3C5V
 
 | | PP2A-specific methylesterase apo form (PME) | | Descriptor: | Protein phosphatase methylesterase 1 | | Authors: | Xing, Y, Li, Z, Chen, Y, Stock, J, Jeffrey, P.D, Shi, Y. | | Deposit date: | 2008-02-01 | | Release date: | 2008-04-15 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural mechanism of demethylation and inactivation of protein phosphatase 2A.
Cell(Cambridge,Mass.), 133, 2008
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1SHX
 | | Ephrin A5 ligand structure | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin-A5 | | Authors: | Himanen, J.P, Barton, W.A, Nikolov, D.B, Jeffrey, P.D. | | Deposit date: | 2004-02-26 | | Release date: | 2005-04-19 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Three distinct molecular surfaces in ephrin-A5 are essential for a functional interaction with EphA3.
J.Biol.Chem., 280, 2005
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8DIT
 | | Cryo-EM structure of a HOPS core complex containing Vps33, Vps16, and Vps18 | | Descriptor: | Vacuolar protein sorting-associated protein 16, Vacuolar protein sorting-associated protein 18, Vacuolar protein sorting-associated protein 33 | | Authors: | Port, S.A, Farrell, P.D, Jeffrey, P.D, DiMaio, F, Hughson, F.M. | | Deposit date: | 2022-06-29 | | Release date: | 2022-08-31 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (5.1 Å) | | Cite: | Cryo-EM structure of the HOPS core complex and its implication for SNARE assembly
To Be Published
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7LTB
 | | Crystal Structure of Keratinicyclin B | | Descriptor: | (2~{S},4~{S},5~{R},6~{S})-4-azanyl-5-methoxy-6-methyl-oxan-2-ol, 3-ammonio-2,3,6-trideoxy-alpha-L-arabino-hexopyranose-(1-2)-beta-D-glucopyranose, FORMIC ACID, ... | | Authors: | Davis, K.M, Jeffrey, P.D, Seyedsayamdost, M.R. | | Deposit date: | 2021-02-19 | | Release date: | 2022-12-07 | | Last modified: | 2024-07-24 | | Method: | X-RAY DIFFRACTION (0.95 Å) | | Cite: | Potent and specific antibiotic combination therapy against Clostridioides difficile.
Nat.Chem.Biol., 20, 2024
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7LKC
 | | Crystal Structure of Keratinimicin A | | Descriptor: | (2~{S},4~{S},5~{R},6~{S})-4-azanyl-5-methoxy-6-methyl-oxan-2-ol, CHLORIDE ION, FORMIC ACID, ... | | Authors: | Davis, K.M, Jeffrey, P.D, Seyedsayamdost, M.R. | | Deposit date: | 2021-02-02 | | Release date: | 2022-12-07 | | Last modified: | 2024-07-24 | | Method: | X-RAY DIFFRACTION (0.95 Å) | | Cite: | Potent and specific antibiotic combination therapy against Clostridioides difficile.
Nat.Chem.Biol., 20, 2024
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7N29
 | | Structure of NAD kinase | | Descriptor: | NAD kinase 2, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Du, J, Estrella, M.A, Jeffrey, P.D, Korennykh, A.V. | | Deposit date: | 2021-05-28 | | Release date: | 2022-05-04 | | Last modified: | 2022-06-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of human NADK2 reveals atypical assembly and regulation of NAD kinases from animal mitochondria.
Proc.Natl.Acad.Sci.USA, 119, 2022
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8FTU
 | | Crystal structure of the SNARE Use1 bound to Dsl1 complex subunits Sec39 and Dsl1, Revised Use1 structure | | Descriptor: | Protein transport protein DSL1, Protein transport protein SEC39, Vesicle transport protein USE1 | | Authors: | Travis, S.M, Jeffrey, P.D, Hughson, F.M. | | Deposit date: | 2023-01-13 | | Release date: | 2023-03-01 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (5.73 Å) | | Cite: | Structure of a membrane tethering complex incorporating multiple SNAREs.
Nat.Struct.Mol.Biol., 31, 2024
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8CUK
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8EKI
 | | CryoEM structure of the Dsl1 complex bound to SNAREs Sec20 and Use1 | | Descriptor: | Protein transport protein DSL1, Protein transport protein SEC20, Protein transport protein SEC39, ... | | Authors: | DAmico, K.A, Jeffrey, P.D, Hughson, F.M. | | Deposit date: | 2022-09-21 | | Release date: | 2023-10-04 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structure of a membrane tethering complex incorporating multiple SNAREs.
Nat.Struct.Mol.Biol., 31, 2024
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6UFF
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