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PDB: 5 件

8BJF
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BU of 8bjf by Molmil
Cryo-EM structure of nanodisc-reconstituted wildtype human MRP4 (inward-facing conformation)
分子名称: ATP-binding cassette sub-family C member 4, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE
著者Raj, I, Bloch, M, Pape, T.H, Taylor, N.M.I.
登録日2022-11-04
公開日2023-08-30
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural and mechanistic basis of substrate transport by the multidrug transporter MRP4.
Structure, 31, 2023
8BWO
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BU of 8bwo by Molmil
Cryo-EM structure of nanodisc-reconstituted human MRP4 with E1202Q mutation (outward-facing occluded conformation)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 4, MAGNESIUM ION
著者Raj, I, Bloch, M, Pape, T.H, Taylor, N.M.I.
登録日2022-12-07
公開日2023-08-30
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural and mechanistic basis of substrate transport by the multidrug transporter MRP4.
Structure, 31, 2023
8BWR
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BU of 8bwr by Molmil
Cryo-EM structure of nanodisc-reconstituted wildtype human MRP4 (in complex with prostaglandin E2)
分子名称: (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, ATP-binding cassette sub-family C member 4
著者Raj, I, Bloch, M, Pape, T.H, Taylor, N.M.I.
登録日2022-12-07
公開日2023-08-30
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural and mechanistic basis of substrate transport by the multidrug transporter MRP4.
Structure, 31, 2023
8BWP
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BU of 8bwp by Molmil
Cryo-EM structure of nanodisc-reconstituted wildtype human MRP4 (in complex with methotrexate)
分子名称: ATP-binding cassette sub-family C member 4, METHOTREXATE
著者Raj, I, Bloch, M, Pape, T.H, Taylor, N.M.I.
登録日2022-12-07
公開日2023-08-30
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural and mechanistic basis of substrate transport by the multidrug transporter MRP4.
Structure, 31, 2023
8BWQ
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BU of 8bwq by Molmil
Cryo-EM structure of nanodisc-reconstituted wildtype human MRP4 (in complex with topotecan)
分子名称: (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, ATP-binding cassette sub-family C member 4
著者Raj, I, Bloch, M, Pape, T.H, Taylor, N.M.I.
登録日2022-12-07
公開日2023-08-30
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural and mechanistic basis of substrate transport by the multidrug transporter MRP4.
Structure, 31, 2023

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件を2024-05-22に公開中

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