | The Solution Structure of a Conformationally Restricted Fully Active Derivative of the Human Relaxin-like Factor (RLF) | 分子名称: | Insulin-like 3 A chain, Insulin-like 3 B chain | 著者 | Bullesbach, E.E, Hass, M.A.S, Jensen, M.R, Hansen, D.F, Kristensen, S.M, Schwabe, C, Led, J.J. | 登録日 | 2008-07-24 | 公開日 | 2008-12-16 | 最終更新日 | 2021-11-10 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a conformationally restricted fully active derivative of the human relaxin-like factor Biochemistry, 47, 2008
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2K6T
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![BU of 2k6t by Molmil](/molmil-images/mine/2k6t) | Solution structure of the relaxin-like factor | 分子名称: | Insulin-like 3 A chain, Insulin-like 3 B chain | 著者 | Bullesbach, E.E, Hass, M.A.S, Jensen, M.R, Hansen, D.F, Kristensen, S.M, Schwabe, C, Led, J.J. | 登録日 | 2008-07-23 | 公開日 | 2008-12-16 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a conformationally restricted fully active derivative of the human relaxin-like factor Biochemistry, 47, 2008
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