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PDB: 188 件
6FVQ
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BU of 6fvq by Molmil
The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - R86A
分子名称: Cys-loop ligand-gated ion channel, TETRAETHYLENE GLYCOL, nonyl beta-D-glucopyranoside
著者Hu, H, Delarue, M.
登録日2018-03-05
公開日2018-05-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HYW
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BU of 6hyw by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Y119F
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HPP
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BU of 6hpp by Molmil
X-ray structure of GLIC in complex with propionate
分子名称: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, PROPANOIC ACID, ...
著者Fourati, Z, Delarue, M.
登録日2018-09-21
公開日2019-10-09
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel.
Acta Crystallogr D Struct Biol, 76, 2020
6HZ0
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BU of 6hz0 by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT K248A
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HZW
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BU of 6hzw by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL 2.22 resolution
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-24
公開日2018-12-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HY5
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BU of 6hy5 by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193C
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-19
公開日2018-12-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HYV
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BU of 6hyv by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Y119A
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HYR
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BU of 6hyr by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193C+MMTS
分子名称: DODECYL-BETA-D-MALTOSIDE, Proton-gated ion channel
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2025-04-09
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HJB
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BU of 6hjb by Molmil
Xray structure of GLIC in complex with malonate
分子名称: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ...
著者Fourati, Z, Delarue, M.
登録日2018-09-03
公開日2019-09-18
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel.
Acta Crystallogr D Struct Biol, 76, 2020
6HJZ
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BU of 6hjz by Molmil
Xray structure of GLIC in complex with succinate
分子名称: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ...
著者Fourati, Z, Delarue, M.
登録日2018-09-04
公開日2019-09-18
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel.
Acta Crystallogr D Struct Biol, 76, 2020
6HY9
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BU of 6hy9 by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193M
分子名称: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Proton-gated ion channel
著者Hu, H.D, Delarue, M.
登録日2018-10-19
公開日2018-12-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HYA
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BU of 6hya by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193L
分子名称: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Proton-gated ion channel
著者Hu, H.D, Delarue, M.
登録日2018-10-19
公開日2018-12-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.39 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HYZ
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BU of 6hyz by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT K248C
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6I08
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BU of 6i08 by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT E243C-I201W
分子名称: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-25
公開日2018-12-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HZ3
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BU of 6hz3 by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT E243G
分子名称: CHLORIDE ION, Proton-gated ion channel
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HZ1
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BU of 6hz1 by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT E243C
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HJI
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BU of 6hji by Molmil
Xray structure of GLIC in complex with crotonate
分子名称: BUTENOIC ACID, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Fourati, Z, Delarue, M.
登録日2018-09-03
公開日2019-09-18
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel.
Acta Crystallogr D Struct Biol, 76, 2020
6HJ3
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BU of 6hj3 by Molmil
Xray structure of GLIC in complex with fumarate
分子名称: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ...
著者Fourati, Z, Delarue, M.
登録日2018-08-31
公開日2019-09-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel.
Acta Crystallogr D Struct Biol, 76, 2020
6HJA
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BU of 6hja by Molmil
Xray structure of GLIC in complex with glutarate
分子名称: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECANE, ...
著者Fourati, Z, Delarue, M.
登録日2018-09-03
公開日2019-09-18
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel.
Acta Crystallogr D Struct Biol, 76, 2020
6HYX
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BU of 6hyx by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Y197F-P250C
分子名称: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Proton-gated ion channel, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4I2B
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BU of 4i2b by Molmil
Ternary complex of mouse TdT with ssDNA and AMPcPP
分子名称: 5'-D(P*AP*AP*AP*AP*A)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
4I2A
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BU of 4i2a by Molmil
Binary complex of mouse TdT with ssDNA in absence of divalent transition metal ion
分子名称: 5'-D(*AP*AP*(BRU)P*AP*A)-3', DNA nucleotidylexotransferase, MAGNESIUM ION, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
4I2G
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BU of 4i2g by Molmil
Binary complex of mouse TdT with ssDNA
分子名称: 5'-D(P*AP*AP*AP*AP*A)-3', COBALT (II) ION, DNA nucleotidylexotransferase, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
4I2H
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BU of 4i2h by Molmil
Ternary complex of mouse TdT with ssDNA and AMPcPP
分子名称: 5'-D(P*AP*AP*AP*AP*A)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
4I2J
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BU of 4i2j by Molmil
Binary complex of mouse TdT with dCTP
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA nucleotidylexotransferase, ZINC ION
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013

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件を2025-06-04に公開中

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