1TJ6
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1XOD
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![BU of 1xod by Molmil](/molmil-images/mine/1xod) | Crystal structure of X. tropicalis Spred1 EVH-1 domain | 分子名称: | GLYCEROL, Spred1 | 著者 | Harmer, N.J, Sivak, J.M, Amaya, E, Blundell, T.L. | 登録日 | 2004-10-06 | 公開日 | 2005-01-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | 1.15A Crystal structure of the X. tropicalis Spred1 EVH1 domain suggests a fourth distinct peptide-binding mechanism within the EVH1 family Febs Lett., 579, 2005
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1PWA
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![BU of 1pwa by Molmil](/molmil-images/mine/1pwa) | Crystal structure of Fibroblast Growth Factor 19 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Fibroblast growth factor-19, GLYCEROL, ... | 著者 | Harmer, N.J, Pellegrini, L, Chirgadze, D, Fernandez-Recio, J, Blundell, T.L. | 登録日 | 2003-07-01 | 公開日 | 2004-01-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity. Biochemistry, 43, 2004
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2XBL
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2X3Y
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![BU of 2x3y by Molmil](/molmil-images/mine/2x3y) | Crystal structure of GmhA from Burkholderia pseudomallei | 分子名称: | PHOSPHOHEPTOSE ISOMERASE, ZINC ION | 著者 | Harmer, N.J. | 登録日 | 2010-01-28 | 公開日 | 2010-05-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Structure of Sedoheptulose-7-Phosphate Isomerase from Burkholderia Pseudomallei Reveals a Zinc Binding Site at the Heart of the Active Site. J.Mol.Biol., 400, 2010
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2Q1T
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![BU of 2q1t by Molmil](/molmil-images/mine/2q1t) | Crystal structure of the Bordetella bronchiseptica enzyme WbmF in complex with NAD+ and UDP | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative nucleotide sugar epimerase/ dehydratase, URIDINE-5'-DIPHOSPHATE | 著者 | Harmer, N.J, King, J.D, Palmer, C.M, Maskell, D, Blundell, T.L. | 登録日 | 2007-05-25 | 公開日 | 2007-10-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Predicting protein function from structure--the roles of short-chain dehydrogenase/reductase enzymes in Bordetella O-antigen biosynthesis. J.Mol.Biol., 374, 2007
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2PZM
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![BU of 2pzm by Molmil](/molmil-images/mine/2pzm) | Crystal structure of the Bordetella bronchiseptica enzyme WbmG in complex with NAD and UDP | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative nucleotide sugar epimerase/ dehydratase, SULFATE ION, ... | 著者 | Harmer, N.J, King, J.D, Palmer, C.M, Maskell, D, Blundell, T.L. | 登録日 | 2007-05-18 | 公開日 | 2007-10-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Predicting protein function from structure--the roles of short-chain dehydrogenase/reductase enzymes in Bordetella O-antigen biosynthesis. J.Mol.Biol., 374, 2007
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2Q1U
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![BU of 2q1u by Molmil](/molmil-images/mine/2q1u) | Crystal structure of the Bordetella bronchiseptica enzyme WbmF in complex with NAD+ and UDP | 分子名称: | GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative nucleotide sugar epimerase/ dehydratase, ... | 著者 | Harmer, N.J, King, J.D, Palmer, C.M, Maskell, D, Blundell, T.L. | 登録日 | 2007-05-25 | 公開日 | 2007-10-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Predicting protein function from structure--the roles of short-chain dehydrogenase/reductase enzymes in Bordetella O-antigen biosynthesis. J.Mol.Biol., 374, 2007
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2Q1S
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![BU of 2q1s by Molmil](/molmil-images/mine/2q1s) | Crystal structure of the Bordetella bronchiseptica enzyme WbmF in complex with NADH | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Putative nucleotide sugar epimerase/ dehydratase | 著者 | Harmer, N.J, King, J.D, Palmer, C.M, Maskell, D, Blundell, T.L. | 登録日 | 2007-05-25 | 公開日 | 2007-10-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Predicting protein function from structure--the roles of short-chain dehydrogenase/reductase enzymes in Bordetella O-antigen biosynthesis. J.Mol.Biol., 374, 2007
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2PZJ
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![BU of 2pzj by Molmil](/molmil-images/mine/2pzj) | Crystal structure of the Bordetella bronchiseptica enzyme WbmF in complex with NAD+ | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative nucleotide sugar epimerase/ dehydratase | 著者 | Harmer, N.J, King, J.D, Palmer, C.M, Maskell, D, Blundell, T.L. | 登録日 | 2007-05-18 | 公開日 | 2007-10-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Predicting protein function from structure--the roles of short-chain dehydrogenase/reductase enzymes in Bordetella O-antigen biosynthesis. J.Mol.Biol., 374, 2007
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4USK
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![BU of 4usk by Molmil](/molmil-images/mine/4usk) | Unravelling the B. pseudomallei heptokinase WcbL: from Structure to Drug Discovery. | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, PUTATIVE SUGAR KINASE, ... | 著者 | Vivoli, M, Isupov, M.N, Nicholas, R, Hill, A, Scott, A, Kosma, P, Prior, J, Harmer, N.J. | 登録日 | 2014-07-09 | 公開日 | 2016-01-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Unraveling the B.Pseudomallei Heptokinase Wcbl: From Structure to Drug Discovery. Chem.Biol., 22, 2015
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4USM
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![BU of 4usm by Molmil](/molmil-images/mine/4usm) | WcbL complex with glycerol bound to sugar site | 分子名称: | CHLORIDE ION, GLYCEROL, PUTATIVE SUGAR KINASE | 著者 | Vivoli, M, Isupov, M.N, Nicholas, R, Hill, A, Scott, A, Kosma, P, Prior, J, Harmer, N.J. | 登録日 | 2014-07-10 | 公開日 | 2016-01-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Unraveling the B.Pseudomallei Heptokinase Wcbl: From Structure to Drug Discovery. Chem.Biol., 22, 2015
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4UT4
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![BU of 4ut4 by Molmil](/molmil-images/mine/4ut4) | Burkholderia pseudomallei heptokinase WcbL, D-mannose complex. | 分子名称: | CHLORIDE ION, PUTATIVE SUGAR KINASE, alpha-D-mannopyranose | 著者 | Vivoli, M, Isupov, M.N, Nicholas, R, Hill, A, Scott, A, Kosma, P, Prior, J, Harmer, N.J. | 登録日 | 2014-07-18 | 公開日 | 2016-01-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Unraveling the B.Pseudomallei Heptokinase Wcbl: From Structure to Drug Discovery. Chem.Biol., 22, 2015
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5FRD
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![BU of 5frd by Molmil](/molmil-images/mine/5frd) | Structure of a thermophilic esterase | 分子名称: | CARBOXYLESTERASE (EST-2), CHLORIDE ION, CITRATE ANION, ... | 著者 | Sayer, C, Finnigan, W, Isupov, M.N, Levisson, M, Kengen, S.W.M, van der Oost, J, Harmer, N, Littlechild, J.A. | 登録日 | 2015-12-17 | 公開日 | 2016-05-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural and Biochemical Characterisation of Archaeoglobus Fulgidus Esterase Reveals a Bound Coa Molecule in the Vicinity of the Active Site. Sci.Rep., 6, 2016
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4UTG
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![BU of 4utg by Molmil](/molmil-images/mine/4utg) | Burkholderia pseudomallei heptokinase WcbL,AMPPNP (ATP analogue) complex. | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Vivoli, M, Isupov, M.N, Nicholas, R, Hill, A, Scott, A, Kosma, P, Prior, J, Harmer, N.J. | 登録日 | 2014-07-21 | 公開日 | 2016-01-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Unraveling the B.Pseudomallei Heptokinase Wcbl: From Structure to Drug Discovery. Chem.Biol., 22, 2015
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7PQ9
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![BU of 7pq9 by Molmil](/molmil-images/mine/7pq9) | Crystal structure of Bacillus clausii pdxR at 2.8 Angstroms resolution | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Vivoli Vega, M, Isupov, M.N, Harmer, N. | 登録日 | 2021-09-16 | 公開日 | 2022-09-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR. Nucleic Acids Res., 51, 2023
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7PVI
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![BU of 7pvi by Molmil](/molmil-images/mine/7pvi) | dTDP-sugar epimerase | 分子名称: | CITRATE ANION, SODIUM ION, alpha-D-xylopyranose, ... | 著者 | Cross, A.R, Harmer, N.J, Isupov, M.N. | 登録日 | 2021-10-04 | 公開日 | 2022-04-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.434 Å) | 主引用文献 | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases. J.Biol.Chem., 298, 2022
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7PWB
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![BU of 7pwb by Molmil](/molmil-images/mine/7pwb) | dTDP-sugar epimerase from Coxiella burnetii in complex with dTDP | 分子名称: | 1,2-ETHANEDIOL, CITRIC ACID, THYMIDINE-5'-DIPHOSPHATE, ... | 著者 | Cross, A.R, Harmer, N.J, Isupov, M.N. | 登録日 | 2021-10-06 | 公開日 | 2022-04-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases. J.Biol.Chem., 298, 2022
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7PWH
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![BU of 7pwh by Molmil](/molmil-images/mine/7pwh) | Structure of the dTDP-sugar epimerase StrM | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, THYMIDINE-5'-DIPHOSPHATE, ... | 著者 | Cross, A.R, Harmer, N.J, Isupov, M.N. | 登録日 | 2021-10-06 | 公開日 | 2022-04-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases. J.Biol.Chem., 298, 2022
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7PWI
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![BU of 7pwi by Molmil](/molmil-images/mine/7pwi) | Structure of the dTDP-sugar epimerase StrM | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, dTDP-4-keto-rhamnose 3,5-epimerase,dTDP-4-dehydrorhamnose 3,5-epimerase | 著者 | Cross, A.R, Harmer, N.J, Isupov, M.N. | 登録日 | 2021-10-06 | 公開日 | 2022-04-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.326 Å) | 主引用文献 | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases. J.Biol.Chem., 298, 2022
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2Y78
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![BU of 2y78 by Molmil](/molmil-images/mine/2y78) | Crystal structure of BPSS1823, a Mip-like chaperone from Burkholderia pseudomallei | 分子名称: | CHLORIDE ION, GLYCEROL, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE, ... | 著者 | Norville, I.H, O'Shea, K, Sarkar-Tyson, M, Harmer, N.J. | 登録日 | 2011-01-28 | 公開日 | 2011-05-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (0.91 Å) | 主引用文献 | The Structure of a Burkholderia Pseudomallei Immunophilin-Inhibitor Complex Reveals New Approaches to Antimicrobial Development Biochem.J., 437, 2011
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4BQO
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![BU of 4bqo by Molmil](/molmil-images/mine/4bqo) | Structural insights into WcbI, a novel polysaccharide biosynthesis enzyme. Native protein without disulfide bond between COA and Cys14. | 分子名称: | BROMIDE ION, COENZYME A, DI(HYDROXYETHYL)ETHER, ... | 著者 | Vivoli, M, Ayres, E, Isupov, M.N, Harmer, N.J. | 登録日 | 2013-05-31 | 公開日 | 2013-11-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Structural Insights Into Wcbi, a Novel Polysaccharide-Biosynthesis Enzyme. Iucrj, 1, 2014
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4BQN
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![BU of 4bqn by Molmil](/molmil-images/mine/4bqn) | Structural insights into WcbI, a novel polysaccharide biosynthesis enzyme. Native protein. | 分子名称: | CAPSULAR POLYSACCHARIDE BIOSYNTHESIS PROTEIN, CHLORIDE ION, COENZYME A, ... | 著者 | Vivoli, M, Ayres, E, Isupov, M.N, Harmer, N.J. | 登録日 | 2013-05-31 | 公開日 | 2013-11-06 | 最終更新日 | 2014-08-13 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Structural Insights Into Wcbi, a Novel Polysaccharide-Biosynthesis Enzyme. Iucrj, 1, 2014
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4C26
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![BU of 4c26 by Molmil](/molmil-images/mine/4c26) | Solution NMR structure of the HicA toxin from Burkholderia pseudomallei | 分子名称: | HICA | 著者 | Butt, A, Higman, V.A, Williams, C, Crump, M.P, Hemsley, C, Harmer, N, Titball, R.W. | 登録日 | 2013-08-16 | 公開日 | 2014-04-23 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The Hica Toxin from Burkholderia Pseudomallei Has a Role in Persister Cell Formation. Biochem.J., 459, 2014
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6HNK
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![BU of 6hnk by Molmil](/molmil-images/mine/6hnk) | The ligand-free, open structure of CD0873, a substrate binding protein with adhesive properties from Clostridium difficile. | 分子名称: | ABC-type transport system, sugar-family extracellular solute-binding protein | 著者 | Bradshaw, W.J, Kovacs-Simon, A, Harmer, N.J, Michell, S.L, Acharya, K.R. | 登録日 | 2018-09-15 | 公開日 | 2019-08-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular features of lipoprotein CD0873: A potential vaccine against the human pathogenClostridioides difficile. J.Biol.Chem., 294, 2019
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