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PDB: 74 件
6YJ5
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Focused refinement cryo-EM structure of the yeast mitochondrial complex I sub-stoichiometric sulfur transferase subunit
分子名称: Rhodanese-like domain-containing protein
著者Hirst, J, Grba, D.
登録日2020-04-02
公開日2020-08-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6YJ4
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Structure of Yarrowia lipolytica complex I at 2.7 A
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), Acyl carrier protein ACPM2 of NADH:Ubiquinone Oxidoreductase (Complex I), ...
著者Hirst, J, Grba, D.
登録日2020-04-02
公開日2020-08-12
最終更新日2021-03-17
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Mitochondrial complex I structure reveals ordered water molecules for catalysis and proton translocation.
Nat.Struct.Mol.Biol., 27, 2020
7B0N
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A 3.7-angstrom structure of Yarrowia lipolytica complex I with an R121M mutation in NUCM.
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, CARDIOLIPIN, ...
著者Hirst, J, Grba, D.
登録日2020-11-20
公開日2021-03-10
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献A conserved arginine residue is critical for stabilizing the N2 FeS cluster in mitochondrial complex I.
J.Biol.Chem., 296, 2021
1DJ1
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CRYSTAL STRUCTURE OF R48A MUTANT OF CYTOCHROME C PEROXIDASE
分子名称: CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE
著者Hirst, J, Goodin, D.B.
登録日1999-11-30
公開日1999-12-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Unusual oxidative chemistry of N(omega)-hydroxyarginine and N-hydroxyguanidine catalyzed at an engineered cavity in a heme peroxidase.
J.Biol.Chem., 275, 2000
1DSE
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CYTOCHROME C PEROXIDASE H175G MUTANT, IMIDAZOLE COMPLEX, WITH PHOSPHATE BOUND, PH 6, 100K
分子名称: CYTOCHROME C PEROXIDASE, IMIDAZOLE, PHOSPHATE ION, ...
著者Hirst, J, Wilcox, S.K, Williams, P.A, McRee, D.E, Goodin, D.B.
登録日2000-01-07
公開日2001-03-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure.
Biochemistry, 40, 2001
1DSO
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CYTOCHROME C PEROXIDASE H175G MUTANT, IMIDAZOLE COMPLEX AT PH 6, ROOM TEMPERATURE.
分子名称: CYTOCHROME C PEROXIDASE, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE
著者Hirst, J, Wilcox, S.K, Williams, P.A, McRee, D.E, Goodin, D.B.
登録日2000-01-07
公開日2001-03-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure.
Biochemistry, 40, 2001
1DS4
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CYTOCHROME C PEROXIDASE H175G MUTANT, IMIDAZOLE COMPLEX, PH 6, 100K
分子名称: CYTOCHROME C PEROXIDASE, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE
著者Hirst, J, Wilcox, S.K, Williams, P.A, McRee, D.E, Goodin, D.B.
登録日2000-01-07
公開日2001-03-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure.
Biochemistry, 40, 2001
1DSP
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CYTOCHROME C PEROXIDASE H175G MUTANT, IMIDAZOLE COMPLEX AT PH 7, ROOM TEMPERATURE.
分子名称: CYTOCHROME C PEROXIDASE, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE
著者Hirst, J, Wilcox, S.K, Williams, P.A, McRee, D.E, Goodin, D.B.
登録日2000-01-07
公開日2001-03-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure.
Biochemistry, 40, 2001
1DSG
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CYTOCHROME C PEROXIDASE H175G MUTANT, IMIDAZOLE COMPLEX AT PH 5, ROOM TEMPERATURE.
分子名称: CYTOCHROME C PEROXIDASE, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE
著者Hirst, J, Wilcox, S.K, Williams, P.A, McRee, D.E, Goodin, D.B.
登録日2000-01-07
公開日2001-03-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure.
Biochemistry, 40, 2001
1DJ5
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CRYSTAL STRUCTURE OF R48A MUTANT OF CYTOCHROME C PEROXIDASE WITH N-HYDROXYGUANIDINE BOUND
分子名称: CYTOCHROME C PEROXIDASE, N-HYDROXYGUANIDINE, PROTOPORPHYRIN IX CONTAINING FE
著者Hirst, J, Goodin, D.B.
登録日1999-12-01
公開日1999-12-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Unusual oxidative chemistry of N(omega)-hydroxyarginine and N-hydroxyguanidine catalyzed at an engineered cavity in a heme peroxidase.
J.Biol.Chem., 275, 2000
7PSA
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BU of 7psa by Molmil
The acetogenin-bound complex I of Mus musculus resolved to 3.4 angstroms
分子名称: (3~{S},5~{S})-5-methyl-3-[(13~{R})-13-oxidanyl-13-[(2~{R},5~{R})-5-[(2~{R},5~{R})-5-[(1~{R})-1-oxidanylundecyl]oxolan-2-yl]oxolan-2-yl]tridecyl]oxolan-2-one, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ...
著者Grba, D, Hirst, J.
登録日2021-09-22
公開日2022-04-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I.
J.Biol.Chem., 298, 2022
5O31
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Mitochondrial complex I in the deactive state
分子名称: Acyl carrier protein, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ...
著者Blaza, J.N, Vinothkumar, K.R, Hirst, J.
登録日2017-05-23
公開日2018-01-17
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (4.13 Å)
主引用文献Structure of the Deactive State of Mammalian Respiratory Complex I.
Structure, 26, 2018
5COD
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BU of 5cod by Molmil
Bovine heart complex I membrane domain
分子名称: NADH-ubiquinone oxidoreductase chain 4, NADH-ubiquinone oxidoreductase chain 5, SDAP, ...
著者Zhu, J, Hirst, J, King, M.S, Yu, M, Leslie, A.G.W, Klipcan, L.
登録日2015-07-20
公開日2015-09-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (6.74 Å)
主引用文献Structure of subcomplex I beta of mammalian respiratory complex I leads to new supernumerary subunit assignments.
Proc.Natl.Acad.Sci.USA, 112, 2015
4UQ8
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BU of 4uq8 by Molmil
Electron cryo-microscopy of bovine Complex I
分子名称: ACYL CARRIER PROTEIN, MITOCHONDRIAL, FE2/S2 (INORGANIC) CLUSTER, ...
著者Vinothkumar, K.R, Zhu, J, Hirst, J.
登録日2014-06-21
公開日2014-10-01
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.95 Å)
主引用文献Architecture of Mammalian Respiratory Complex I.
Nature, 515, 2014
6G2J
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BU of 6g2j by Molmil
Mouse mitochondrial complex I in the active state
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Agip, A.N.A, Blaza, J.N, Bridges, H.R, Viscomi, C, Rawson, S, Muench, S.P, Hirst, J.
登録日2018-03-23
公開日2018-06-06
最終更新日2021-06-02
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states.
Nat. Struct. Mol. Biol., 25, 2018
6G72
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BU of 6g72 by Molmil
Mouse mitochondrial complex I in the deactive state
分子名称: ACETYL GROUP, ADENOSINE-5'-DIPHOSPHATE, Acyl carrier protein, ...
著者Agip, A.N.A, Blaza, J.N, Bridges, H.R, Viscomi, C, Rawson, S, Muench, S.P, Hirst, J.
登録日2018-04-04
公開日2018-06-06
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states.
Nat. Struct. Mol. Biol., 25, 2018
7B93
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Cryo-EM structure of mitochondrial complex I from Mus musculus inhibited by IACS-2858 at 3.0 A
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-5-[3-[4-(trifluoromethyloxy)phenyl]-1,2,4-oxadiazol-5-yl]pyridin-2-one, ...
著者Chung, I, Hirst, J.
登録日2020-12-14
公開日2021-05-26
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Cork-in-bottle mechanism of inhibitor binding to mammalian complex I.
Sci Adv, 7, 2021
8OLT
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BU of 8olt by Molmil
Mitochondrial complex I from Mus musculus in the active state bound with piericidin A
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
著者Grba, D.N, Chung, I, Bridges, H.R, Agip, A.N.A, Hirst, J.
登録日2023-03-30
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I.
Sci Adv, 9, 2023
8OM1
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BU of 8om1 by Molmil
Mitochondrial complex I from Mus musculus in the active state
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
著者Grba, D.N, Chung, I, Bridges, H.R, Agip, A.N.A, Hirst, J.
登録日2023-03-31
公開日2023-08-09
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I.
Sci Adv, 9, 2023
2V07
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Structure of the Arabidopsis thaliana cytochrome c6A V52Q variant
分子名称: CYTOCHROME C6, HEME C
著者Worrall, J.A.R, Schlarb-Ridley, B.G, Reda, T, Marcaida, M.J, Moorlen, R.J, Wastl, J, Hirst, J, Bendall, D.S, Luisi, B.F, Howe, C.J.
登録日2007-05-09
公開日2007-07-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Modulation of heme redox potential in the cytochrome c6 family.
J. Am. Chem. Soc., 129, 2007
2V08
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Structure of wild-type Phormidium laminosum cytochrome c6
分子名称: CHLORIDE ION, CYTOCHROME C6, HEME C, ...
著者Worrall, J.A.R, Schlarb-Ridley, B.G, Reda, T, Marcaida, M.J, Moorlen, R.J, Wastl, J, Hirst, J, Bendall, D.S, Luisi, B.F, Howe, C.J.
登録日2007-05-10
公開日2007-07-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Modulation of heme redox potential in the cytochrome c6 family.
J. Am. Chem. Soc., 129, 2007
1PC4
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Crystal Structure of the P50A mutant of ferredoxin I at 1.65 A Resolution
分子名称: FE3-S4 CLUSTER, Ferredoxin I, IRON/SULFUR CLUSTER
著者Camba, R, Jung, Y.S, Chen, K, Hunsicker-Wang, L.M, Burgess, B.K, Stout, C.D, Hirst, J, Armstrong, F.A.
登録日2003-05-15
公開日2003-09-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Mechanisms of redox-coupled proton transfer in proteins: role of the proximal proline in reactions of the [3Fe-4S] cluster in Azotobacter vinelandii ferredoxin I
Biochemistry, 42, 2003
1PC5
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Crystal Structure of the P50G Mutant of Ferredoxin I at 1.8 A Resolution
分子名称: FE3-S4 CLUSTER, Ferredoxin I, IRON/SULFUR CLUSTER
著者Camba, R, Jung, Y.S, Chen, K, Hunsicker-Wang, L.M, Burgess, B.K, Stout, C.D, Hirst, J, Armstrong, F.A.
登録日2003-05-15
公開日2003-09-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mechanisms of redox-coupled proton transfer in proteins: role of the proximal proline in reactions of the [3Fe-4S] cluster in Azotobacter vinelandii ferredoxin I
Biochemistry, 42, 2003
1NA8
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BU of 1na8 by Molmil
Crystal structure of ADP-ribosylation factor binding protein GGA1
分子名称: ADP-ribosylation factor binding protein GGA1
著者Lui, W.W, Collins, B.M, Hirst, J, Motley, A, Millar, C, Schu, P, Owen, D.J, Robinson, M.S.
登録日2002-11-27
公開日2003-07-29
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Binding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptin
Mol.Cell.Biol., 14, 2003
1NYK
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BU of 1nyk by Molmil
Crystal Structure of the Rieske protein from Thermus thermophilus
分子名称: FE2/S2 (INORGANIC) CLUSTER, MAGNESIUM ION, Rieske iron-sulfur protein
著者Hunsicker-Wang, L.M, Heine, A, Chen, Y, Luna, E.P, Todaro, T, Zhang, Y.M, Williams, P.A, McRee, D.E, Hirst, J, Stout, C.D, Fee, J.A.
登録日2003-02-12
公開日2003-06-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献High resolution structure of the soluble, respiratory-type Rieske protein from Thermus thermophilus: Analysis and Comparison
Biochemistry, 42, 2003

 

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