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PDB: 5 results

9CPG
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BU of 9cpg by Molmil
Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1
Descriptor: 4-carbamimidamidophenyl 4-carbamimidamidobenzoate, RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3')
Authors:Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L.
Deposit date:2024-07-18
Release date:2024-08-07
Method:SOLUTION NMR
Cite:Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1.
Bioorg.Med.Chem.Lett., 2024
9CPD
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BU of 9cpd by Molmil
Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1
Descriptor: 4-[(3-methoxyphenyl)amino]-2-methylquinoline-6-carboximidamide, RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3')
Authors:Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L.
Deposit date:2024-07-18
Release date:2024-08-07
Last modified:2024-08-14
Method:SOLUTION NMR
Cite:NMR structures of small molecules bound to a model of a CUG RNA repeat expansion.
Bioorg.Med.Chem.Lett., 111, 2024
9CPI
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BU of 9cpi by Molmil
Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1
Descriptor: 4-[1-(2-aminoethyl)-4,5-dihydro-1H-imidazol-2-yl]-N-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]benzamide, RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3')
Authors:Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L.
Deposit date:2024-07-18
Release date:2024-08-07
Last modified:2024-08-14
Method:SOLUTION NMR
Cite:NMR structures of small molecules bound to a model of a CUG RNA repeat expansion.
Bioorg.Med.Chem.Lett., 111, 2024
9CPJ
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BU of 9cpj by Molmil
Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1
Descriptor: RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3')
Authors:Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L.
Deposit date:2024-07-18
Release date:2024-08-07
Method:SOLUTION NMR
Cite:Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1.
Bioorg.Med.Chem.Lett., 2024
9DLL
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BU of 9dll by Molmil
NMR structures of small molecules bound to a model of an RNA CAG repeat expansion.
Descriptor: 4-carbamimidamidophenyl 4-carbamimidamidobenzoate, CAG 13-mer RNA (5'-R(*GP*AP*CP*AP*GP*CP*AP*GP*CP*UP*GP*UP*C)-3')
Authors:Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L.
Deposit date:2024-09-11
Release date:2024-09-25
Method:SOLUTION NMR
Cite:NMR structures of small molecules bound to a model of an RNA CAG repeat expansion.
Nucleic Acids Res., 2024

225946

数据于2024-10-09公开中

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