1CMK
 
 | | CRYSTAL STRUCTURES OF THE MYRISTYLATED CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE REVEAL OPEN AND CLOSED CONFORMATIONS | | 分子名称: | IODIDE ION, MYRISTIC ACID, cAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT, ... | | 著者 | Zheng, J, Knighton, D.R, Xuong, N.-H, Taylor, S.S, Sowadski, J.M, Ten Eyck, L.F. | | 登録日 | 1993-11-18 | | 公開日 | 1994-05-31 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structures of the myristylated catalytic subunit of cAMP-dependent protein kinase reveal open and closed conformations.
Protein Sci., 2, 1993
|
|
2QKC
 | | Structural and Kinetic Study of the Differences between Human and E.coli Manganese Superoxide Dismutases | | 分子名称: | MANGANESE (II) ION, Superoxide dismutase [Mn] | | 著者 | Zheng, J, Domsic, J.F, Cabelli, D, McKenna, R, Silverman, D.N. | | 登録日 | 2007-07-10 | | 公開日 | 2008-07-29 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and kinetic study of differences between human and Escherichia coli manganese superoxide dismutases.
Biochemistry, 46, 2007
|
|
3MJS
 | | Structure of A-type Ketoreductases from Modular Polyketide Synthase | | 分子名称: | (2S)-2-hydroxybutanedioic acid, AmphB, D-MALATE, ... | | 著者 | Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T. | | 登録日 | 2010-04-13 | | 公開日 | 2010-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
|
|
5OQL
 | | Cryo-EM structure of the 90S pre-ribosome from Chaetomium thermophilum | | 分子名称: | 35S rRNA, 40S ribosomal protein S1, 40S ribosomal protein S11-like protein, ... | | 著者 | Cheng, J, Kellner, N, Berninghausen, O, Hurt, E, Beckmann, R. | | 登録日 | 2017-08-12 | | 公開日 | 2017-10-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | 3.2- angstrom -resolution structure of the 90S preribosome before A1 pre-rRNA cleavage.
Nat. Struct. Mol. Biol., 24, 2017
|
|
7OI9
 | | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3B | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2021-05-11 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
|
|
7OIA
 | | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3C | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2021-05-11 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
|
|
5HDI
 | | Structural characterization of CYP144A1, a Mycobacterium tuberculosis cytochrome P450 | | 分子名称: | Cytochrome P450 144, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Chenge, J, Driscoll, M.D, McLean, K.J, Munro, A.W, Leys, D. | | 登録日 | 2016-01-05 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Structural characterization of CYP144A1 - a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis.
Sci Rep, 6, 2016
|
|
7OI7
 | | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 2 | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2021-05-11 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
|
|
7OIE
 | | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 5B | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2021-05-11 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
|
|
7OIC
 | | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 4 | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2021-05-11 | | 公開日 | 2021-09-15 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
|
|
7OIB
 | | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3D | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2021-05-11 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
|
|
7OI8
 | | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3A | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2021-05-11 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
|
|
7OID
 | | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 5A | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2021-05-11 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
|
|
7OI6
 | | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 1 | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2021-05-11 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | | 主引用文献 | A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
|
|
4XXB
 | | Crystal structure of human MDM2-RPL11 | | 分子名称: | 60S ribosomal protein L11, BETA-MERCAPTOETHANOL, E3 ubiquitin-protein ligase Mdm2, ... | | 著者 | Zheng, J, Chen, Z. | | 登録日 | 2015-01-30 | | 公開日 | 2015-08-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activation
Genes Dev., 29, 2015
|
|
4YOC
 | | Crystal Structure of human DNMT1 and USP7/HAUSP complex | | 分子名称: | DNA (cytosine-5)-methyltransferase 1, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION | | 著者 | Cheng, J, Yang, H, Fang, J, Gong, R, Wang, P, Li, Z, Xu, Y. | | 登録日 | 2015-03-11 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.916 Å) | | 主引用文献 | Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation.
Nat Commun, 6, 2015
|
|
8XAR
 | | Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with SAM and Compound 54 | | 分子名称: | 1,2-ETHANEDIOL, 7-chloranyl-2-ethyl-5-pyridin-3-yl-pyrazolo[3,4-c]quinolin-4-one, CHLORIDE ION, ... | | 著者 | Zheng, J.Y, Zhang, G.P, Li, J.J, Tong, S.L. | | 登録日 | 2023-12-05 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | | 主引用文献 | Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with High Selectivity, Brain Penetration, and In Vivo Efficacy.
J.Med.Chem., 67, 2024
|
|
4PT1
 | |
3LC6
 | |
3MJT
 | | Structure of A-type Ketoreductases from Modular Polyketide Synthase | | 分子名称: | AmphB, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T. | | 登録日 | 2010-04-13 | | 公開日 | 2010-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
|
|
3MJC
 | | Structure of A-type Ketoreductases from Modular Polyketide Synthase | | 分子名称: | AmphB, GLYCEROL | | 著者 | Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T. | | 登録日 | 2010-04-12 | | 公開日 | 2010-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
|
|
3MJV
 | | Structure of A-type Ketoreductases from Modular Polyketide Synthase | | 分子名称: | AmphB, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T. | | 登録日 | 2010-04-13 | | 公開日 | 2010-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
|
|
1D68
 | |
3MJE
 | | Structure of A-type Ketoreductases from Modular Polyketide Synthase | | 分子名称: | AmphB, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T. | | 登録日 | 2010-04-12 | | 公開日 | 2010-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
|
|
4P0U
 | |
