4A3C
 
 | | RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid | | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | | Authors: | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | Deposit date: | 2011-09-30 | | Release date: | 2011-11-16 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4A3B
 | | RNA Polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid | | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | | Authors: | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | Deposit date: | 2011-09-30 | | Release date: | 2011-12-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4A3D
 | | RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid | | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | | Authors: | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | Deposit date: | 2011-09-30 | | Release date: | 2011-12-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4A3F
 | | RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid and soaked with AMPCPP | | Descriptor: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*DTP *TP*TP*CP*C BRU*GP*GP*TP*CP*AP*TP*T)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, ... | | Authors: | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | Deposit date: | 2011-09-30 | | Release date: | 2011-12-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4BBS
 | | Structure of an initially transcribing RNA polymerase II-TFIIB complex | | Descriptor: | 5'-D(*AP*GP*CP*GP*CP*AP*GP*TP*TP*GP*TP*GP*CP*TP *AP*TP*GP*AP*TP*AP*TP*TP*TP*TP*TP*AP*TP)-3', 5'-D(*GP*GP*CP*AP*CP*AP*AP*CP*TP*GP*CP*GP*CP*TP)-3', 5'-R(*AP*UP*AP*UP*CP*AP)-3', ... | | Authors: | Sainsbury, S, Niesser, J, Cramer, P. | | Deposit date: | 2012-09-27 | | Release date: | 2012-11-14 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structure and Function of the Initially Transcribing RNA Polymerase II-TFIIB Complex
Nature, 493, 2013
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4H61
 | | Structure of the Schizosaccharomyces pombe Mediator subunit Med6 | | Descriptor: | Mediator of RNA polymerase II transcription subunit 6 | | Authors: | Lariviere, L, Plaschka, C, Seizl, M, Wenzeck, L, Kurth, F, Cramer, P. | | Deposit date: | 2012-09-19 | | Release date: | 2012-10-31 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure of the Mediator head module.
Nature, 492, 2012
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4BXX
 | | Arrested RNA polymerase II-Bye1 complex | | Descriptor: | 5'-D(*AP*GP*CP*TP*AP*GP*CP*TP*TP*AP*CP*CP*TP*GP *GP*TP*GP* BRUP*TP*GP*CP*TP*CP*TP*AP*AP*DC)-3', 5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP)-3', 5'-D(*GP*AP*GP*GP*TP*AP*AP*GP*CP*TP*AP*GP*CP*TP)-3', ... | | Authors: | Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. | | Deposit date: | 2013-07-16 | | Release date: | 2013-09-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.28 Å) | | Cite: | Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue
Proc.Natl.Acad.Sci.USA, 110, 2013
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3TJ1
 | | Crystal Structure of RNA Polymerase I Transcription Initiation Factor Rrn3 | | Descriptor: | RNA polymerase I-specific transcription initiation factor RRN3 | | Authors: | Blattner, C, Jennebach, S, Herzog, F, Mayer, A, Cheung, A.C.M, Witte, G, Lorenzen, K, Hopfner, K.-P, Heck, A.J.R, Aebersold, R, Cramer, P. | | Deposit date: | 2011-08-23 | | Release date: | 2011-09-28 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth.
Genes Dev., 25, 2011
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6T9K
 | | SAGA Core module | | Descriptor: | Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ... | | Authors: | Wang, H, Cheung, A, Cramer, P. | | Deposit date: | 2019-10-28 | | Release date: | 2020-01-29 | | Last modified: | 2020-02-19 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of the transcription coactivator SAGA.
Nature, 577, 2020
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6T9J
 | | SAGA Tra1 module | | Descriptor: | Transcription factor SPT20, Transcription initiation factor TFIID subunit 12, Transcription-associated protein 1 | | Authors: | Wang, H, Cheung, A, Cramer, P. | | Deposit date: | 2019-10-28 | | Release date: | 2020-01-29 | | Last modified: | 2020-02-19 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of the transcription coactivator SAGA.
Nature, 577, 2020
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6T9I
 | | cryo-EM structure of transcription coactivator SAGA | | Descriptor: | Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ... | | Authors: | Wang, H, Cheung, A, Cramer, P. | | Deposit date: | 2019-10-28 | | Release date: | 2020-01-29 | | Last modified: | 2020-02-19 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structure of the transcription coactivator SAGA.
Nature, 577, 2020
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4A3J
 | | RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid and soaked with GMPCPP | | Descriptor: | 5'-D(*AP*GP*CP*TP*AP*GP*CP*TP*TP*TP*CP*BRUP*AP*CP*CP *TP*GP*AP*AP*CP*AP*AP*CP*TP*AP*AP*CP)-3', 5'-D(*GP*TP*AP*GP*AP*AP*AP*GP*CP*TP*AP*GP*CP*TP)-3', 5'-R(*CP*AP)-3', ... | | Authors: | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | Deposit date: | 2011-09-30 | | Release date: | 2011-12-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Structural Basis of Initial RNA Polymerase II Transcription.
Embo J., 30, 2011
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4A3G
 | | RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid | | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | | Authors: | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | Deposit date: | 2011-09-30 | | Release date: | 2012-02-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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2C5Z
 | | Structure and CTD binding of the Set2 SRI domain | | Descriptor: | SET DOMAIN PROTEIN 2 | | Authors: | Vojnic, E, Simon, B, Strahl, B.D, Sattler, M, Cramer, P. | | Deposit date: | 2005-11-03 | | Release date: | 2005-11-14 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription.
J. Biol. Chem., 281, 2006
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3QT1
 | | RNA polymerase II variant containing A Chimeric RPB9-C11 subunit | | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | Authors: | Ruan, W, Lehmann, E, Thomm, M, Kostrewa, D, Cramer, P. | | Deposit date: | 2011-02-22 | | Release date: | 2011-03-23 | | Last modified: | 2017-08-23 | | Method: | X-RAY DIFFRACTION (4.3 Å) | | Cite: | Evolution of two modes of intrinsic RNA polymerase transcript cleavage.
J.Biol.Chem., 286, 2011
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5M3F
 | | Yeast RNA polymerase I elongation complex at 3.8A | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Neyer, S, Kunz, M, Geiss, C, Hantsche, M, Hodirnau, V.-V, Seybert, A, Engel, C, Scheffer, M.P, Cramer, P, Frangakis, A.S. | | Deposit date: | 2016-10-14 | | Release date: | 2016-11-23 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure of RNA polymerase I transcribing ribosomal DNA genes.
Nature, 540, 2016
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1Y14
 | | Crystal structure of yeast subcomplex of Rpb4 and Rpb7 | | Descriptor: | DNA-directed RNA polymerase II 19 kDa polypeptide, DNA-directed RNA polymerase II 32 kDa polypeptide | | Authors: | Armache, K.-J, Mitterweger, S, Meinhart, A, Cramer, P. | | Deposit date: | 2004-11-17 | | Release date: | 2004-12-14 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structures of Complete RNA Polymerase II and Its Subcomplex, Rpb4/7
J.Biol.Chem., 280, 2005
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3QWD
 | | Crystal structure of ClpP from Staphylococcus aureus | | Descriptor: | ATP-dependent Clp protease proteolytic subunit, CHLORIDE ION | | Authors: | Geiger, S.R, Boettcher, T, Sieber, S.A, Cramer, P. | | Deposit date: | 2011-02-28 | | Release date: | 2011-05-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A Conformational Switch Underlies ClpP Protease Function.
Angew.Chem.Int.Ed.Engl., 50, 2011
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4A3I
 | | RNA Polymerase II binary complex with DNA | | Descriptor: | 5'-D(*GP*GP*CP*AP*CP*AP*AP*CP*TP*GP*CP*GP*GP*CP*T)-3', DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ... | | Authors: | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | Deposit date: | 2011-09-30 | | Release date: | 2012-02-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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3M1M
 | | Crystal structure of the primase-polymerase from Sulfolobus islandicus | | Descriptor: | GLYCEROL, ORF904, SULFATE ION, ... | | Authors: | Vannini, A, Beck, K, Lipps, G, Cramer, P. | | Deposit date: | 2010-03-05 | | Release date: | 2010-06-16 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The archaeo-eukaryotic primase of plasmid pRN1 requires a helix bundle domain for faithful primer synthesis
Nucleic Acids Res., 38, 2010
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6R80
 | | Structure of AFF4 C-terminal homology domain | | Descriptor: | AF4/FMR2 family member 4 | | Authors: | Chen, Y, Cramer, P. | | Deposit date: | 2019-03-30 | | Release date: | 2019-06-12 | | Last modified: | 2019-07-17 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of the super-elongation complex subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization.
J.Biol.Chem., 294, 2019
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1YKH
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6RIC
 | | Structure of the core Vaccinia Virus DNA-dependent RNA polymerase complex | | Descriptor: | DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ... | | Authors: | Grimm, C, Hillen, H.S, Bedenk, K, Bartuli, J, Neyer, S, Zhang, Q, Huettenhofer, A, Erlacher, M, Dienemann, C, Schlosser, A, Urlaub, H, Boettcher, B, Szalay, A, Cramer, P, Fischer, U. | | Deposit date: | 2019-04-23 | | Release date: | 2019-12-18 | | Last modified: | 2019-12-25 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes.
Cell, 179, 2019
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5N61
 | | RNA polymerase I initially transcribing complex | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P. | | Deposit date: | 2017-02-14 | | Release date: | 2017-04-05 | | Last modified: | 2019-10-02 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural Basis of RNA Polymerase I Transcription Initiation.
Cell, 169, 2017
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1ZP2
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