4FQN
 
 | | Crystal structure of the CCM2 C-terminal Harmonin Homology Domain (HHD) | | Descriptor: | Malcavernin | | Authors: | Fisher, O.S, Zhang, R, Li, X, Murphy, J.W, Boggon, T.J. | | Deposit date: | 2012-06-25 | | Release date: | 2012-12-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural studies of cerebral cavernous malformations 2 (CCM2) reveal a folded helical domain at its C-terminus.
Febs Lett., 587, 2013
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6CPD
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8UM6
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6P1F
 | | apo PmoF2 PCuAC domain | | Descriptor: | Copper chaperone PCu(A)C | | Authors: | Fisher, O.S, Sendzik, M.R, Rosenzweig, A.C. | | Deposit date: | 2019-05-19 | | Release date: | 2019-09-25 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.654 Å) | | Cite: | PCuAC domains from methane-oxidizing bacteria use a histidine brace to bind copper.
J.Biol.Chem., 294, 2019
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6P1E
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6P1G
 | | Copper-bound PCuAC domain from PmoF2 | | Descriptor: | COPPER (II) ION, Copper chaperone PCu(A)C, ZINC ION | | Authors: | Fisher, O.S, Rosenzweig, A.C. | | Deposit date: | 2019-05-19 | | Release date: | 2019-09-25 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | PCuAC domains from methane-oxidizing bacteria use a histidine brace to bind copper.
J.Biol.Chem., 294, 2019
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4WJ7
 | | CCM2 PTB domain in complex with KRIT1 NPxY/F3 | | Descriptor: | KRIT1 NPxY/F3, Malcavernin | | Authors: | Fisher, O.S, Liu, W, Zhang, R, Stiegler, A.L, Boggon, T.J. | | Deposit date: | 2014-09-29 | | Release date: | 2014-12-24 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.753 Å) | | Cite: | Structural Basis for the Disruption of the Cerebral Cavernous Malformations 2 (CCM2) Interaction with Krev Interaction Trapped 1 (KRIT1) by Disease-associated Mutations.
J.Biol.Chem., 290, 2015
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4Y5O
 | | CCM2 HHD in complex with MEKK3 NPB1 | | Descriptor: | Malcavernin, Mitogen-activated protein kinase kinase kinase 3 | | Authors: | Fisher, O.S, Boggon, T.J. | | Deposit date: | 2015-02-11 | | Release date: | 2015-07-01 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structure and vascular function of MEKK3-cerebral cavernous malformations 2 complex.
Nat Commun, 6, 2015
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4TVQ
 | | CCM3 in complex with CCM2 LD-like motif | | Descriptor: | Cerebral cavernous malformations 2 protein, Cerebral cavernous malformations 3 protein | | Authors: | Li, X, Zhang, R, Fisher, O.S, Boggon, T.J. | | Deposit date: | 2014-06-27 | | Release date: | 2015-03-25 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | CCM2-CCM3 interaction stabilizes their protein expression and permits endothelial network formation.
J.Cell Biol., 208, 2015
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6P17
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6P16
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7ME6
 | | Structure of the apo form of YcnI | | Descriptor: | MALONATE ION, Uncharacterized protein YcnI | | Authors: | Damle, M, Fisher, O.S. | | Deposit date: | 2021-04-06 | | Release date: | 2021-08-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.053 Å) | | Cite: | The YcnI protein from Bacillus subtilis contains a copper-binding domain.
J.Biol.Chem., 297, 2021
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7MEK
 | | Structure of copper bound to Ycnl | | Descriptor: | COPPER (II) ION, Uncharacterized protein YcnI | | Authors: | Damle, M, Fisher, O.S. | | Deposit date: | 2021-04-06 | | Release date: | 2021-08-18 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | The YcnI protein from Bacillus subtilis contains a copper-binding domain.
J.Biol.Chem., 297, 2021
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