7CMW
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![BU of 7cmw by Molmil](/molmil-images/mine/7cmw) | Complex structure of PARP1 catalytic domain with pamiparib | 分子名称: | (2R)-14-fluoro-2-methyl-6,9,10,19-tetrazapentacyclo[14.2.1.02,6.08,18.012,17]nonadeca-1(18),8,12(17),13,15-pentaen-11-one, GLYCEROL, Poly [ADP-ribose] polymerase 1 | 著者 | Feng, Y.C, Peng, H, Hong, Y, Liu, Y. | 登録日 | 2020-07-29 | 公開日 | 2020-12-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Discovery of Pamiparib (BGB-290), a Potent and Selective Poly (ADP-ribose) Polymerase (PARP) Inhibitor in Clinical Development. J.Med.Chem., 63, 2020
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7CGW
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![BU of 7cgw by Molmil](/molmil-images/mine/7cgw) | Complex structure of PD-1 and tislelizumab Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of tislelizumab Fab, Light chain of tislelizumab Fab, ... | 著者 | Hong, Y, Feng, Y.C, Liu, Y. | 登録日 | 2020-07-02 | 公開日 | 2021-04-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Tislelizumab uniquely binds to the CC' loop of PD-1 with slow-dissociated rate and complete PD-L1 blockage. Febs Open Bio, 11, 2021
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