3MQ3
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8EW5
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![BU of 8ew5 by Molmil](/molmil-images/mine/8ew5) | The structure of flightin within myosin thick filaments from Bombus ignitus flight muscle | 分子名称: | Flightin | 著者 | Li, J, Rahmani, H, Abbasi Yeganeh, F, Rastegarpouyani, H, Taylor, D.W, Wood, N.B, Previs, M.J, Iwamoto, H, Taylor, K.A. | 登録日 | 2022-10-21 | 公開日 | 2023-01-04 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Structure of the Flight Muscle Thick Filament from the Bumble Bee, Bombus ignitus , at 6 angstrom Resolution. Int J Mol Sci, 24, 2022
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4Q3P
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![BU of 4q3p by Molmil](/molmil-images/mine/4q3p) | Crystal structure of Schistosoma mansoni arginase | 分子名称: | Arginase, GLYCEROL, MANGANESE (II) ION | 著者 | Hai, Y, Edwards, J.E, Van Zandt, M.C, Hoffmann, K.F, Christianson, D.W. | 登録日 | 2014-04-12 | 公開日 | 2014-07-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis. Biochemistry, 53, 2014
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5D1C
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![BU of 5d1c by Molmil](/molmil-images/mine/5d1c) | Crystal structure of D233G-Y306F HDAC8 in complex with a tetrapeptide substrate | 分子名称: | GLYCEROL, HDAC8 Fluor de Lys tetrapeptide substrate, Histone deacetylase 8, ... | 著者 | Decroos, C, Christianson, N.H, Gullett, L.E, Bowman, C.M, Christianson, K.E, Deardorff, M.A, Christianson, D.W. | 登録日 | 2015-08-04 | 公開日 | 2015-10-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.422 Å) | 主引用文献 | Biochemical and Structural Characterization of HDAC8 Mutants Associated with Cornelia de Lange Syndrome Spectrum Disorders. Biochemistry, 54, 2015
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4Q3V
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![BU of 4q3v by Molmil](/molmil-images/mine/4q3v) | Crystal structure of Schistosoma mansoni arginase in complex with inhibitor BEC | 分子名称: | Arginase, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Hai, Y, Edwards, J.E, Van Zandt, M.C, Hoffmann, K.F, Christianson, D.W. | 登録日 | 2014-04-12 | 公開日 | 2014-07-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis. Biochemistry, 53, 2014
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8F1B
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8EZW
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5DC7
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![BU of 5dc7 by Molmil](/molmil-images/mine/5dc7) | Crystal structure of D176A-Y306F HDAC8 in complex with a tetrapeptide substrate | 分子名称: | Fluor-de-Lys tetrapeptide assay substrate, GLYCEROL, Histone deacetylase 8, ... | 著者 | Decroos, C, Lee, M.S, Christianson, D.W. | 登録日 | 2015-08-23 | 公開日 | 2016-02-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | General Base-General Acid Catalysis in Human Histone Deacetylase 8. Biochemistry, 55, 2016
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4QA6
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![BU of 4qa6 by Molmil](/molmil-images/mine/4qa6) | Crystal structure of I243N/Y306F HDAC8 in complex with a tetrapeptide substrate | 分子名称: | 7-AMINO-4-METHYL-CHROMEN-2-ONE, GLYCEROL, Histone deacetylase 8, ... | 著者 | Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. | 登録日 | 2014-05-02 | 公開日 | 2014-08-06 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.053 Å) | 主引用文献 | Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
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5CXU
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3N0F
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3MZ6
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![BU of 3mz6 by Molmil](/molmil-images/mine/3mz6) | Crystal structure of D101L Fe2+ HDAC8 complexed with M344 | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, FE (II) ION, Histone deacetylase 8, ... | 著者 | Dowling, D.P, Gattis, S.G, Fierke, C.A, Christianson, D.W. | 登録日 | 2010-05-11 | 公開日 | 2010-06-23 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function. Biochemistry, 49, 2010
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3MZ7
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![BU of 3mz7 by Molmil](/molmil-images/mine/3mz7) | Crystal structure of D101L Co2+ HDAC8 complexed with M344 | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, COBALT (II) ION, GLYCEROL, ... | 著者 | Dowling, D.P, Gattis, S.G, Fierke, C.A, Christianson, D.W. | 登録日 | 2010-05-11 | 公開日 | 2010-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function. Biochemistry, 49, 2010
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8EQI
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3N0G
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5EB6
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5E3X
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![BU of 5e3x by Molmil](/molmil-images/mine/5e3x) | Crystal structure of thermostable Carboxypeptidase (FisCP) from Fervidobacterium Islandicum AW-1 | 分子名称: | COBALT (II) ION, Thermostable carboxypeptidase 1 | 著者 | Dhanasingh, I, Lee, Y.-J, Lee, D.W, Lee, S.H. | 登録日 | 2015-10-05 | 公開日 | 2016-02-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.197 Å) | 主引用文献 | Biochemical and structural characterization of a keratin-degrading M32 carboxypeptidase from Fervidobacterium islandicum AW-1 Biochem.Biophys.Res.Commun., 468, 2015
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5DC8
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![BU of 5dc8 by Molmil](/molmil-images/mine/5dc8) | Crystal structure of H142A-Y306F HDAC8 in complex with a tetrapeptide substrate | 分子名称: | Fluor-de-Lys tetrapeptide assay substrate, GLYCEROL, Histone deacetylase 8, ... | 著者 | Decroos, C, Lee, M.S, Christianson, D.W. | 登録日 | 2015-08-23 | 公開日 | 2016-02-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | General Base-General Acid Catalysis in Human Histone Deacetylase 8. Biochemistry, 55, 2016
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8TC9
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![BU of 8tc9 by Molmil](/molmil-images/mine/8tc9) | Human asparaginyl-tRNA synthetase bound to OSM-S-106 | 分子名称: | Asparagine--tRNA ligase, cytoplasmic, GLYCEROL, ... | 著者 | Dogovski, C, Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W. | 登録日 | 2023-06-30 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nat Commun, 15, 2024
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8TC8
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![BU of 8tc8 by Molmil](/molmil-images/mine/8tc8) | Human asparaginyl-tRNA synthetase bound to adenosine 5'-sulfamate | 分子名称: | 5'-O-[N-(L-ASPARAGINYL)SULFAMOYL]ADENOSINE, Asparagine--tRNA ligase, cytoplasmic, ... | 著者 | Dogovski, C, Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W. | 登録日 | 2023-06-30 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nat Commun, 15, 2024
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8TC7
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![BU of 8tc7 by Molmil](/molmil-images/mine/8tc7) | Human asparaginyl-tRNA synthetase, apo form | 分子名称: | Asparagine--tRNA ligase, cytoplasmic, CHLORIDE ION, ... | 著者 | Dogovski, C, Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W. | 登録日 | 2023-06-30 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nat Commun, 15, 2024
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4Q41
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![BU of 4q41 by Molmil](/molmil-images/mine/4q41) | Crystal structure of Schistosoma mansoni arginase in complex with L-lysine | 分子名称: | Arginase, GLYCEROL, LYSINE, ... | 著者 | Hai, Y, Edwards, J.E, Van Zandt, M.C, Hoffmann, K.F, Christianson, D.W. | 登録日 | 2014-04-12 | 公開日 | 2014-07-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | 主引用文献 | Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis. Biochemistry, 53, 2014
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3MS5
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![BU of 3ms5 by Molmil](/molmil-images/mine/3ms5) | Crystal Structure of Human gamma-butyrobetaine,2-oxoglutarate dioxygenase 1 (BBOX1) | 分子名称: | 1,2-ETHANEDIOL, 2-(2-carboxyethyl)-1,1,1-trimethyldiazanium, Gamma-butyrobetaine dioxygenase, ... | 著者 | Krojer, T, Kochan, G, McDonough, M.A, von Delft, F, Leung, I.K.H, Henry, L, Claridge, T.D.W, Pilka, E, Ugochukwu, E, Muniz, J, Filippakopoulos, P, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Kavanagh, K.L, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) | 登録日 | 2010-04-29 | 公開日 | 2010-05-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Structural and mechanistic studies on gamma-butyrobetaine hydroxylase. Chem. Biol., 17, 2010
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4Q3Q
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![BU of 4q3q by Molmil](/molmil-images/mine/4q3q) | Crystal structure of Schistosoma mansoni arginase in complex with inhibitor ABH | 分子名称: | 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase, GLYCEROL, ... | 著者 | Hai, Y, Edwards, J.E, Van Zandt, M.C, Hoffmann, K.F, Christianson, D.W. | 登録日 | 2014-04-12 | 公開日 | 2014-07-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis. Biochemistry, 53, 2014
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4QA2
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![BU of 4qa2 by Molmil](/molmil-images/mine/4qa2) | Crystal structure of I243N HDAC8 in complex with SAHA | 分子名称: | GLYCEROL, Histone deacetylase 8, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, ... | 著者 | Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. | 登録日 | 2014-05-02 | 公開日 | 2014-08-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.377 Å) | 主引用文献 | Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
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