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Structure of Human Anaplastic Lymphoma Kinase (ALK) harboring the G1202R/L1196M Compound Mutation in Complex with NVL-655
Descriptor:	ALK tyrosine kinase receptor, NVL-655
Authors:	Mente, S, Horan, J.C.
Deposit date:	2024-07-31
Release date:	2024-09-18
Last modified:	2024-10-02
Method:	X-RAY DIFFRACTION (1.58 Å)
Cite:	NVL-655 Is a Selective and Brain-Penetrant Inhibitor of Diverse ALK-Mutant Oncoproteins, Including Lorlatinib-Resistant Compound Mutations. Cancer Discov, 2024