1B6L
| HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 4 | 分子名称: | 1-[2-(8-CARBAMOYLMETHYL-6,9-DIOXO-2-OXA-7,10-DIAZA-BICYCLO[11.2.2]HEPTADECA- 1(16),13(17),14-TRIEN-11-YL)-2-HYDROXY-ETHYL]-PIPERIDINE-2-CARBOXYLIC ACID TERT-BUTYLAMIDE, RETROPEPSIN, SULFATE ION | 著者 | Martin, J.L, Begun, J, Schindeler, A, Wickramasinghe, W.A, Alewood, D, Alewood, P.F, Bergman, D.A, Brinkworth, R.I, Abbenante, G, March, D.R, Reid, R.C, Fairlie, D.P. | 登録日 | 1999-01-17 | 公開日 | 2000-01-07 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease. Biochemistry, 38, 1999
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4CRC
| Creating novel F1 inhibitors through fragment based lead generation and structure aided drug design | 分子名称: | (2S)-2-[[(E)-3-[5-chloranyl-2-(1,2,3,4-tetrazol-1-yl)phenyl]prop-2-enoyl]amino]-3-phenyl-N-[4-(1H-1,2,3,4-tetrazol-5-yl)phenyl]propanamide, COAGULATION FACTOR XI, SULFATE ION | 著者 | Sandmark, J, Oster, L, Fjellstrom, O, Akkaya, S, Beisel, H.G, Eriksson, P.O, Erixon, K, Gustafsson, D, Jurva, U, Kang, D, Karis, D, Knecht, W, Nerme, V, Nilsson, I, Olsson, T, Redzic, A, Roth, R, Tigerstrom, A. | 登録日 | 2014-02-26 | 公開日 | 2015-02-11 | 最終更新日 | 2015-08-19 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Creating Novel Activated Factor Xi Inhibitors Through Fragment Based Lead Generation and Structure Aided Drug Design. Plos One, 10, 2015
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1XTZ
| Crystal structure of the S. cerevisiae D-ribose-5-phosphate isomerase: comparison with the archeal and bacterial enzymes | 分子名称: | Ribose-5-phosphate isomerase | 著者 | Graille, M, Meyer, P, Leulliot, N, Sorel, I, Janin, J, van Tilbeurgh, H, Quevillon-Cheruel, S. | 登録日 | 2004-10-25 | 公開日 | 2005-08-30 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of the S. cerevisiae D-ribose-5-phosphate isomerase: comparison with the archaeal and bacterial enzymes Biochimie, 87, 2005
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1B7D
| NEUROTOXIN (TS1) FROM BRAZILIAN SCORPION TITYUS SERRULATUS | 分子名称: | PHOSPHATE ION, PROTEIN (NEUROTOXIN TS1) | 著者 | Polikarpov, I, Sanches Jr, M.S, Marangoni, S, Toyama, M.H, Teplyakov, A. | 登録日 | 1999-01-21 | 公開日 | 1999-07-22 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Crystal structure of neurotoxin Ts1 from Tityus serrulatus provides insights into the specificity and toxicity of scorpion toxins. J.Mol.Biol., 290, 1999
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4CN4
| GlgE isoform 1 from Streptomyces coelicolor E423A mutant with 2-deoxy- 2-fluoro-beta-maltosyl modification | 分子名称: | ALPHA-1,4-GLUCAN:MALTOSE-1-PHOSPHATE MALTOSYLTRANSFERASE 1, alpha-D-glucopyranose-(1-4)-2-deoxy-2-fluoro-beta-D-glucopyranose | 著者 | Syson, K, Stevenson, C.E.M, Rashid, A.M, Saalbach, G, Tang, M, Tuukanen, A, Svergun, D.I, Withers, S.G, Lawson, D.M, Bornemann, S. | 登録日 | 2014-01-21 | 公開日 | 2014-05-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural Insight Into How Streptomyces Coelicolor Maltosyl Transferase Glge Binds Alpha-Maltose 1-Phosphate and Forms a Maltosyl-Enzyme Intermediate. Biochemistry, 53, 2014
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1BAI
| Crystal structure of Rous sarcoma virus protease in complex with inhibitor | 分子名称: | N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide, PROTEASE | 著者 | Wu, J, Adomat, J.M, Ridky, T.W, Louis, J.M, Leis, J, Harrison, R.W, Weber, I.T. | 登録日 | 1998-04-17 | 公開日 | 1999-01-13 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for specificity of retroviral proteases. Biochemistry, 37, 1998
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1XFT
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1BBT
| METHODS USED IN THE STRUCTURE DETERMINATION OF FOOT AND MOUTH DISEASE VIRUS | 分子名称: | FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1), FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP2), FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP3), ... | 著者 | Acharya, K.R, Fry, E.E, Logan, D.T, Stuart, D.I. | 登録日 | 1992-05-18 | 公開日 | 1994-01-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Methods used in the structure determination of foot-and-mouth disease virus. Acta Crystallogr.,Sect.A, 49, 1993
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1XIL
| HYDROGEN BONDING IN HUMAN MANGANESE SUPEROXIDE DISMUTASE CONTAINING 3-FLUOROTYROSINE | 分子名称: | MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial | 著者 | Ayala, I, Perry, J.J, Szczepanski, J, Cabelli, D.E, Tainer, J.A, Vala, M.T, Nick, H.S, Silverman, D.N. | 登録日 | 2004-09-21 | 公開日 | 2005-03-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Hydrogen bonding in human manganese superoxide dismutase containing 3-fluorotyrosine Biophys.J., 89, 2005
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1XKS
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1XLO
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1B6I
| T4 LYSOZYME MUTANT WITH CYS 54 REPLACED BY THR, CYS 97 REPLACED BY ALA, THR 21 REPLACED BY CYS AND LYS 124 REPLACED BY CYS (C54T,C97A,T21C,K124C) | 分子名称: | 2-HYDROXYETHYL DISULFIDE, PROTEIN (LYSOZYME) | 著者 | Vetter, I.R, Baase, W.A, Snow, S, Matthews, B.W. | 登録日 | 1999-01-14 | 公開日 | 2000-01-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Solid-state synthesis and mechanical unfolding of polymers of T4 lysozyme. Proc.Natl.Acad.Sci.USA, 97, 2000
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1XRN
| Crystal structure of active site F1-mutant E213Q soaked with peptide Phe-Ala | 分子名称: | ALANINE, Proline iminopeptidase | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | 登録日 | 2004-10-15 | 公開日 | 2005-07-12 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
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1XRR
| Crystal structure of active site F1-mutant E245Q soaked with peptide Pro-Pro | 分子名称: | PROLINE, Proline iminopeptidase | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | 登録日 | 2004-10-15 | 公開日 | 2005-07-12 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
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1XVQ
| Crystal structure of thiol peroxidase from Mycobacterium tuberculosis | 分子名称: | AMMONIUM ION, YTTRIUM (III) ION, thiol peroxidase | 著者 | Rho, B.S, Pedelacq, J.D, Hung, L.W, Holton, J.M, Vigil, D, Kim, S.I, Park, M.S, Terwilliger, T.C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2004-10-28 | 公開日 | 2004-12-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Functional and Structural Characterization of a Thiol Peroxidase from Mycobacterium tuberculosis. J.Mol.Biol., 361, 2006
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4LKA
| Crystal Structure of MOZ double PHD finger histone H3K9ac complex | 分子名称: | Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION | 著者 | Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M. | 登録日 | 2013-07-07 | 公開日 | 2013-10-16 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification. Nucleic Acids Res., 42, 2014
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1F22
| A PROTON-NMR INVESTIGATION OF THE FULLY REDUCED CYTOCHROME C7 FROM DESULFUROMONAS ACETOXIDANS. COMPARISON BETWEEN THE REDUCED AND THE OXIDIZED FORMS. | 分子名称: | CYTOCHROME C7, HEME C | 著者 | Assfalg, M, Banci, L, Bertini, I, Bruschi, M, Giudici-Orticoni, M.T. | 登録日 | 2000-05-23 | 公開日 | 2000-06-21 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | A proton-NMR investigation of the fully reduced cytochrome c7 from Desulfuromonas acetoxidans. Comparison between the reduced and the oxidized forms. Eur.J.Biochem., 266, 1999
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1F0U
| BOVINE TRYPSIN COMPLEXED WITH RPR128515 | 分子名称: | 3-[(3'-AMINOMETHYL-BIPHENYL-4-CARBONYL)-AMINO]-2-(3-CARBAMIMIDOYL-BENZYL)-BUTYRIC ACID METHYL ESTER, CALCIUM ION, SULFATE ION, ... | 著者 | Maignan, S, Guilloteau, J.P, Pouzieux, S, Choi-Sledeski, Y.M, Becker, M.R, Klein, S.I, Ewing, W.R, Pauls, H.W, Spada, A.P, Mikol, V. | 登録日 | 2000-05-17 | 公開日 | 2000-09-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of human factor Xa complexed with potent inhibitors. J.Med.Chem., 43, 2000
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1X8E
| Crystal structure of Pyrococcus furiosus phosphoglucose isomerase free enzyme | 分子名称: | Glucose-6-phosphate isomerase | 著者 | Berrisford, J.M, Akerboom, J, Brouns, S, Sedelnikova, S.E, Turnbull, A.P, van der Oost, J, Salmon, L, Hardre, R, Murray, I.A, Blackburn, G.M, Rice, D.W, Baker, P.J. | 登録日 | 2004-08-18 | 公開日 | 2004-10-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis. J.Mol.Biol., 343, 2004
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1XHH
| Solution Structure of porcine beta-microseminoprotein | 分子名称: | beta-microseminoprotein | 著者 | Wang, I, Lou, Y.C, Wu, K.P, Wu, S.H, Chang, W.C, Chen, C. | 登録日 | 2004-09-20 | 公開日 | 2005-03-20 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Novel solution structure of porcine beta-microseminoprotein J.Mol.Biol., 346, 2005
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4CRA
| Creating novel F1 inhibitors through fragment based lead generation and structure aided drug design | 分子名称: | COAGULATION FACTOR XI, GLYCEROL, N-[(1S)-2-[(2-amino-5-quinolyl)methylamino]-1-benzyl-2-oxo-ethyl]-4-hydroxy-2-oxo-1H-quinoline-6-carboxamide, ... | 著者 | Sandmark, J, Oster, L, Fjellstrom, O, Akkaya, S, Beisel, H.G, Eriksson, P.O, Erixon, K, Gustafsson, D, Jurva, U, Kang, D, Karis, D, Knecht, W, Nerme, V, Nilsson, I, Olsson, T, Redzic, A, Roth, R, Tigerstrom, A. | 登録日 | 2014-02-26 | 公開日 | 2015-02-11 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Creating Novel Activated Factor Xi Inhibitors Through Fragment Based Lead Generation and Structure Aided Drug Design. Plos One, 10, 2015
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1F5U
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4CRD
| Creating novel F1 inhibitors through fragment based lead generation and structure aided drug design | 分子名称: | COAGULATION FACTOR XI, Methyl N-[4-[5-chloro-2-[[3-[5-chloro-2-(tetrazol-1-yl)phenyl]propanoylamino]methyl]-1H-imidazol-4-yl]phenyl]carbamate, SULFATE ION | 著者 | Sandmark, J, Oster, L, Fjellstrom, O, Akkaya, S, Beisel, H.G, Eriksson, P.O, Erixon, K, Gustafsson, D, Jurva, U, Kang, D, Karis, D, Knecht, W, Nerme, V, Nilsson, I, Olsson, T, Redzic, A, Roth, R, Tigerstrom, A. | 登録日 | 2014-02-26 | 公開日 | 2015-02-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Creating Novel Activated Factor Xi Inhibitors Through Fragment Based Lead Generation and Structure Aided Drug Design. Plos One, 10, 2015
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1XQY
| Crystal structure of F1-mutant S105A complex with PRO-LEU-GLY-GLY | 分子名称: | PLGG, PROLINE, Proline iminopeptidase | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | 登録日 | 2004-10-13 | 公開日 | 2005-07-12 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
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4CN6
| GlgE isoform 1 from Streptomyces coelicolor E423A mutant with maltose bound | 分子名称: | ALPHA-1,4-GLUCAN:MALTOSE-1-PHOSPHATE MALTOSYLTRANSFERASE 1, alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Syson, K, Stevenson, C.E.M, Rashid, A.M, Saalbach, G, Tang, M, Tuukanen, A, Svergun, D.I, Withers, S.G, Lawson, D.M, Bornemann, S. | 登録日 | 2014-01-21 | 公開日 | 2014-05-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Structural Insight Into How Streptomyces Coelicolor Maltosyl Transferase Glge Binds Alpha-Maltose 1-Phosphate and Forms a Maltosyl-Enzyme Intermediate. Biochemistry, 53, 2014
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