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PDB: 34 件

6FPJ
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Structure of the AMPAR GluA3 N-terminal domain bound to phosphate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Herguedas, B, Garcia-Nafria, J, Greger, I.
登録日2018-02-09
公開日2018-12-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Druggability Simulations and X-Ray Crystallography Reveal a Ligand-Binding Site in the GluA3 AMPA Receptor N-Terminal Domain.
Structure, 27, 2019
7QHB
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Active state of GluA1/2 in complex with TARP gamma 8, L-glutamate and CTZ
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, CYCLOTHIAZIDE, ...
著者Herguedas, B, Kohegyi, B, Zhang, D, Greger, I.H.
登録日2021-12-11
公開日2022-02-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanisms underlying TARP modulation of the GluA1/2-gamma 8 AMPA receptor.
Nat Commun, 13, 2022
7QHH
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Desensitized state of GluA1/2 AMPA receptor in complex with TARP-gamma 8 (TMD-LBD)
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, GLUTAMIC ACID, ...
著者Herguedas, B, Kohegyi, B, Dohrke, J.N, Watson, J.F, Zhang, D, Ho, H, Shaikh, S, Lape, R, Krieger, J.M, Greger, I.H.
登録日2021-12-12
公開日2022-02-23
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mechanisms underlying TARP modulation of the GluA1/2-gamma 8 AMPA receptor.
Nat Commun, 13, 2022
6QKC
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GluA1/2 In complex with auxiliary subunit gamma-8
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, Glutamate receptor 1, ...
著者Herguedas, B, Garcia-Nafria, J, Greger, I.G.
登録日2019-01-28
公開日2019-03-27
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP gamma 8.
Science, 364, 2019
3ZUG
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E268D mutant of FAD synthetase from Corynebacterium ammoniagenes
分子名称: RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBF, SULFATE ION
著者Herguedas, B, Martinez-Julvez, M, Serrano, A, Medina, M.
登録日2011-07-19
公開日2012-08-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Key Residues at the Riboflavin Kinase Catalytic Site of the Bifunctional Riboflavin Kinase/Fmn Adenylyltransferase from Corynebacterium Ammoniagenes.
Cell Biochem.Biophys., 65, 2013
2X3U
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Ferredoxin-NADP reductase mutant with Tyr 303 replaced by Phe (Y303F)
分子名称: FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Herguedas, B, Martinez-Julvez, M, Hermoso, J.A, Peregrina, J.R, Sanchez-Azqueta, A, Medina, M.
登録日2010-01-27
公開日2010-05-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Role of Specific Residues in Coenzyme Binding, Charge-Transfer Complex Formation, and Catalysis in Anabaena Ferredoxin Nadp(+)-Reductase.
Biochim.Biophys.Acta, 1797, 2010
6QKZ
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Full length GluA1/2-gamma8 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, ...
著者Herguedas, B, Garcia-Nafria, J, Greger, I.G.
登録日2019-01-30
公開日2019-03-27
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP gamma 8.
Science, 364, 2019
2X0K
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Crystal structure of modular FAD synthetase from Corynebacterium ammoniagenes
分子名称: PYROPHOSPHATE, RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBF, SULFATE ION
著者Herguedas, B, Hermoso, J.A, Martinez-Julvez, M, Medina, M, Frago, S.
登録日2009-12-15
公開日2010-05-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Oligomeric State in the Crystal Structure of Modular Fad Synthetase Provides Insights Into its Sequential Catalysis in Prokaryotes
J.Mol.Biol., 400, 2010
3ESY
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E16KE61K Flavodoxin from Anabaena
分子名称: FLAVIN MONONUCLEOTIDE, Flavodoxin, GLYCEROL
著者Herguedas, B, Martinez-Julvez, M, Hermoso, J.A, Goni, G, Medina, M.
登録日2008-10-06
公開日2009-02-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Flavodoxin: A compromise between efficiency and versatility in the electron transfer from Photosystem I to Ferredoxin-NADP(+) reductase
Biochim.Biophys.Acta, 1787, 2009
3ESX
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E16KE61KD126KD150K Flavodoxin from Anabaena
分子名称: CALCIUM ION, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
著者Herguedas, B, Hermoso, J.A, Martinez-Julvez, M, Goni, G, Medina, M.
登録日2008-10-06
公開日2009-02-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Flavodoxin: A compromise between efficiency and versatility in the electron transfer from Photosystem I to Ferredoxin-NADP(+) reductase
Biochim.Biophys.Acta, 1787, 2009
5A88
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Crystal structure of the riboflavin kinase module of FAD synthetase from Corynebacterium ammoniagenes in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, GLYCEROL, ...
著者Herguedas, B, Martinez-Julvez, M, Hermoso, J.A, Medina, M.
登録日2015-07-13
公開日2015-12-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structural Insights Into the Synthesis of Fmn in Prokaryotic Organisms.
Acta Crystallogr.,Sect.D, 71, 2015
5A8A
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BU of 5a8a by Molmil
Crystal structure of the riboflavin kinase module of FAD synthetase from Corynebacterium ammoniagenes in complex with FMN and ADP (P3 2 21)
分子名称: ADENOSINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Herguedas, B, Martinez-Julvez, M, Hermoso, J.A, Medina, M.
登録日2015-07-13
公開日2015-12-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Insights Into the Synthesis of Fmn in Prokaryotic Organisms.
Acta Crystallogr.,Sect.D, 71, 2015
3ESZ
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K2AK3A Flavodoxin from Anabaena
分子名称: FLAVIN MONONUCLEOTIDE, FLAVODOXIN, GLYCEROL, ...
著者Herguedas, B, Martinez-Julvez, M, Hermoso, J, Goni, G, Medina, M.
登録日2008-10-06
公開日2009-02-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Flavodoxin: A compromise between efficiency and versatility in the electron transfer from Photosystem I to Ferredoxin-NADP(+) reductase
Biochim.Biophys.Acta, 1787, 2009
5A89
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BU of 5a89 by Molmil
Crystal structure of the riboflavin kinase module of FAD synthetase from Corynebacterium ammoniagenes in complex with FMN and ADP(P 21 21 21)
分子名称: ACETIC ACID, ADENOSINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, ...
著者Herguedas, B, Martinez-Julvez, M, Hermoso, J.A, Medina, M.
登録日2015-07-13
公開日2015-12-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Insights Into the Synthesis of Fmn in Prokaryotic Organisms.
Acta Crystallogr.,Sect.D, 71, 2015
4BPR
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BU of 4bpr by Molmil
FERREDOXIN-NADP REDUCTASE MUTANT WITH TYR 79 REPLACED BY PHE (Y79F)
分子名称: FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Herguedas, B, Martinez-Julvez, M, Sanchez-Azqueta, A, Hervas, M, Navarro, J.A, Medina, M.
登録日2013-05-28
公開日2013-11-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Hydrogen Bond Network in the Active Site of Anabaena Ferredoxin-Nadp(+) Reductase Modulates its Catalytic Efficiency.
Biochim.Biophys.Acta, 1837, 2013
2VYQ
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BU of 2vyq by Molmil
FERREDOXIN:NADP REDUCTASE MUTANT WITH THR 155 REPLACED BY GLY, ALA 160 REPLACED BY THR, LEU 263 REPLACED BY PRO AND TYR 303 REPLACED BY SER (T155G-A160T-L263P-Y303S)
分子名称: FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Herguedas, B, Martinez-Julvez, M, Hermoso, J.A, Peregrina, J.R, Medina, M.
登録日2008-07-28
公開日2009-04-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Protein Motifs Involved in Coenzyme Interaction and Enzymatic Efficiency in Anabaena Ferredoxin-Nadp+ Reductase.
Biochemistry, 48, 2009
2VZL
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FERREDOXIN-NADP REDUCTASE (MUTATIONS: T155G, A160T, L263P AND Y303S) COMPLEXED WITH NAD BY COCRYSTALLIZATION
分子名称: FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Herguedas, B, Martinez-Julvez, M, Hermoso, J.A, Peregrina, J.R, Medina, M.
登録日2008-07-28
公開日2009-04-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Protein Motifs Involved in Coenzyme Interaction and Enzymatic Efficiency in Anabaena Ferredoxin-Nadp+ Reductase.
Biochemistry, 48, 2009
2V5V
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W57E Flavodoxin from Anabaena
分子名称: FLAVIN MONONUCLEOTIDE, FLAVODOXIN, MAGNESIUM ION
著者Herguedas, B, Martinez-Julvez, M, Perez-Dorado, I, Goni, G, Medina, M, Hermoso, J.A.
登録日2007-07-10
公開日2007-10-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Tuning of the Fmn Binding and Oxido-Reduction Properties by Neighboring Side Chains in Anabaena Flavodoxin.
Arch.Biochem.Biophys., 467, 2007
5IDE
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BU of 5ide by Molmil
Cryo-EM structure of GluA2/3 AMPA receptor heterotetramer (model I)
分子名称: Glutamate receptor 2, Glutamate receptor 3
著者Herguedas, B, Garcia-Nafria, J, Fernandez-Leiro, R, Greger, I.H.
登録日2016-02-24
公開日2016-03-16
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (8.25 Å)
主引用文献Structure and organization of heteromeric AMPA-type glutamate receptors.
Science, 352, 2016
5IDF
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BU of 5idf by Molmil
Cryo-EM structure of GluA2/3 AMPA receptor heterotetramer (model II)
分子名称: Glutamate receptor 2, Glutamate receptor 3
著者Herguedas, B, Garcia-Nafria, J, Fernandez-Leiro, R, Greger, I.H.
登録日2016-02-24
公開日2016-03-16
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (10.31 Å)
主引用文献Structure and organization of heteromeric AMPA-type glutamate receptors.
Science, 352, 2016
5FWY
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BU of 5fwy by Molmil
Crystal structure of the AMPA receptor GluA2/A3 N-terminal domain heterodimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMATE RECEPTOR 2, GLUTAMATE RECEPTOR 3, ...
著者Herguedas, B, Garcia-Nafria, J, Greger, I.H.
登録日2016-02-21
公開日2016-03-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structure and Organization of Heteromeric Ampa-Type Glutamate Receptors.
Science, 352, 2016
4UZF
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R66E mutant of FAD synthetase from Corynebacterium ammoniagenes
分子名称: PYROPHOSPHATE, RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBF, SULFATE ION
著者Martinez-Julvez, M, Herguedas, B, Milagros, M.
登録日2014-09-05
公開日2015-04-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Quaternary Organization in a Bifunctional Prokaryotic Fad Synthetase: Involvement of an Arginine at its Adenylyltransferase Module on the Riboflavin Kinase Activity.
Biochim.Biophys.Acta, 1854, 2015
4UZE
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R66A mutant of FAD synthetase from Corynebacterium ammoniagenes
分子名称: PYROPHOSPHATE, RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBF, SULFATE ION
著者Martinez-Julvez, M, Herguedas, B, Milagros, M.
登録日2014-09-05
公開日2015-04-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Quaternary Organization in a Bifunctional Prokaryotic Fad Synthetase: Involvement of an Arginine at its Adenylyltransferase Module on the Riboflavin Kinase Activity.
Biochim.Biophys.Acta, 1854, 2015
3ZBT
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BU of 3zbt by Molmil
Ferredoxin-NADP Reductase Mutant with SER 59 Replaced by ALA (S59A)
分子名称: FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Martinez-Julvez, M, Herguedas, B, Sanchez-Azqueta, A, Hervas, M, Navarro, J.A, Medina, M.
登録日2012-11-13
公開日2013-11-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A Hydrogen Bond Network in the Active Site of Anabaena Ferredoxin-Nadp(+) Reductase Modulates its Catalytic Efficiency.
Biochim.Biophys.Acta, 1837, 2013
3ZBU
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Ferredoxin-NADP Reductase Mutant with SER 80 Replaced by ALA (S80A)
分子名称: FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Martinez-Julvez, M, Herguedas, B, Sanchez-Azqueta, A, Hervas, M, Navarro, J.A, Medina, M.
登録日2012-11-13
公開日2013-11-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献A Hydrogen Bond Network in the Active Site of Anabaena Ferredoxin-Nadp(+) Reductase Modulates its Catalytic Efficiency.
Biochim.Biophys.Acta, 1837, 2013

 

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