5RMF
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![BU of 5rmf by Molmil](/molmil-images/mine/5rmf) | PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 helicase in complex with Z54226006 | 分子名称: | (2,6-difluorophenyl)(pyrrolidin-1-yl)methanone, Helicase, PHOSPHATE ION, ... | 著者 | Newman, J.A, Yosaatmadja, Y, Douangamath, A, Aimon, A, Powell, A.J, Dias, A, Fearon, D, Dunnett, L, Brandao-Neto, J, Krojer, T, Skyner, R, Gorrie-Stone, T, Thompson, W, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2020-09-16 | 公開日 | 2020-09-30 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase. Nat Commun, 12, 2021
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5RYT
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![BU of 5ryt by Molmil](/molmil-images/mine/5ryt) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z54226006 | 分子名称: | (2,6-difluorophenyl)(pyrrolidin-1-yl)methanone, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... | 著者 | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | 登録日 | 2020-10-30 | 公開日 | 2020-11-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | EPB41L3 PanDDA analysis group deposition To Be Published
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5RZ5
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![BU of 5rz5 by Molmil](/molmil-images/mine/5rz5) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z2856434851 | 分子名称: | 1,2-ETHANEDIOL, 4-({[(4-fluorophenyl)methyl]amino}methyl)benzonitrile, DIMETHYL SULFOXIDE, ... | 著者 | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | 登録日 | 2020-10-30 | 公開日 | 2020-11-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | EPB41L3 PanDDA analysis group deposition To Be Published
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5RZG
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![BU of 5rzg by Molmil](/molmil-images/mine/5rzg) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z133729708 | 分子名称: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Isoform 2 of Band 4.1-like protein 3, ... | 著者 | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | 登録日 | 2020-10-30 | 公開日 | 2020-11-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | EPB41L3 PanDDA analysis group deposition To Be Published
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5RZW
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![BU of 5rzw by Molmil](/molmil-images/mine/5rzw) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z2574937229 | 分子名称: | (S)-1-(4-methoxyphenyl)-1-phenylmethanamine, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... | 著者 | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | 登録日 | 2020-10-30 | 公開日 | 2020-11-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | EPB41L3 PanDDA analysis group deposition To Be Published
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5RZ6
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![BU of 5rz6 by Molmil](/molmil-images/mine/5rz6) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z2856434944 | 分子名称: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Isoform 2 of Band 4.1-like protein 3, ... | 著者 | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | 登録日 | 2020-10-30 | 公開日 | 2020-11-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | EPB41L3 PanDDA analysis group deposition To Be Published
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5RZM
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![BU of 5rzm by Molmil](/molmil-images/mine/5rzm) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z2856434815 | 分子名称: | 1,2-ETHANEDIOL, 4-[(dimethylamino)methyl]benzonitrile, DIMETHYL SULFOXIDE, ... | 著者 | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | 登録日 | 2020-10-30 | 公開日 | 2020-11-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | EPB41L3 PanDDA analysis group deposition To Be Published
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5ROB
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![BU of 5rob by Molmil](/molmil-images/mine/5rob) | PanDDA analysis group deposition of ground-state model of SARS-CoV-2 helicase | 分子名称: | Helicase, PHOSPHATE ION, ZINC ION | 著者 | Newman, J.A, Yosaatmadja, Y, Douangamath, A, Aimon, A, Powell, A.J, Dias, A, Fearon, D, Dunnett, L, Brandao-Neto, J, Krojer, T, Skyner, R, Gorrie-Stone, T, Thompson, W, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2020-09-22 | 公開日 | 2021-03-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | PanDDA analysis group deposition of ground-state model To Be Published
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1IKG
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![BU of 1ikg by Molmil](/molmil-images/mine/1ikg) | MICHAELIS COMPLEX OF STREPTOMYCES R61 DD-PEPTIDASE WITH A SPECIFIC PEPTIDOGLYCAN SUBSTRATE FRAGMENT | 分子名称: | D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, GLYCYL-L-ALPHA-AMINO-EPSILON-PIMELYL-D-ALANYL-D-ALANINE | 著者 | Mcdonough, M.A, Anderson, J.W, Silvaggi, N.R, Pratt, R.F, Knox, J.R, Kelly, J.A. | 登録日 | 2001-05-03 | 公開日 | 2002-09-11 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of two kinetic intermediates reveal species specificity of penicillin-binding proteins. J.Mol.Biol., 322, 2002
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1O9A
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![BU of 1o9a by Molmil](/molmil-images/mine/1o9a) | Solution structure of the complex of 1F12F1 from fibronectin with B3 from FnBB from S. dysgalactiae | 分子名称: | FIBRONECTIN, FIBRONECTIN BINDING PROTEIN | 著者 | Schwarz-Linek, U, Werner, J.M, Pickford, A.R, Pilka, E.S, Gurusiddappa, S, Briggs, J.A.G, Hook, M, Campbell, I.D, Potts, J.R. | 登録日 | 2002-12-11 | 公開日 | 2003-05-08 | 最終更新日 | 2018-01-24 | 実験手法 | SOLUTION NMR | 主引用文献 | Pathogenic bacteria attach to human fibronectin through a tandem beta-zipper. Nature, 423, 2003
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3N3A
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![BU of 3n3a by Molmil](/molmil-images/mine/3n3a) | Ribonucleotide Reductase Dimanganese(II)-NrdF from Escherichia coli in Complex with Reduced NrdI | 分子名称: | FLAVIN MONONUCLEOTIDE, MANGANESE (II) ION, Protein nrdI, ... | 著者 | Boal, A.K, Cotruvo Jr, J.A, Stubbe, J, Rosenzweig, A.C. | 登録日 | 2010-05-19 | 公開日 | 2010-08-18 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structural basis for activation of class Ib ribonucleotide reductase. Science, 329, 2010
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3N39
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![BU of 3n39 by Molmil](/molmil-images/mine/3n39) | Ribonucleotide Reductase Dimanganese(II)-NrdF from Escherichia coli in Complex with NrdI | 分子名称: | FLAVIN MONONUCLEOTIDE, MANGANESE (II) ION, Protein nrdI, ... | 著者 | Boal, A.K, Cotruvo Jr, J.A, Stubbe, J, Rosenzweig, A.C. | 登録日 | 2010-05-19 | 公開日 | 2010-08-18 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for activation of class Ib ribonucleotide reductase. Science, 329, 2010
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5UCF
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![BU of 5ucf by Molmil](/molmil-images/mine/5ucf) | Solution NMR-derived model of the minor species of DANCER-2, a dynamic and natively folded pentamutant of the B1 domain of streptococcal protein G (GB1) | 分子名称: | Immunoglobulin G-binding protein G | 著者 | Damry, A.M, Davey, J.A, Goto, N.K, Chica, R.A. | 登録日 | 2016-12-22 | 公開日 | 2017-08-23 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Rational design of proteins that exchange on functional timescales. Nat. Chem. Biol., 13, 2017
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5UB0
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![BU of 5ub0 by Molmil](/molmil-images/mine/5ub0) | Solution NMR Structure of NERD-C, a natively folded tetramutant of the B1 domain of streptococcal protein G (GB1) | 分子名称: | Immunoglobulin G-binding protein G | 著者 | Damry, A.M, Davey, J.A, Goto, N.K, Chica, R.A. | 登録日 | 2016-12-20 | 公開日 | 2017-08-23 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Rational design of proteins that exchange on functional timescales. Nat. Chem. Biol., 13, 2017
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5UIB
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![BU of 5uib by Molmil](/molmil-images/mine/5uib) | Crystal Structure of an Oxidoreductase from Agrobacterium radiobacter in Complex with NAD+, L-tartaric acid and Magnesium | 分子名称: | L(+)-TARTARIC ACID, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Cook, W.J, Fedorov, A.A, Fedorov, E.V, Huang, H, Bonanno, J.B, Gerlt, J.A, Almo, S.C. | 登録日 | 2017-01-13 | 公開日 | 2017-01-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Crystal Structure of an Oxidoreductase from Agrobacterium radiobacter in Complex with NAD+, L-tartaric acid and Magnesium To be published
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5UIA
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![BU of 5uia by Molmil](/molmil-images/mine/5uia) | Crystal Structure of an Oxidoreductase from Agrobacterium radiobacter in Complex with NAD+, R-2,3-dihydroxyisovalerate and Magnesium | 分子名称: | (2S)-2,3-dihydroxy-3-methylbutanoic acid, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Cook, W.J, Fedorov, A.A, Fedorov, E.V, Huang, H, Bonanno, J.B, Gerlt, J.A, Almo, S.C. | 登録日 | 2017-01-13 | 公開日 | 2017-02-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Crystal Structure of an Oxidoreductase from Agrobacterium radiobacter in Complex with NAD+, R-2,3-dihydroxyisovalerate and Magnesium To be published
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5D6P
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![BU of 5d6p by Molmil](/molmil-images/mine/5d6p) | Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1-ethyl-3-[4-(hydroxymethyl)-5-(1H-pyrrol-2-yl)-1,3-thiazol-2-yl]urea, DNA gyrase subunit B, ... | 著者 | Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C. | 登録日 | 2015-08-12 | 公開日 | 2015-11-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors. J.Med.Chem., 58, 2015
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5UOO
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![BU of 5uoo by Molmil](/molmil-images/mine/5uoo) | BRD4 bromodomain 2 in complex with CD161 | 分子名称: | 7-(3,5-dimethyl-1,2-oxazol-4-yl)-6-methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indole, Bromodomain-containing protein 4 | 著者 | Meagher, J.L, Stuckey, J.A. | 登録日 | 2017-02-01 | 公開日 | 2017-05-17 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor. J. Med. Chem., 60, 2017
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5U8U
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![BU of 5u8u by Molmil](/molmil-images/mine/5u8u) | Dihydrolipoamide dehydrogenase (LpdG) from Pseudomonas aeruginosa | 分子名称: | DIMETHYL SULFOXIDE, Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Glasser, N.R, Wang, B.X, Hoy, J.A, Newman, D.K. | 登録日 | 2016-12-15 | 公開日 | 2017-02-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | The Pyruvate and alpha-Ketoglutarate Dehydrogenase Complexes of Pseudomonas aeruginosa Catalyze Pyocyanin and Phenazine-1-carboxylic Acid Reduction via the Subunit Dihydrolipoamide Dehydrogenase. J. Biol. Chem., 292, 2017
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3N5F
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![BU of 3n5f by Molmil](/molmil-images/mine/3n5f) | Crystal Structure of L-N-carbamoylase from Geobacillus stearothermophilus CECT43 | 分子名称: | CACODYLATE ION, COBALT (II) ION, ISOPROPYL ALCOHOL, ... | 著者 | Garcia-Pino, A, Martinez-Rodriguez, S, Gavira, J.A. | 登録日 | 2010-05-25 | 公開日 | 2011-05-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Mutational and structural analysis of L-N-carbamoylase reveals new insights into a peptidase m20/m25/m40 family member. J.Bacteriol., 194, 2012
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5U9T
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![BU of 5u9t by Molmil](/molmil-images/mine/5u9t) | The Tris-thiolate Zn(II)S3Cl Binding Site Engineered by D-Cysteine Ligands in de Novo Three-stranded Coiled Coil Environment | 分子名称: | ACETATE ION, CHLORIDE ION, POLYETHYLENE GLYCOL (N=34), ... | 著者 | Ruckthong, L, Peacock, A.F.A, Stuckey, J.A, Pecoraro, V.L. | 登録日 | 2016-12-18 | 公開日 | 2017-04-26 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | d-Cysteine Ligands Control Metal Geometries within De Novo Designed Three-Stranded Coiled Coils. Chemistry, 23, 2017
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1NWW
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![BU of 1nww by Molmil](/molmil-images/mine/1nww) | Limonene-1,2-epoxide hydrolase | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HEPTANAMIDE, Limonene-1,2-epoxide hydrolase | 著者 | Arand, M, Hallberg, B.M, Zou, J, Bergfors, T, Oesch, F, van der Werf, M.J, de Bont, J.A.M, Jones, T.A, Mowbray, S.L. | 登録日 | 2003-02-07 | 公開日 | 2003-06-10 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active site EMBO J., 22, 2003
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5UFQ
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![BU of 5ufq by Molmil](/molmil-images/mine/5ufq) | K-RasG12D(GNP)/R11.1.6 complex | 分子名称: | CADMIUM ION, CALCIUM ION, CHLORIDE ION, ... | 著者 | Parker, J.A, Mattos, C. | 登録日 | 2017-01-05 | 公開日 | 2017-08-02 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | 主引用文献 | An engineered protein antagonist of K-Ras/B-Raf interaction. Sci Rep, 7, 2017
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5UHW
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![BU of 5uhw by Molmil](/molmil-images/mine/5uhw) | Crystal Structure of an Oxidoreductase from Agrobacterium radiobacter in Complex with NAD+ and Magnesium | 分子名称: | MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Oxidoreductase protein | 著者 | Cook, W.J, Fedorov, A.A, Fedorov, E.V, Huang, H, Bonanno, J.B, Gerlt, J.A, Almo, S.C. | 登録日 | 2017-01-12 | 公開日 | 2017-01-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Crystal Structure of an Oxidoreductase from Agrobacterium radiobacter in Complex with NAD+ and Magnesium To be published
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5UHZ
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![BU of 5uhz by Molmil](/molmil-images/mine/5uhz) | Crystal Structure of an Oxidoreductase from Agrobacterium radiobacter in Complex with NAD+, D-Apionate and Magnesium | 分子名称: | (3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-one, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Cook, W.J, Fedorov, A.A, Fedorov, E.V, Huang, H, Bonanno, J.B, Gerlt, J.A, Almo, S.C. | 登録日 | 2017-01-12 | 公開日 | 2017-02-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of an Oxidoreductase from Agrobacterium radiobacter in Complex with NAD+, D-Apionate and Magnesium To be published
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