3CO9
 
 | | Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor | | 分子名称: | N-{3-[4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydropyrrolo[1,2-b]pyridazin-3-yl]-1,1-dioxido-2H-1,2,4-benzothiadiazin-7 -yl}methanesulfonamide, RNA-directed RNA polymerase | | 著者 | Han, Q, Showalter, R.E, Zhao, Q, Kissinger, C.R. | | 登録日 | 2008-03-27 | | 公開日 | 2009-02-10 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Pyrrolo[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase.
Bioorg.Med.Chem.Lett., 18, 2008
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3DHE
 | | ESTROGENIC 17-BETA HYDROXYSTEROID DEHYDROGENASE COMPLEXED DEHYDROEPIANDROSTERONE | | 分子名称: | 3-BETA-HYDROXY-5-ANDROSTEN-17-ONE, ESTROGENIC 17-BETA HYDROXYSTEROID DEHYDROGENASE | | 著者 | Han, Q, Campbell, R.L, Gangloff, A, Lin, S.X. | | 登録日 | 1998-03-25 | | 公開日 | 1999-09-25 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Dehydroepiandrosterone and dihydrotestosterone recognition by human estrogenic 17beta-hydroxysteroid dehydrogenase. C-18/c-19 steroid discrimination and enzyme-induced strain.
J.Biol.Chem., 275, 2000
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2R5E
 | | Aedes kynurenine aminotransferase in complex with glutamine | | 分子名称: | Kynurenine aminotransferase, N~2~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-GLUTAMINE | | 著者 | Han, Q, Gao, Y.G, Robinson, H, Li, J. | | 登録日 | 2007-09-03 | | 公開日 | 2008-03-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Structural insight into the mechanism of substrate specificity of aedes kynurenine aminotransferase.
Biochemistry, 47, 2008
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8UKD
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8UIR
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8V0M
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9AYX
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9AYY
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8V0L
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8V0U
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8W5A
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8W59
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