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PDB: 73 件
4JBJ
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Structural mimicry for functional antagonism
分子名称: Interferon-activable protein 202
著者Ru, H, Ni, X, Ma, F, Zhao, L, Ding, W, Hung, L.-W, Shaw, N, Cheng, G, Liu, Z.-J.
登録日2013-02-19
公開日2013-06-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.692 Å)
主引用文献Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
4JBK
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BU of 4jbk by Molmil
Molecular basis for abrogation of activation of pro-inflammatory cytokines
分子名称: DNA (5'-D(P*GP*GP*AP*AP*TP*TP*AP*TP*AP*AP*TP*TP*CP*C)-3'), Interferon-activable protein 202
著者Ru, H, Ni, X, Crowley, C, Zhao, L, Ding, W, Hung, L.-W, Shaw, N, Cheng, G, Liu, Z.-J.
登録日2013-02-19
公開日2013-06-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.963 Å)
主引用文献Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
7WLS
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BU of 7wls by Molmil
Crystal structure of the multidrug efflux transporter BpeB from Burkholderia pseudomallei
分子名称: Efflux pump membrane transporter, TETRAETHYLENE GLYCOL, UNDECYL-MALTOSIDE
著者Kato, T, Hung, L.-W, Yamashita, E, Okada, U, Terwilliger, T.C, Murakami, S.
登録日2022-01-13
公開日2023-07-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Crystal structures of multidrug efflux transporters from Burkholderia pseudomallei suggest details of transport mechanism.
Proc.Natl.Acad.Sci.USA, 120, 2023
1EIF
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BU of 1eif by Molmil
EUKARYOTIC TRANSLATION INITIATION FACTOR 5A FROM METHANOCOCCUS JANNASCHII
分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 5A
著者Kim, K.K, Hung, L.W, Yokota, H, Kim, R, Kim, S.H.
登録日1998-07-29
公開日1998-10-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of eukaryotic translation initiation factor 5A from Methanococcus jannaschii at 1.8 A resolution.
Proc.Natl.Acad.Sci.USA, 95, 1998
4FN8
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BU of 4fn8 by Molmil
Crystal structure of the Mtb enoyl CoA isomerase (Rv0632c)in complex with acetoacetyl CoA
分子名称: ACETOACETYL-COENZYME A, Enoyl-CoA hydratase/isomerase family protein, SULFATE ION
著者Bruning, J.B, Gao, N, Hernandez, E.D, Li, H, Dang, N, Hung, L.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2012-06-19
公開日2013-05-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.831 Å)
主引用文献Crystal structure and mechanism of the prokaryotic enoyl CoA isomerase (ECI)
To be Published
4FNB
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Crystal structure of the Mtb enoyl CoA isomerase (Rv0632c) in complex with hydroxybutyrl CoA
分子名称: 3-HYDROXYBUTANOYL-COENZYME A, Enoyl-CoA hydratase/isomerase family protein, SULFATE ION
著者Bruning, J.B, Gao, N, Hernandez, E.D, Li, H, Dang, N, Hung, L.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2012-06-19
公開日2013-05-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure and Mechanism of the Prokaryotic Enoyl CoA Isomerase
To be Published
4FND
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Crystal structure of the Mtb enoyl CoA isomerase in complex with hydroxyhexanoyl CoA
分子名称: (S)-3-Hydroxyhexanoyl-CoA, Enoyl-CoA hydratase/isomerase family protein, SULFATE ION
著者Bruning, J.B, Gao, N, Hernandez, E.D, Li, H, Dang, N, Hung, L.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2012-06-19
公開日2013-05-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure and mechanism of the prokaryotic enoyl CoA isomerase
To be Published
4FN7
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Apo Structure of the Mtb enoyol CoA isomerase (Rv0632c)
分子名称: CHLORIDE ION, Enoyl-CoA hydratase/isomerase family protein
著者Bruning, J.B, Gao, N, Hernandez, E.D, Li, H, Dang, N, Hung, L.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2012-06-19
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献"Crystal Structure and Mechanism of the Prokaryotic Enoyl-CoA Isomerase (ECI)"
To be Published
4LMP
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BU of 4lmp by Molmil
Mycobacterium tuberculosis L-alanine dehydrogenase x-ray structure in complex with N6-methyl adenosine
分子名称: Alanine dehydrogenase, GLYCEROL, N-methyladenosine, ...
著者Kim, H.-B, Hung, L.-W, Goulding, C.W, Terwilliger, T.C, Kim, C.-Y, Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI)
登録日2013-07-10
公開日2013-11-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Drug target analysis by dye-ligand affinity chromatography
To be Published
2G3S
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BU of 2g3s by Molmil
RNA structure containing GU base pairs
分子名称: 5'-R(*GP*GP*CP*GP*UP*GP*CP*C)-3', MAGNESIUM ION
著者Jang, S.B, Hung, L.W, Jeong, M.S, Holbrook, E.L, Chen, X, Turner, D.H, Holbrook, S.R.
登録日2006-02-20
公開日2007-01-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.499 Å)
主引用文献The crystal structure at 1.5 angstroms resolution of an RNA octamer duplex containing tandem G.U basepairs
Biophys.J., 90, 2006
4JJT
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The crystal structure of enoyl-CoA hydratase from Mycobacterium tuberculosis H37Rv
分子名称: ACETATE ION, Enoyl-CoA hydratase, GLYCEROL
著者Tan, K, Holowicki, J, Endres, M, Kim, C.-Y, Kim, H, Hung, L.-W, Terwilliger, T.C, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI)
登録日2013-03-08
公開日2013-03-27
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.496 Å)
主引用文献The crystal structure of enoyl-CoA hydratase from Mycobacterium tuberculosis H37Rv
To be Published
2NYX
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BU of 2nyx by Molmil
Crystal structure of RV1404 from Mycobacterium tuberculosis
分子名称: Probable transcriptional regulatory protein, Rv1404
著者Yu, M, Bursey, E.H, Radhakannan, R, Kim, C.-Y, Kaviratne, T, Woodruff, T, Segelke, B.W, Lekin, T, Toppani, D, Terwilliger, T.C, Hung, L.-W, TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI)
登録日2006-11-21
公開日2006-12-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of RV1404 from Mycobacterium tuberculosis
To be Published
2FSX
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BU of 2fsx by Molmil
Crystal structure of Rv0390 from M. tuberculosis
分子名称: BROMIDE ION, COG0607: Rhodanese-related sulfurtransferase, SULFATE ION
著者Bursey, E.H, Radhakannan, T, Yu, M, Segelke, B.W, Lekin, T, Toppani, D, Chang, Y.-B, Kaviratne, T, Woodruff, T, Terwilliger, T.C, Hung, L.-W, TB Structural Genomics Consortium (TBSGC)
登録日2006-01-23
公開日2006-02-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Rv0390 from Mycobacterium tuberculosis
To be Published
2H5X
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RuvA from Mycobacterium tuberculosis
分子名称: GLYCEROL, Holliday junction ATP-dependent DNA helicase ruvA
著者Prabu, J.R, Thamotharan, S, Khanduja, J.S, Alipio, E.Z, Kim, C.Y, Waldo, G.S, Terwilliger, T.C, Segelke, B, Lekin, T, Toppani, D, Hung, L.W, Yu, M, Bursey, E, Muniyappa, K, Chandra, N.R, Vijayan, M.
登録日2006-05-28
公開日2006-08-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of Mycobacterium tuberculosis RuvA, a protein involved in recombination.
ACTA CRYSTALLOGR.,SECT.F, 62, 2006
2IB0
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BU of 2ib0 by Molmil
Crystal structure of a conserved hypothetical protein, rv2844, from Mycobacterium tuberculosis
分子名称: CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN
著者Yu, M, Bursey, E.H, Radhakannan, T, Kim, C.Y, Kaviratne, T, Woodruff, T, Segelke, B.W, Lekin, T, Toppani, D, Terwilliger, T.C, Hung, L.W, TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI)
登録日2006-09-08
公開日2006-09-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a conserved hypothetical protein, rv2844, from Mycobacterium tuberculosis
To be Published
2FGG
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BU of 2fgg by Molmil
Crystal Structure of Rv2632c
分子名称: Hypothetical protein Rv2632c/MT2708
著者Yu, M, Bursey, E.H, Radhakannan, T, Segelke, B.W, Lekin, T, Toppani, D, Kim, C.Y, Kaviratne, T, Woodruff, T, Terwilliger, T.C, Hung, L.W, TB Structural Genomics Consortium (TBSGC)
登録日2005-12-21
公開日2006-02-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Rv2632c
To be Published
2G2D
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BU of 2g2d by Molmil
Crystal structure of a putative pduO-type ATP:cobalamin adenosyltransferase from Mycobacterium tuberculosis
分子名称: ATP:cobalamin adenosyltransferase
著者Moon, J.H, Kaviratne, A, Yu, M, Bursey, E.H, Hung, L.-W, Lekin, T.P, Segelke, B.W, Terwilliger, T.C, Kim, C.-Y, TB Structural Genomics Consortium (TBSGC)
登録日2006-02-15
公開日2006-03-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a putative pduO-type ATP:cobalamin adenosyltransferase from Mycobacterium tuberculosis.
To be Published
2GWR
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BU of 2gwr by Molmil
Crystal structure of the response regulator protein mtrA from Mycobacterium Tuberculosis
分子名称: CALCIUM ION, DNA-binding response regulator mtrA, GLYCEROL
著者Friedland, N, Mack, T.R, Yu, M, Bursey, E.H, Hung, L.W, Stock, A.M, Waldo, G.S, Terwilliger, T.C.
登録日2006-05-05
公開日2006-05-23
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Domain orientation in the inactive response regulator Mycobacterium tuberculosis MtrA provides a barrier to activation.
Biochemistry, 46, 2007
1ZVW
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The Crystal Structure of TrpD (Rv2192c) from Mycobacterium tuberculosis in Complex with PRPP and Magnesium
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, BENZAMIDINE, ...
著者Lee, C.E, Lott, J.S, Baker, E.N, Arcus, V.L, Javid-Majd, F, Goodfellow, C, Hung, L.-W, TB Structural Genomics Consortium (TBSGC)
登録日2005-06-02
公開日2006-01-17
最終更新日2021-08-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structure of TrpD, a Metabolic Enzyme Essential for Lung Colonization by Mycobacterium tuberculosis, in Complex with its Substrate Phosphoribosylpyrophosphate.
J.Mol.Biol., 355, 2006
3FY5
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Dishevelled PDZ domain homodimer
分子名称: Segment polarity protein dishevelled homolog DVL-2
著者Earnest, T, Friedland, N, Hung, L.-W, Moon, R.
登録日2009-01-21
公開日2009-09-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献

4JLP
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BU of 4jlp by Molmil
Crystal structure of R150K aquifex adenylate kinase mutant
分子名称: ADENOSINE-5'-DIPHOSPHATE, Adenylate kinase
著者Cho, Y.-J, Phung, L, Kern, D.
登録日2013-03-12
公開日2014-06-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.433 Å)
主引用文献The energy landscape of adenylate kinase during catalysis.
Nat.Struct.Mol.Biol., 22, 2015
4JLO
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BU of 4jlo by Molmil
Crystal structure of Aquifex adenylate kinase R150K mutant
分子名称: ADENOSINE-5'-DIPHOSPHATE, Adenylate kinase
著者Cho, Y.-J, Phung, L, Kern, D.
登録日2013-03-12
公開日2014-06-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献The energy landscape of adenylate kinase during catalysis.
Nat.Struct.Mol.Biol., 22, 2015
4CF7
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Crystal structure of adenylate kinase from Aquifex aeolicus with MgADP bound
分子名称: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENYLATE KINASE, ...
著者Kerns, S.J, Agafonov, R.V, Cho, Y.-J, Pontiggia, F, Otten, R, Pachov, D.V, Kutter, S, Phung, L.A, Murphy, P.N, Thai, V, Hagan, M.F, Kern, D.
登録日2013-11-13
公開日2014-12-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.594 Å)
主引用文献The Energy Landscape of Adenylate Kinase During Catalysis.
Nat.Struct.Mol.Biol., 22, 2015
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