9GBH
 
 | | CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH COMPOUND1 | | 分子名称: | 2-(3,4-dimethoxyphenyl)-3,5-bis(oxidanylidene)-4-[[3-(trifluoromethyl)phenyl]methyl]-1,2,4-triazine-6-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chymase, ... | | 著者 | Schaefer, M, Fuerstner, C, Ackerstaff, J, Meier, H, Straub, A, Mittendorf, J, Schamberger, J, Boerngen, K, Joerissen, H, Zubow, D, Zimmermann, K, Tersteegen, A, Geiss, V, Hartmann, E, Albrecht-Kuepper, B, Dorleans-Juste, P, Lapointe, C, Vincent, L, Heitmeier, S, Tinel, H. | | 登録日 | 2024-07-31 | | 公開日 | 2024-11-27 | | 実験手法 | X-RAY DIFFRACTION (2.375 Å) | | 主引用文献 | Discovery and Preclinical Characterization of Fulacimstat (BAY 1142524), a Potent and Selective Chymase Inhibitor As a New Profibrinolytic Approach for Safe Thrombus Resolution.
J.Med.Chem., 2024
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