6EOD
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6G1M
| Amine Dehydrogenase from Petrotoga mobilis; open and closed form | 分子名称: | Dihydrodipicolinate reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION | 著者 | Beloti, L, Frese, A, Mayol, O, Vaxelaire-Vergne, C, Grogan, G. | 登録日 | 2018-03-21 | 公開日 | 2019-03-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | A family of native amine dehydrogenases for the asymmetric reductive amination of ketones Nat Catal, 2019
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6G1H
| Amine Dehydrogenase from Petrotoga mobilis; open form | 分子名称: | 1,2-ETHANEDIOL, Dihydrodipicolinate reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Beloti, L, Frese, A, Mayol, O, Vergne-Vaxelaire, C, Grogan, G. | 登録日 | 2018-03-21 | 公開日 | 2019-03-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | A family of native amine dehydrogenases for the asymmetric reductive amination of ketones Nat Catal, 2019
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6GIO
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6H1B
| Structure of amide bond synthetase Mcba K483A mutant from Marinactinospora thermotolerans | 分子名称: | 1-ethanoyl-9~{H}-pyrido[3,4-b]indole-3-carboxylic acid, ADENOSINE MONOPHOSPHATE, Fatty acid CoA ligase | 著者 | Rowlinson, B, Petchey, M, Cuetos, A, Frese, A, Dannevald, S, Grogan, G. | 登録日 | 2018-07-11 | 公開日 | 2018-09-05 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The Broad Aryl Acid Specificity of the Amide Bond Synthetase McbA Suggests Potential for the Biocatalytic Synthesis of Amides. Angew. Chem. Int. Ed. Engl., 57, 2018
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6G71
| Structure of CYP1232A24 from Arthrobacter sp. | 分子名称: | 1,2-ETHANEDIOL, Cytochrome P450, FE (III) ION, ... | 著者 | Dubiel, P, Sharma, M, Klenk, J, Hauer, B, Grogan, G. | 登録日 | 2018-04-04 | 公開日 | 2019-03-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Identification and characterization of cytochrome P450 1232A24 and 1232F1 from Arthrobacter sp. and their role in the metabolic pathway of papaverine. J.Biochem., 166, 2019
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6RYZ
| SalL with S-adenosyl methionine | 分子名称: | 1,2-ETHANEDIOL, Adenosyl-chloride synthase, CHLORIDE ION, ... | 著者 | McKean, I, Frese, A, Cuetos, A, Burley, G, Grogan, G. | 登録日 | 2019-06-12 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | S-Adenosyl Methionine Cofactor Modifications Enhance the Biocatalytic Repertoire of Small Molecule C-Alkylation. Angew.Chem.Int.Ed.Engl., 58, 2019
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6RZ2
| SalL with Chloroadenosine | 分子名称: | 5'-CHLORO-5'-DEOXYADENOSINE, Adenosyl-chloride synthase | 著者 | McKean, I, Frese, A, Cuetos, A, Burley, G, Grogan, G. | 登録日 | 2019-06-12 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | S-Adenosyl Methionine Cofactor Modifications Enhance the Biocatalytic Repertoire of Small Molecule C-Alkylation. Angew.Chem.Int.Ed.Engl., 58, 2019
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5FR9
| Structure of transaminase ATA-117 arRmut11 from Arthrobacter sp. KNK168 inhibited with 1-(4-Bromophenyl)-2-fluoroethylamine | 分子名称: | (R)-AMINE TRANSAMINASE, [4-[3-(4-bromophenyl)-3-oxidanylidene-propyl]-6-methyl-5-oxidanyl-pyridin-3-yl]methyl phosphate | 著者 | Cuetos, A, Kroutil, W, Lavandera, I, Grogan, G. | 登録日 | 2015-12-16 | 公開日 | 2016-03-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Catalytic Promiscuity of Transaminases: Preparation of Enantioenriched Beta-Fluoroamines by Formal Tandem Hydrodefluorination/Deamination. Angew.Chem.Int.Ed.Engl., 55, 2016
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5FYF
| Structure of CYP153A from Marinobacter aquaeolei | 分子名称: | 1,2-ETHANEDIOL, CYTOCHROME P450, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Danesh Azari, H.R, Spandolf, C, Hoffman, S.M, Weissenborn, M, Hauer, B, Grogan, G. | 登録日 | 2016-03-07 | 公開日 | 2017-01-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Structure-Guided Redesign of CYP153AM.aqfor the Improved Terminal Hydroxylation of Fatty Acids Chemcatchem, 2016
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4BMN
| apo structure of short-chain alcohol dehydrogenase from Ralstonia sp. DSM 6428 | 分子名称: | 1,2-ETHANEDIOL, ALCLOHOL DEHYDROGENASE/SHORT-CHAIN DEHYDROGENASE, TRIS(HYDROXYETHYL)AMINOMETHANE | 著者 | Man, H, Kulig, J, Rother, D, Grogan, G. | 登録日 | 2013-05-10 | 公開日 | 2014-03-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structures of Alcohol Dehydrogenases from Ralstonia and Sphingobium Spp. Reveal the Molecular Basis for Their Recognition of 'Bulky-Bulky' Ketones Top.Catal., 57, 2014
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5FYG
| Structure of CYP153A from Marinobacter aquaeolei in complex with hydroxydodecanoic acid | 分子名称: | 12-HYDROXYDODECANOIC ACID, CYTOCHROME P450, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Danesh-Azari, H.-R, Spandolf, C, Hoffman, S.M, Weissenborn, M, Hauer, B, Grogan, G. | 登録日 | 2016-03-07 | 公開日 | 2017-01-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Structure-Guided Redesign of CYP153AM.aqfor the Improved Terminal Hydroxylation of Fatty Acids Chemcatchem, 2016
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5G4I
| PLP-dependent phospholyase A1RDF1 from Arthrobacter aurescens TC1 | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, PHOSPHATE ION, ... | 著者 | Cuetos, A, Tuan, A.N, Mangas Sanchez, J, Grogan, G. | 登録日 | 2016-05-13 | 公開日 | 2016-10-19 | 最終更新日 | 2017-03-01 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural Basis for Phospholyase Activity of a Class III Transaminase Homologue. Chembiochem, 17, 2016
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5G5A
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5G1V
| Linalool Dehydratase Isomerase: Selenomethionine Derivative | 分子名称: | LINALOOL DEHYDRATASE ISOMERASE | 著者 | Chambers, S, Hau, A, Man, H, Omar, M, Turkenburg, J.P, Grogan, G. | 登録日 | 2016-03-30 | 公開日 | 2017-01-11 | 最終更新日 | 2017-02-22 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Structural and functional insights into asymmetric enzymatic dehydration of alkenols. Nat. Chem. Biol., 13, 2017
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4D3F
| BcSIRED from Bacillus cereus in complex with NADPH | 分子名称: | IMINE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Man, H, Hart, S, Turkenburg, J.P, Grogan, G. | 登録日 | 2014-10-21 | 公開日 | 2015-04-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Structure, Activity and Stereoselectivity of Nadph-Dependent Oxidoreductases Catalysing the S-Selective Reduction of the Imine Substrate 2-Methylpyrroline. Chembiochem, 16, 2015
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4CY6
| apo structure of 2-hydroxybiphenyl 3-monooxygenase HbpA | 分子名称: | 2-HYDROXYBIPHENYL-3-MONOOXYGENASE | 著者 | Jensen, C.N, Farrugia, J.E, Frank, A, Man, H, Hart, S, Turkenburg, J.P, Grogan, G. | 登録日 | 2014-04-10 | 公開日 | 2015-03-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Structures of the Apo and Fad-Bound Forms of 2-Hydroxybiphenyl 3-Monooxygenase (Hbpa) Locate Activity Hotspots Identified by Using Directed Evolution. Chembiochem, 16, 2015
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4D3D
| Structure of Imine Reductase BcSIRED from Bacillus cereus BAG3X2 | 分子名称: | IMINE REDUCTASE, MAGNESIUM ION, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL | 著者 | Man, H, Hart, S, Turkenburg, J.P, Grogan, G. | 登録日 | 2014-10-21 | 公開日 | 2015-04-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Structure, Activity and Stereoselectivity of Nadph-Dependent Oxidoreductases Catalysing the S-Selective Reduction of the Imine Substrate 2-Methylpyrroline. Chembiochem, 16, 2015
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5G1W
| Apo Structure of Linalool Dehydratase-Isomerase | 分子名称: | 1,2-ETHANEDIOL, LINALOOL DEHYDRATASE/ISOMERASE, METHYLMALONIC ACID | 著者 | Chambers, S, Hau, A, Man, H, Omar, M, Turkenburg, J.P, Grogan, G. | 登録日 | 2016-03-30 | 公開日 | 2017-01-11 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Structural and functional insights into asymmetric enzymatic dehydration of alkenols. Nat. Chem. Biol., 13, 2017
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4ATP
| Structure of GABA-transaminase A1R958 from Arthrobacter aurescens in complex with PLP | 分子名称: | 4-AMINOBUTYRATE TRANSAMINASE, PYRIDOXAL-5'-PHOSPHATE | 著者 | Bruce, H, Tuan, A.N, Mangas Sanchez, J, Hart, S, Turkenburg, J.P, Grogan, G. | 登録日 | 2012-05-09 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of a Gamma-Aminobutyrate (Gaba) Transaminase from the S-Triazine-Degrading Organism Arthrobacter Aurescens Tc1 in Complex with Plp and with its External Aldimine Plp- Gaba Adduct. Acta Crystallogr.,Sect.F, 68, 2012
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4D3S
| Imine reductase from Nocardiopsis halophila | 分子名称: | IMINE REDUCTASE, octyl beta-D-glucopyranoside | 著者 | Man, H, Hart, S, Turkenburg, J.P, Grogan, G. | 登録日 | 2014-10-23 | 公開日 | 2015-04-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Structure, Activity and Stereoselectivity of Nadph-Dependent Oxidoreductases Catalysing the S-Selective Reduction of the Imine Substrate 2-Methylpyrroline. Chembiochem, 16, 2015
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4ATQ
| GABA-transaminase A1R958 in complex with external aldimine PLP-GABA adduct | 分子名称: | 4-AMINOBUTYRATE TRANSAMINASE, GAMMA-AMINO-BUTANOIC ACID, PYRIDOXAL-5'-PHOSPHATE | 著者 | Bruce, H, Tuan, A.N, Mangas Sanchez, J, Hart, S, Turkenburg, J.P, Grogan, G. | 登録日 | 2012-05-09 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structures of a Gamma-Aminobutyrate (Gaba) Transaminase from the S-Triazine-Degrading Organism Arthrobacter Aurescens Tc1 in Complex with Plp and with its External Aldimine Plp- Gaba Adduct. Acta Crystallogr.,Sect.F, 68, 2012
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4CY8
| 2-hydroxybiphenyl 3-monooxygenase (HbpA) in complex with FAD | 分子名称: | 2-HYDROXYBIPHENYL 3-MONOOXYGENASE, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE | 著者 | Jensen, C.N, Farrugia, J.E, Frank, A, Man, H, Hart, S, Turkenburg, J.P, Grogan, G. | 登録日 | 2014-04-10 | 公開日 | 2015-03-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structures of the Apo and Fad-Bound Forms of 2-Hydroxybiphenyl 3-Monooxygenase (Hbpa) Locate Activity Hotspots Identified by Using Directed Evolution. Chembiochem, 16, 2015
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5G4J
| Phospholyase A1RDF1 from Arthrobacter in complex with phosphoethanolamine | 分子名称: | PUTATIVE AMINOTRANSFERASE CLASS III PROTEIN, SODIUM ION, {5-hydroxy-6-methyl-4-[(E)-{[2-(phosphonooxy)ethyl]imino}methyl]pyridin-3-yl}methyl dihydrogen phosphate | 著者 | Cuetos, A, Tuan, A.N, Mangas Sanchez, J, Grogan, G. | 登録日 | 2016-05-13 | 公開日 | 2016-10-19 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structural Basis for Phospholyase Activity of a Class III Transaminase Homologue. Chembiochem, 17, 2016
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5G1U
| Linalool Dehydratase Isomerase in complex with Geraniol | 分子名称: | Geraniol, LINALOOL DEHYDRATASE/ISOMERASE | 著者 | Chambers, S, Hau, A, Man, H, Omar, M, Turkenburg, J.P, Grogan, G. | 登録日 | 2016-03-30 | 公開日 | 2017-01-11 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | Structural and functional insights into asymmetric enzymatic dehydration of alkenols. Nat. Chem. Biol., 13, 2017
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