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PDB: 103 件

1M0O
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Structure of Dialkylglycine Decarboxylase Complexed with 1-Amino-1-methylpropanephosphonate
分子名称: (1R)-1-[((1E)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLENE)AMINO]-1-METHYLPROPYLPHOSPHONIC ACID, 2,2-Dialkylglycine decarboxylase, POTASSIUM ION, ...
著者Liu, W, Rogers, C.J, Fisher, A.J, Toney, M.D.
登録日2002-06-13
公開日2002-10-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Aminophosphonate Inhibitors of Dialkylglycine Decarboxylase: Structural Basis for Slow Binding Inhibition
Biochemistry, 41, 2002
1NC2
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Crystal Structure of Monoclonal Antibody 2D12.5 Fab Complexed with Y-DOTA
分子名称: (S)-2-(4-(2-(2-HYDROXYETHYLTHIO)-ACETAMIDO)-BENZYL)-1,4,7,10-TETRAAZACYCLODODECANE-N,N',N'',N'''-TETRAACETATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Corneillie, T.M, Fisher, A.J, Meares, C.F.
登録日2002-12-04
公開日2003-12-16
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of two complexes of the rare-earth-DOTA-binding antibody 2D12.5: ligand generality from a chiral system.
J.Am.Chem.Soc., 125, 2003
5DJF
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Structure of M. tuberculosis CysQ, a PAP phosphatase - ligand-free structure
分子名称: 3'-phosphoadenosine 5'-phosphate phosphatase, GLYCEROL, SODIUM ION
著者Erickson, A.I, Fisher, A.J.
登録日2015-09-02
公開日2015-11-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structures of Mycobacterium tuberculosis CysQ, with Substrate and Products Bound.
Biochemistry, 54, 2015
1M8P
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Crystal Structure of P. chrysogenum ATP Sulfurylase in the T-state
分子名称: 3'-PHOSPHATE-ADENOSINE-5'-PHOSPHATE SULFATE, sulfate adenylyltransferase
著者MacRae, I.J, Segel, I.H, Fisher, A.J.
登録日2002-07-25
公開日2002-11-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Allosteric Inhibition via R-State Destabilization in ATP Sulfurylase from Penicillium chrysogenum
Nat.Struct.Biol., 9, 2002
1M0N
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Structure of Dialkylglycine Decarboxylase Complexed with 1-Aminocyclopentanephosphonate
分子名称: 1-[((1E)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLENE)AMINO]CYCLOPENTYLPHOSPHONIC ACID, 2,2-Dialkylglycine decarboxylase, POTASSIUM ION, ...
著者Liu, W, Rogers, C.J, Fisher, A.J, Toney, M.D.
登録日2002-06-13
公開日2002-10-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Aminophosphonate Inhibitors of Dialkylglycine Decarboxylase: Structural Basis for Slow Binding Inhibition
Biochemistry, 41, 2002
1NC4
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Crystal Structure of Monoclonal Antibody 2D12.5 Fab Complexed with Gd-DOTA
分子名称: (S)-2-(4-NITROBENZYL)-1,4,7,10-TETRAAZACYCLODODECANE-N,N',N'',N'''-TETRAACETATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Corneillie, T.M, Fisher, A.J, Meares, C.F.
登録日2002-12-04
公開日2003-12-16
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structures of two complexes of the rare-earth-DOTA-binding antibody 2D12.5: ligand generality from a chiral system.
J.Am.Chem.Soc., 125, 2003
1SF2
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Structure of E. coli gamma-aminobutyrate aminotransferase
分子名称: 1,2-ETHANEDIOL, 4-aminobutyrate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ...
著者Liu, W, Peterson, P.E, Carter, R.J, Zhou, X, Langston, J.A, Fisher, A.J, Toney, M.D.
登録日2004-02-19
公開日2004-09-14
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of unbound and aminooxyacetate-bound Escherichia coli gamma-aminobutyrate aminotransferase.
Biochemistry, 43, 2004
5ED2
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Human Adenosine Deaminase Acting on dsRNA (ADAR2) mutant E488Q bound to dsRNA sequence derived from human GLI1 gene
分子名称: Double-stranded RNA-specific editase 1, INOSITOL HEXAKISPHOSPHATE, RNA (5'-R(P*CP*AP*GP*AP*GP*CP*CP*CP*CP*CP*CP*AP*GP*CP*AP*UP*CP*GP*CP*GP*AP*GP*C)-3'), ...
著者Matthews, M.M, Fisher, A.J.
登録日2015-10-20
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity.
Nat.Struct.Mol.Biol., 23, 2016
5ED1
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Human Adenosine Deaminase Acting on dsRNA (ADAR2) mutant E488Q bound to dsRNA sequence derived from S. cerevisiae BDF2 gene
分子名称: Double-stranded RNA-specific editase 1, INOSITOL HEXAKISPHOSPHATE, RNA (5'-R(*GP*AP*CP*UP*GP*AP*AP*CP*GP*AP*CP*CP*AP*AP*UP*GP*UP*GP*GP*GP*GP*AP*A)-3'), ...
著者Matthews, M.M, Fisher, A.J, Beal, P.A.
登録日2015-10-20
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity.
Nat.Struct.Mol.Biol., 23, 2016
1M72
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Crystal Structure of Caspase-1 from Spodoptera frugiperda
分子名称: 1,2-ETHANEDIOL, Ace-Asp-Glu-Val-Asp-chloromethylketone, Caspase-1
著者Forsyth, C.M, Lemongello, D, Friesen, P.D, Fisher, A.J.
登録日2002-07-18
公開日2004-01-20
最終更新日2013-02-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of an invertebrate caspase.
J.Biol.Chem., 279, 2004
2GKS
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Crystal Structure of the Bi-functional ATP Sulfurylase-APS Kinase from Aquifex aeolicus, a Chemolithotrophic Thermophile
分子名称: ADENOSINE-5'-DIPHOSPHATE, Bifunctional SAT/APS kinase
著者Yu, Z, MacRea, I.J, Lansdon, E.B, Segel, I.H, Fisher, A.J.
登録日2006-04-03
公開日2007-03-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal structure of the bifunctional ATP sulfurylase-APS kinase from the chemolithotrophic thermophile Aquifex aeolicus.
J.Mol.Biol., 365, 2007
2EX1
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Crystal structure of mutifunctional sialyltransferase from Pasteurella multocida with CMP bound
分子名称: CYTIDINE-5'-MONOPHOSPHATE, a2,3-sialyltransferase, a2,a6-sialyltransferase
著者Ni, L, Sun, M, Chen, X, Fisher, A.J.
登録日2005-11-07
公開日2006-02-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cytidine 5'-Monophosphate (CMP)-Induced Structural Changes in a Multifunctional Sialyltransferase from Pasteurella multocida
Biochemistry, 45, 2006
2EX0
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Crystal structure of multifunctional sialyltransferase from Pasteurella Multocida
分子名称: a2,3-sialyltransferase, a2,6-sialyltransferase
著者Ni, L, Sun, M, Chen, X, Fisher, A.J.
登録日2005-11-07
公開日2006-02-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Cytidine 5'-Monophosphate (CMP)-Induced Structural Changes in a Multifunctional Sialyltransferase from Pasteurella multocida
Biochemistry, 45, 2006
1FOZ
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STRUCTURE OF CYCLIC PEPTIDE INHIBITORS OF MAMMALIAN RIBONUCLEOTIDE REDUCTASE
分子名称: SYNTHETIC CYCLIC PEPTIDE
著者Pellegrini, M, Liehr, S, Fisher, A.L, Cooperman, B.S, Mierke, D.F.
登録日2000-08-29
公開日2000-11-22
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure-based optimization of peptide inhibitors of mammalian ribonucleotide reductase.
Biochemistry, 39, 2000
2G18
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Crystal Structure of Nostoc sp. 7120 phycocyanobilin:ferredoxin oxidoreductase (PcyA) Apoprotein
分子名称: CALCIUM ION, Phycocyanobilin:ferredoxin oxidoreductase
著者Tu, S.-L, Lagarias, J.C, Fisher, A.J.
登録日2006-02-13
公開日2006-12-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Insight into the radical mechanism of phycocyanobilin-ferredoxin oxidoreductase (PcyA) revealed by X-ray crystallography and biochemical measurements.
Biochemistry, 46, 2007
8FAY
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BU of 8fay by Molmil
Human MUTYH adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G)
分子名称: Adenine DNA glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*CP*AP*(NR1)P*GP*TP*CP*T)-3'), ...
著者Trasvina-Arenas, C.H, Lin, W.J, Demir, M, Fisher, A.J, David, S.S, Horvath, M.P.
登録日2022-11-29
公開日2024-05-29
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Human MUTYH adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G)
To Be Published
4Z4A
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Avirulence protein 4 (Avr4) from Pseudocercospora fuligena
分子名称: 1,2-ETHANEDIOL, Carbohydrate-binding module family 14 protein
著者Hurlburt, N.K, Kohler, A.C, Fisher, A.J.
登録日2015-04-01
公開日2016-06-29
最終更新日2016-09-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Analysis of an Avr4 Effector Ortholog Offers Insight into Chitin Binding and Recognition by the Cf-4 Receptor.
Plant Cell, 28, 2016
4F5J
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Rational Design and Directed Evolution for Conversion of Substrate Specificity from E.coli Aspartate Aminotransferase to Tyrosine Aminotransferase: Mutant P5.
分子名称: Aspartate aminotransferase
著者Addington, T.A, Fisher, A.J, Toney, M.D.
登録日2012-05-13
公開日2013-02-13
最終更新日2013-04-24
実験手法X-RAY DIFFRACTION (1.954 Å)
主引用文献Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4F5F
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Structure of Aspartate Aminotransferase Conversion to Tyrosine Aminotransferase: Chimera P1.
分子名称: Aspartate aminotransferase
著者Addington, T.A, Fisher, A.J, Toney, M.D.
登録日2012-05-13
公開日2013-02-13
最終更新日2013-04-24
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4F5M
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Wild-Type E. coli Aspartate Aminotransferase: A Template For The Interconversion of Substrate Specificity and Activity To Tyrosine Aminotransferase By The JANUS Algorithm.
分子名称: 1,2-ETHANEDIOL, Aspartate aminotransferase
著者Addington, T.A, Fisher, A.J, Toney, M.D.
登録日2012-05-13
公開日2013-02-13
最終更新日2013-04-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4F5I
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Substrate Specificity Conversion of E. coli Pyridoxal-5'-Phosphate Dependent Aspartate Aminotransferase to Tyrosine Aminotransferase: Chimera P4.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Aspartate aminotransferase
著者Addington, T.A, Fisher, A.J, Toney, M.D.
登録日2012-05-13
公開日2013-02-13
最終更新日2013-04-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4F5H
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Intercoversion of Substrate Specificity: E. coli Aspatate Aminotransferase to Tyrosine Aminotransferase: Chimera P3.
分子名称: Aspartate aminotransferase
著者Addington, T.A, Fisher, A.J, Toney, M.D.
登録日2012-05-13
公開日2013-02-13
最終更新日2013-04-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4F5L
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A Theoretical Optimized Mutant for the Conversion of Substrate Specificity and Activity of Aspartate Aminotransferase to Tyrosine Aminotransferase: Chimera P7.
分子名称: 1,2-ETHANEDIOL, Aspartate aminotransferase
著者Addington, T.A, Fisher, A.J, Toney, M.D.
登録日2012-05-13
公開日2013-05-15
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Janus: an algorithm for ranking functional importance of residues from protein sequence alignments.
To be Published
4F5K
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Substrate Specificity Conversion of Aspartate Aminotransferase to Tyrosine Aminotransferase By The JANUS Algorithm: Chimera P6.
分子名称: Aspartate aminotransferase
著者Addington, T.A, Fisher, A.J, Toney, M.D.
登録日2012-05-13
公開日2013-02-13
最終更新日2013-04-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4F5G
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Rational Design and Directed Evolution of E. coli Apartate Aminotransferase to Tyrosine Aminotransferase: Mutant P2.
分子名称: Aspartate aminotransferase
著者Addington, T.A, Fisher, A.J, Toney, M.D.
登録日2012-05-13
公開日2013-02-13
最終更新日2013-04-24
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013

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件を2024-09-11に公開中

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