7NUK
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![BU of 7nuk by Molmil](/molmil-images/mine/7nuk) | Crystal structure of SARS CoV2 main protease in complex with EG009 (modelled using PanDDA event map) | Descriptor: | 2-[2-chloranylethanoyl(propyl)amino]-~{N}-(2-methoxyphenyl)ethanamide, 3C-like proteinase, DIMETHYL SULFOXIDE | Authors: | Oerlemans, R, Eris, D, Wang, M, Sharpe, M, Domling, A, Groves, M.R. | Deposit date: | 2021-03-12 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Combining High-Throughput Synthesis and High-Throughput Protein Crystallography for Accelerated Hit Identification. Angew.Chem.Int.Ed.Engl., 60, 2021
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6RRR
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![BU of 6rrr by Molmil](/molmil-images/mine/6rrr) | Crystal structure of the tyrosinase PvdP from Pseudomonas aeruginosa | Descriptor: | GLYCEROL, PvdP | Authors: | Wibowo, J.P, Batista, F.A, van Oosterwijk, N, Groves, M.R, Dekker, F.J, Quax, W.J. | Deposit date: | 2019-05-20 | Release date: | 2020-04-15 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | A novel mechanism of inhibition by phenylthiourea on PvdP, a tyrosinase synthesizing pyoverdine of Pseudomonas aeruginosa. Int.J.Biol.Macromol., 146, 2020
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6RRQ
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![BU of 6rrq by Molmil](/molmil-images/mine/6rrq) | Crystal structure of tyrosinase PvdP from Pseudomonas aeruginosa bound to copper | Descriptor: | COPPER (II) ION, GLYCEROL, PvdP | Authors: | Wibowo, J.P, Batista, F.A, van Oosterwijk, N, Groves, M.R, Dekker, F.J, Quax, W.J. | Deposit date: | 2019-05-20 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A novel mechanism of inhibition by phenylthiourea on PvdP, a tyrosinase synthesizing pyoverdine of Pseudomonas aeruginosa. Int.J.Biol.Macromol., 146, 2020
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6RRP
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![BU of 6rrp by Molmil](/molmil-images/mine/6rrp) | Crystal structure of tyrosinase PvdP from Pseudomonas aeruginosa bound to copper and phenylthiourea | Descriptor: | COPPER (II) ION, N-PHENYLTHIOUREA, PvdP | Authors: | Wibowo, J.P, Batista, F.A, van Oosterwijk, N, Groves, M.R, Dekker, F.J, Quax, W.J. | Deposit date: | 2019-05-20 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A novel mechanism of inhibition by phenylthiourea on PvdP, a tyrosinase synthesizing pyoverdine of Pseudomonas aeruginosa. Int.J.Biol.Macromol., 146, 2020
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3LCY
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![BU of 3lcy by Molmil](/molmil-images/mine/3lcy) | |
5OJE
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![BU of 5oje by Molmil](/molmil-images/mine/5oje) | Endothiapepsin with Ligand VSK-B24 | Descriptor: | (2~{S})-2-azanyl-3-(1~{H}-indol-3-yl)-~{N}-[2-(2,4,6-trimethylphenyl)ethyl]propanamide, DIMETHYL SULFOXIDE, Endothiapepsin, ... | Authors: | Gierse, R.M, Magari, F, Groves, M.R, Heine, A, Klebe, G, Hirsch, A. | Deposit date: | 2017-07-21 | Release date: | 2018-09-12 | Last modified: | 2018-11-21 | Method: | X-RAY DIFFRACTION (1.579 Å) | Cite: | Design and Synthesis of Bioisosteres of Acylhydrazones as Stable Inhibitors of the Aspartic Protease Endothiapepsin. ChemMedChem, 13, 2018
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