2V8N
 
 | | Wild-type Structure of Lactose Permease | | 分子名称: | LACTOSE PERMEASE | | 著者 | Guan, L, Mirza, O, Verner, G, Iwata, S, Kaback, H.R. | | 登録日 | 2007-08-09 | | 公開日 | 2007-09-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural Determination of Wild-Type Lactose Permease.
Proc.Natl.Acad.Sci.USA, 104, 2007
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7L17
 | | Crystal structure of sugar-bound melibiose permease MelB | | 分子名称: | 4-nitrophenyl alpha-D-galactopyranoside, Melibiose carrier protein | | 著者 | Guan, L. | | 登録日 | 2020-12-14 | | 公開日 | 2021-08-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | X-ray crystallography reveals molecular recognition mechanism for sugar binding in a melibiose transporter MelB.
Commun Biol, 4, 2021
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7L16
 | | Crystal structure of sugar-bound melibiose permease MelB | | 分子名称: | Melibiose carrier protein, dodecyl 6-O-alpha-D-galactopyranosyl-beta-D-glucopyranoside | | 著者 | Guan, L. | | 登録日 | 2020-12-14 | | 公開日 | 2021-08-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | X-ray crystallography reveals molecular recognition mechanism for sugar binding in a melibiose transporter MelB.
Commun Biol, 4, 2021
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8T60
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8FQ9
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8FRH
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6PA0
 | | Structure of the G77A mutant in Sodium Chloride | | 分子名称: | Antibody HEAVY fragment, Antibody LIGHT fragment, DIACYL GLYCEROL, ... | | 著者 | Cuello, L.G, Guan, L. | | 登録日 | 2019-06-11 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure, function, and ion-binding properties of a K+channel stabilized in the 2,4-ion-bound configuration.
Proc.Natl.Acad.Sci.USA, 116, 2019
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2Y5Y
 | | Crystal structure of LacY in complex with an affinity inactivator | | 分子名称: | 2-sulfanylethyl beta-D-galactopyranoside, BARIUM ION, LACTOSE PERMEASE | | 著者 | Chaptal, V, Kwon, S, Sawaya, M.R, Guan, L, Kaback, H.R, Abramson, J. | | 登録日 | 2011-01-19 | | 公開日 | 2011-06-15 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | | 主引用文献 | Crystal Structure of Lactose Permease in Complex with an Affinity Inactivator Yields Unique Insight Into Sugar Recognition.
Proc.Natl.Acad.Sci.USA, 108, 2011
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6NFV
 | | Structure of the KcsA-G77C mutant or the 2,4-ion bound configuration of a K+ channel selectivity filter. | | 分子名称: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, NONAN-1-OL, POTASSIUM ION, ... | | 著者 | Tilegenova, C, Cortes, D.M, Jahovic, N, Hardy, E, Parameswaran, H, Guan, L, Cuello, L.G. | | 登録日 | 2018-12-20 | | 公開日 | 2019-08-07 | | 最終更新日 | 2019-12-18 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Structure, function, and ion-binding properties of a K+channel stabilized in the 2,4-ion-bound configuration.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6NFU
 | | Structure of the KcsA-G77A mutant or the 2,4-ion bound configuration of a K+ channel selectivity filter. | | 分子名称: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, NONAN-1-OL, POTASSIUM ION, ... | | 著者 | Tilegenova, C, Cortes, D.M, Jahovic, N, Hardy, E, Parameswaran, H, Guan, L, Cuello, L.G. | | 登録日 | 2018-12-20 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structure, function, and ion-binding properties of a K+channel stabilized in the 2,4-ion-bound configuration.
Proc.Natl.Acad.Sci.USA, 116, 2019
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2CFP
 | | Sugar Free Lactose Permease at acidic pH | | 分子名称: | LACTOSE PERMEASE, MERCURY (II) ION | | 著者 | Mirza, O, Guan, L, Verner, G, Iwata, S, Kaback, H.R. | | 登録日 | 2006-02-22 | | 公開日 | 2006-03-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural Evidence for Induced Fit and a Mechanism for Sugar/H(+) Symport in Lacy.
Embo J., 25, 2006
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2CFQ
 | | Sugar Free Lactose Permease at neutral pH | | 分子名称: | LACTOSE PERMEASE, MERCURY (II) ION | | 著者 | Mirza, O, Guan, L, Verner, G, Iwata, S, Kaback, H.R. | | 登録日 | 2006-02-22 | | 公開日 | 2006-03-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural Evidence for Induced Fit and a Mechanism for Sugar/H(+) Symport in Lacy.
Embo J., 25, 2006
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4M64
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4O60
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4QFV
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9CUO
 | | Crystal structure of CRBN with compound 3 | | 分子名称: | (3S)-3-(3-methyl-2-oxo-2,3-dihydro-1H-1,3-benzimidazol-1-yl)piperidine-2,6-dione, 1,2-ETHANEDIOL, Protein cereblon, ... | | 著者 | Zheng, X, Ji, N, Campbell, V, Slavin, A, Zhu, X, Chen, D, Rong, H, Enerson, B, Mayo, M, Sharma, K, Browne, C.M, Klaus, C.R, Li, H, Massa, G, McDonald, A.A, Shi, Y, Sintchak, M, Skouras, S, Walther, D.M, Yuan, K, Zhang, Y, Kelleher, J, Guang, L, Luo, X, Mainolfi, N, Weiss, M.M. | | 登録日 | 2024-07-26 | | 公開日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Discovery of KT-474─a Potent, Selective, and Orally Bioavailable IRAK4 Degrader for the Treatment of Autoimmune Diseases.
J.Med.Chem., 2024
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5XHQ
 | | Apolipoprotein N-acyl Transferase | | 分子名称: | Apolipoprotein N-acyltransferase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Yingzhi, X, Yong, X, Guangyuan, L, Fei, S. | | 登録日 | 2017-04-23 | | 公開日 | 2017-07-26 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.587 Å) | | 主引用文献 | Crystal structure of E. coli apolipoprotein N-acyl transferase
Nat Commun, 8, 2017
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