7AFV
 
 | | Crystal structure of tetrameric beta-2-microglobulin deltaN6 S52C stabilized by a covalent ligand | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-oxidanylidene-~{N}-(2-sulfanylethyl)-2,3-dihydro-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide, Beta-2-microglobulin | | Authors: | Guthertz, N, Cawood, E, Karamanos, T. | | Deposit date: | 2020-09-20 | | Release date: | 2020-12-09 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Modulation of Amyloidogenic Protein Self-Assembly Using Tethered Small Molecules.
J.Am.Chem.Soc., 142, 2020
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7NMO
 | | Crystal structure of beta-2-microglobulin D76A mutant | | Descriptor: | Beta-2-microglobulin | | Authors: | Guthertz, N. | | Deposit date: | 2021-02-23 | | Release date: | 2022-08-03 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7NMR
 | | Crystal structure of beta-2-microglobulin D76S mutant | | Descriptor: | Beta-2-microglobulin, GLYCEROL | | Authors: | Guthertz, N. | | Deposit date: | 2021-02-23 | | Release date: | 2022-08-03 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7NMT
 | | Crystal structure of beta-2-microglobulin D76G mutant | | Descriptor: | Beta-2-microglobulin | | Authors: | Guthertz, N. | | Deposit date: | 2021-02-23 | | Release date: | 2022-08-03 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7NMC
 | | Crystal structure of beta-2-microglobulin D76E mutant | | Descriptor: | Beta-2-microglobulin, GLYCEROL, TRIETHYLENE GLYCOL | | Authors: | Guthertz, N. | | Deposit date: | 2021-02-23 | | Release date: | 2022-08-03 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7NMV
 | | Crystal structure of beta-2-microglobulin D76Q mutant | | Descriptor: | Beta-2-microglobulin | | Authors: | Guthertz, N. | | Deposit date: | 2021-02-23 | | Release date: | 2022-08-03 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7NMY
 | | Crystal structure of beta-2-microglobulin D76Y mutant | | Descriptor: | Beta-2-microglobulin | | Authors: | Guthertz, N. | | Deposit date: | 2021-02-23 | | Release date: | 2022-08-03 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7NN5
 | | Crystal structure of beta-2-microglobulin D76K mutant | | Descriptor: | Beta-2-microglobulin | | Authors: | Guthertz, N. | | Deposit date: | 2021-02-24 | | Release date: | 2022-08-03 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.242 Å) | | Cite: | The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
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5N9G
 | | TFIIIB -TBP/Brf2/DNA and SANT domain of Bdp1- | | Descriptor: | DNA/RNA (25-MER), DNA/RNA (27-MER), SODIUM ION, ... | | Authors: | Gouge, J, Vannini, A, Guthertz, N. | | Deposit date: | 2017-02-24 | | Release date: | 2017-06-14 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation.
Nat Commun, 8, 2017
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4ROE
 | | Human TFIIB-related factor 2 (Brf2) and TBP bound to RPPH1 promoter | | Descriptor: | MAGNESIUM ION, Non-template strand, TATA-box-binding protein, ... | | Authors: | Vannini, A, Gouge, J, Satia, K, Guthertz, N. | | Deposit date: | 2014-10-28 | | Release date: | 2015-12-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2.
Cell(Cambridge,Mass.), 163, 2015
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4ROD
 | | Human TFIIB-related factor 2 (Brf2) and TBP bound to TRNAU1 promoter | | Descriptor: | Non-template strand, TATA-box-binding protein, Template strand, ... | | Authors: | Vannini, A, Gouge, J, Satia, K, Guthertz, N. | | Deposit date: | 2014-10-28 | | Release date: | 2015-12-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2.
Cell(Cambridge,Mass.), 163, 2015
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4ROC
 | | Human TFIIB-related factor 2 (Brf2) and TBP bound to U6#2 promoter | | Descriptor: | MAGNESIUM ION, Non-template strand, TATA-box-binding protein, ... | | Authors: | Vannini, A, Gouge, J, Satia, K, Guthertz, N. | | Deposit date: | 2014-10-28 | | Release date: | 2015-12-30 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2.
Cell(Cambridge,Mass.), 163, 2015
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