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PDB: 23 件
2V8N
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Wild-type Structure of Lactose Permease
分子名称: LACTOSE PERMEASE
著者Guan, L, Mirza, O, Verner, G, Iwata, S, Kaback, H.R.
登録日2007-08-09
公開日2007-09-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural Determination of Wild-Type Lactose Permease.
Proc.Natl.Acad.Sci.USA, 104, 2007
3WI7
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BU of 3wi7 by Molmil
Crystal Structure of the Novel Haloalkane Dehalogenase DatA from Agrobacterium tumefaciens C58
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Haloalkane dehalogenase
著者Guan, L.J, Yabuki, H, Okai, M, Ohtsuka, J, Tanokura, M.
登録日2013-09-06
公開日2014-07-23
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the novel haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58 reveals a special halide-stabilizing pair and enantioselectivity mechanism.
Appl.Microbiol.Biotechnol., 98, 2014
3WIB
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Crystal structure of Y109W Mutant Haloalkane Dehalogenase DatA from Agrobacterium tumefaciens C58
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Haloalkane dehalogenase
著者Guan, L.J, Yabuki, H, Okai, M, Ohtsuka, J, Tanokura, M.
登録日2013-09-09
公開日2014-07-23
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the novel haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58 reveals a special halide-stabilizing pair and enantioselectivity mechanism.
Appl.Microbiol.Biotechnol., 98, 2014
3WWI
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Crystal structure of the G136F mutant of the first R-stereoselective -transaminase identified from Arthrobacter sp. KNK168 (FERM-BP-5228)
分子名称: (R)-amine transaminase, PYRIDOXAL-5'-PHOSPHATE
著者Guan, L.J, Ohtsuka, J, Miyakawa, T, Zhi, Y, Ito, N, Yasohara, Y, Tanokura, M.
登録日2014-06-18
公開日2015-08-19
最終更新日2020-01-22
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献A new target region for changing the substrate specificity of amine transaminases.
Sci Rep, 5, 2015
3WWJ
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Crystal structure of an engineered sitagliptin-producing transaminase, ATA-117-Rd11
分子名称: (R)-amine transaminase, PYRIDOXAL-5'-PHOSPHATE
著者Guan, L.J, Ohtsuka, J, Okai, M, Miyakawa, T, Mase, T, Zhi, Y, Hou, F, Ito, N, Yasohara, Y, Tanokura, M.
登録日2014-06-18
公開日2015-08-12
最終更新日2018-11-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A new target region for changing the substrate specificity of amine transaminases.
Sci Rep, 5, 2015
3X0Y
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Crystal structure of FMN-bound DszC from Rhodococcus erythropolis D-1
分子名称: DszC, FLAVIN MONONUCLEOTIDE
著者Guan, L.J, Lee, W.C, Wang, S.P, Ohtsuka, J, Tanokura, M.
登録日2014-10-23
公開日2015-02-25
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of apo-DszC and FMN-bound DszC from Rhodococcus erythropolis D-1.
Febs J., 282, 2015
3X0X
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Crystal structure of apo-DszC from Rhodococcus erythropolis D-1
分子名称: DszC
著者Guan, L.J, Lee, W.C, Wang, S.P, Ohtsuka, J, Tanokura, M.
登録日2014-10-23
公開日2015-02-25
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Crystal structures of apo-DszC and FMN-bound DszC from Rhodococcus erythropolis D-1.
Febs J., 282, 2015
3WWH
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Crystal structure of the first R-stereoselective -transaminase identified from Arthrobacter sp. KNK168 (FERM-BP-5228)
分子名称: (R)-amine transaminase, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE
著者Guan, L.J, Ohtsuka, J, Okai, M, Miyakawa, T, Mase, T, Zhi, Y, Ito, N, Yasohara, Y, Tanokura, M.
登録日2014-06-18
公開日2015-08-12
最終更新日2018-11-21
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A new target region for changing the substrate specificity of amine transaminases.
Sci Rep, 5, 2015
8T60
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CryoEM structure of an inward-facing MelBSt at a Na(+)-bound and sugar low-affinity conformation
分子名称: Melibiose permease, NabFab_H Chain, NabFab_L Chain, ...
著者Guan, L.
登録日2023-06-14
公開日2024-02-28
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Mobile barrier mechanisms for Na + -coupled symport in an MFS sugar transporter.
Elife, 12, 2024
8FQ9
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Crystal structure of a ligand-bound cation-site mutant D55C of a melibiose transporter
分子名称: Melibiose permease, PENTAETHYLENE GLYCOL, dodecyl 6-O-alpha-D-galactopyranosyl-beta-D-glucopyranoside
著者Guan, L.
登録日2023-01-05
公開日2024-06-05
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of a ligand-bound cation-site mutant D55C of a melibiose transporter
To Be Published
8FRH
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Apo structure of D59C mutant of a melibiose transporter
分子名称: Melibiose permease, PENTAETHYLENE GLYCOL
著者Guan, L, Hariharan, P.
登録日2023-01-06
公開日2024-06-05
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Apo structure of D59C mutant of a melibiose transporter
To Be Published
7L16
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Crystal structure of sugar-bound melibiose permease MelB
分子名称: Melibiose carrier protein, dodecyl 6-O-alpha-D-galactopyranosyl-beta-D-glucopyranoside
著者Guan, L.
登録日2020-12-14
公開日2021-08-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献X-ray crystallography reveals molecular recognition mechanism for sugar binding in a melibiose transporter MelB.
Commun Biol, 4, 2021
7L17
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Crystal structure of sugar-bound melibiose permease MelB
分子名称: 4-nitrophenyl alpha-D-galactopyranoside, Melibiose carrier protein
著者Guan, L.
登録日2020-12-14
公開日2021-08-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献X-ray crystallography reveals molecular recognition mechanism for sugar binding in a melibiose transporter MelB.
Commun Biol, 4, 2021
2Y5Y
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Crystal structure of LacY in complex with an affinity inactivator
分子名称: 2-sulfanylethyl beta-D-galactopyranoside, BARIUM ION, LACTOSE PERMEASE
著者Chaptal, V, Kwon, S, Sawaya, M.R, Guan, L, Kaback, H.R, Abramson, J.
登録日2011-01-19
公開日2011-06-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.38 Å)
主引用文献Crystal Structure of Lactose Permease in Complex with an Affinity Inactivator Yields Unique Insight Into Sugar Recognition.
Proc.Natl.Acad.Sci.USA, 108, 2011
6PA0
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BU of 6pa0 by Molmil
Structure of the G77A mutant in Sodium Chloride
分子名称: Antibody HEAVY fragment, Antibody LIGHT fragment, DIACYL GLYCEROL, ...
著者Cuello, L.G, Guan, L.
登録日2019-06-11
公開日2019-08-07
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure, function, and ion-binding properties of a K+channel stabilized in the 2,4-ion-bound configuration.
Proc.Natl.Acad.Sci.USA, 116, 2019
6NFV
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Structure of the KcsA-G77C mutant or the 2,4-ion bound configuration of a K+ channel selectivity filter.
分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, NONAN-1-OL, POTASSIUM ION, ...
著者Tilegenova, C, Cortes, D.M, Jahovic, N, Hardy, E, Parameswaran, H, Guan, L, Cuello, L.G.
登録日2018-12-20
公開日2019-08-07
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structure, function, and ion-binding properties of a K+channel stabilized in the 2,4-ion-bound configuration.
Proc.Natl.Acad.Sci.USA, 116, 2019
6NFU
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BU of 6nfu by Molmil
Structure of the KcsA-G77A mutant or the 2,4-ion bound configuration of a K+ channel selectivity filter.
分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, NONAN-1-OL, POTASSIUM ION, ...
著者Tilegenova, C, Cortes, D.M, Jahovic, N, Hardy, E, Parameswaran, H, Guan, L, Cuello, L.G.
登録日2018-12-20
公開日2019-08-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structure, function, and ion-binding properties of a K+channel stabilized in the 2,4-ion-bound configuration.
Proc.Natl.Acad.Sci.USA, 116, 2019
2CFQ
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BU of 2cfq by Molmil
Sugar Free Lactose Permease at neutral pH
分子名称: LACTOSE PERMEASE, MERCURY (II) ION
著者Mirza, O, Guan, L, Verner, G, Iwata, S, Kaback, H.R.
登録日2006-02-22
公開日2006-03-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural Evidence for Induced Fit and a Mechanism for Sugar/H(+) Symport in Lacy.
Embo J., 25, 2006
2CFP
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BU of 2cfp by Molmil
Sugar Free Lactose Permease at acidic pH
分子名称: LACTOSE PERMEASE, MERCURY (II) ION
著者Mirza, O, Guan, L, Verner, G, Iwata, S, Kaback, H.R.
登録日2006-02-22
公開日2006-03-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural Evidence for Induced Fit and a Mechanism for Sugar/H(+) Symport in Lacy.
Embo J., 25, 2006
4O60
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Structure of ankyrin repeat protein
分子名称: ANK-N5C-317
著者Ethayathulla, A.S, Guan, L.
登録日2013-12-20
公開日2015-03-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献A transcription blocker isolated from a designed repeat protein combinatorial library by in vivo functional screen.
Sci Rep, 5, 2015
4M64
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3D crystal structure of Na+/melibiose symporter of Salmonella typhimurium
分子名称: Melibiose carrier protein
著者Ethayathulla, A.S, Guan, L.
登録日2013-08-08
公開日2014-01-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Structure-based mechanism for Na(+)/melibiose symport by MelB.
Nat Commun, 5, 2014
4QFV
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Crystal structure of a unique ankyrin
分子名称: ACETATE ION, ANK-N5C-281
著者Ethayathulla, A.S, Tikhonova, E.B, Guan, L.
登録日2014-05-21
公開日2015-05-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献A transcription blocker isolated from a designed repeat protein combinatorial library by in vivo functional screen.
Sci Rep, 5, 2015
5XHQ
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Apolipoprotein N-acyl Transferase
分子名称: Apolipoprotein N-acyltransferase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Yingzhi, X, Yong, X, Guangyuan, L, Fei, S.
登録日2017-04-23
公開日2017-07-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.587 Å)
主引用文献Crystal structure of E. coli apolipoprotein N-acyl transferase
Nat Commun, 8, 2017

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