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PDB: 100 件
6C32
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Mycobacterium smegmatis RimJ with AcCoA
分子名称: ACETYL COENZYME *A, Acetyltransferase, GNAT family protein
著者Favrot, L, Hegde, S.S, Blanchard, J.S.
登録日2018-01-09
公開日2019-01-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献Structural Characterization of Mycobacterium smegmatis RimJ, an N-acetyltransferase protein
To Be Published
1M44
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Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis-APO Structure
分子名称: Aminoglycoside 2'-N-acetyltransferase, SULFATE ION
著者Vetting, M.W, Hegde, S.S, Javid-Majd, F, Blanchard, J.S, Roderick, S.L.
登録日2002-07-02
公開日2002-08-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis in complex with coenzyme A and aminoglycoside substrates.
Nat.Struct.Biol., 9, 2002
1M4D
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Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis-Complex with Coenzyme A and Tobramycin
分子名称: 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, Aminoglycoside 2'-N-acetyltransferase, COENZYME A, ...
著者Vetting, M.W, Hegde, S.S, Javid-Majd, F, Blanchard, J.S, Roderick, S.L.
登録日2002-07-02
公開日2002-08-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis in complex with coenzyme A and aminoglycoside substrates.
Nat.Struct.Biol., 9, 2002
1M4I
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Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis-Complex with Coenzyme A and Kanamycin A
分子名称: 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, Aminoglycoside 2'-N-acetyltransferase, COENZYME A, ...
著者Vetting, M.W, Hegde, S.S, Javid-Majd, F, Blanchard, J.S, Roderick, S.L.
登録日2002-07-02
公開日2002-08-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis in complex with coenzyme A and aminoglycoside substrates.
Nat.Struct.Biol., 9, 2002
2XTX
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Structure of QnrB1 (M102R-Trypsin Treated), a plasmid-mediated fluoroquinolone resistance protein
分子名称: QNRB1, SULFATE ION
著者Vetting, M.W, Hegde, S.S, Park, C.H, Jacoby, G.A, Hooper, D.C, Blanchard, J.S.
登録日2010-10-12
公開日2010-10-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Qnrb1, a Plasmid-Mediated Fluoroquinolone Resistance Factor.
J.Biol.Chem., 286, 2011
2XTW
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Structure of QnrB1 (Full length), a plasmid-mediated fluoroquinolone resistance protein
分子名称: QNRB1
著者Vetting, M.W, Hegde, S.S, Park, C.H, Jacoby, G.A, Hooper, D.C, Blanchard, J.S.
登録日2010-10-12
公開日2010-10-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献Structure of Qnrb1, a Plasmid-Mediated Fluoroquinolone Resistance Factor.
J.Biol.Chem., 286, 2011
2XTY
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Structure of QnrB1 (R167E-Trypsin Treated), a plasmid-mediated fluoroquinolone resistance protein
分子名称: QNRB1
著者Vetting, M.W, Hegde, S.S, Park, C.H, Jacoby, G.A, Hooper, D.C, Blanchard, J.S.
登録日2010-10-13
公開日2010-10-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of Qnrb1, a Plasmid-Mediated Fluoroquinolone Resistance Factor.
J.Biol.Chem., 286, 2011
2VZY
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Crystal structure of Rv0802c from Mycobacterium tuberculosis in an unliganded form.
分子名称: 2-ETHOXYETHANOL, ACETATE ION, CITRATE ANION, ...
著者Vetting, M.W, Errey, J.C, Blanchard, J.S.
登録日2008-08-07
公開日2009-04-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Rv0802C from Mycobacterium Tuberculosis: The First Structure of a Succinyltransferase with the Gnat Fold.
Acta Crystallogr.,Sect.F, 64, 2008
2VZZ
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Crystal structure of Rv0802c from Mycobacterium tuberculosis in Complex with Succinyl-CoA
分子名称: RV0802C, SUCCINYL-COENZYME A
著者Vetting, M.W, Errey, J.C, Blanchard, J.S.
登録日2008-08-07
公開日2009-04-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Rv0802C from Mycobacterium Tuberculosis: The First Structure of a Succinyltransferase with the Gnat Fold.
Acta Crystallogr.,Sect.F, 64, 2008
1DAP
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C. GLUTAMICUM DAP DEHYDROGENASE IN COMPLEX WITH NADP+
分子名称: ACETATE ION, DIAMINOPIMELIC ACID DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Scapin, G, Reddy, S.G, Blanchard, J.S.
登録日1996-07-08
公開日1997-07-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Three-dimensional structure of meso-diaminopimelic acid dehydrogenase from Corynebacterium glutamicum.
Biochemistry, 35, 1996
1ARZ
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ESCHERICHIA COLI DIHYDRODIPICOLINATE REDUCTASE IN COMPLEX WITH NADH AND 2,6 PYRIDINE DICARBOXYLATE
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIHYDRODIPICOLINATE REDUCTASE, PHOSPHATE ION, ...
著者Scapin, G, Reddy, S.G, Zheng, R, Blanchard, J.S.
登録日1997-08-08
公開日1998-10-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase in complex with NADH and the inhibitor 2,6-pyridinedicarboxylate.
Biochemistry, 36, 1997
2XT2
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Structure of the pentapeptide repeat protein AlbG, a resistance factor for the topoisomerase poison albicidin.
分子名称: MCBG-LIKE PROTEIN, SULFATE ION
著者Vetting, M.W, Hegde, S.S, Blanchard, J.S.
登録日2010-10-05
公開日2010-10-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Pentapeptide-Repeat Proteins that Act as Topoisomerase Poison Resistance Factors Have a Common Dimer Interface.
Acta Crystallogr.,Sect.F, 67, 2011
2XT4
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Structure of the pentapeptide repeat protein AlbG, a resistance factor for the topoisomerase poison albicidin.
分子名称: MCBG-LIKE PROTEIN
著者Vetting, M.W, Hegde, S.S, Blanchard, J.S.
登録日2010-10-05
公開日2010-10-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.394 Å)
主引用文献Pentapeptide-Repeat Proteins that Act as Topoisomerase Poison Resistance Factors Have a Common Dimer Interface.
Acta Crystallogr.,Sect.F, 67, 2011
2Q9J
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Crystal structure of the C217S mutant of diaminopimelate epimerase
分子名称: 1,2-ETHANEDIOL, Diaminopimelate epimerase, SULFATE ION
著者Pillai, B, Cherney, M, Diaper, C.M, Sutherland, A, Blanchard, J.S, Vederas, J.C.
登録日2007-06-12
公開日2007-10-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dynamics of catalysis revealed from the crystal structures of mutants of diaminopimelate epimerase.
Biochem.Biophys.Res.Commun., 363, 2007
2Q9H
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Crystal structure of the C73S mutant of diaminopimelate epimerase
分子名称: ACETIC ACID, Diaminopimelate epimerase, L(+)-TARTARIC ACID
著者Pillai, B, Cherney, M, Diaper, C.M, Sutherland, A, Blanchard, J.S, Vederas, J.C, James, M.N.G.
登録日2007-06-12
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Dynamics of catalysis revealed from the crystal structures of mutants of diaminopimelate epimerase.
Biochem.Biophys.Res.Commun., 363, 2007
1TDT
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THREE-DIMENSIONAL STRUCTURE OF TETRAHYDRODIPICOLINATE-N-SUCCINYLTRANSFERASE
分子名称: TETRAHYDRODIPICOLINATE-N-SUCCINYLTRANSFERASE
著者Beaman, T.W, Binder, D.W, Blanchard, J.S, Roderick, S.L.
登録日1996-11-19
公開日1997-06-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Three-dimensional structure of tetrahydrodipicolinate N-succinyltransferase.
Biochemistry, 36, 1997
1S7N
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Ribosomal L7/L12 alpha-N-protein acetyltransferase in complex with Coenzyme A (CoA free sulfhydryl)
分子名称: COENZYME A, acetyl transferase
著者Vetting, M.W, de Carvalho, L.P, Roderick, S.L, Blanchard, J.S.
登録日2004-01-29
公開日2005-03-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A novel dimeric structure of the RimL Nalpha-acetyltransferase from Salmonella typhimurium.
J.Biol.Chem., 280, 2005
1I80
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CRYSTAL STRUCTURE OF M. TUBERCULOSIS PNP IN COMPLEX WITH IMINORIBITOL, 9-DEAZAHYPOXANTHINE AND PHOSPHATE ION
分子名称: 9-DEAZAHYPOXANTHINE, IMINORIBITOL, PHOSPHATE ION, ...
著者Shi, W, Basso, L.A, Tyler, P.C, Furneaux, R.H, Blanchard, J.S, Almo, S.C, Schramm, V.L.
登録日2001-03-12
公開日2001-08-01
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces.
Biochemistry, 40, 2001
1DRV
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ESCHERICHIA COLI DHPR/ACNADH COMPLEX
分子名称: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, DIHYDRODIPICOLINATE REDUCTASE
著者Reddy, S.G, Scapin, G, Blanchard, J.S.
登録日1996-06-28
公開日1997-01-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Interaction of pyridine nucleotide substrates with Escherichia coli dihydrodipicolinate reductase: thermodynamic and structural analysis of binary complexes.
Biochemistry, 35, 1996
1DRU
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ESCHERICHIA COLI DHPR/NADH COMPLEX
分子名称: DIHYDRODIPICOLINATE REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Reddy, S.G, Scapin, G, Blanchard, J.S.
登録日1996-06-28
公開日1997-01-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Interaction of pyridine nucleotide substrates with Escherichia coli dihydrodipicolinate reductase: thermodynamic and structural analysis of binary complexes.
Biochemistry, 35, 1996
2PR2
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Structure of Mycobacterium tuberculosis enoyl-ACP reductase with bound INH-NADP.
分子名称: (4S)-ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE DINUCLEOTIDE, enoyl-ACP Reductase
著者Vetting, M.W, Argyrou, A, Blanchard, J.S.
登録日2007-05-03
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献New insight into the mechanism of action of and resistance to isoniazid: interaction of Mycobacterium tuberculosis enoyl-ACP reductase with INH-NADP
J.Am.Chem.Soc., 129, 2007
1DRW
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ESCHERICHIA COLI DHPR/NHDH COMPLEX
分子名称: DIHYDRODIPICOLINATE REDUCTASE, NICOTINAMIDE PURIN-6-OL-DINUCLEOTIDE
著者Reddy, S.G, Scapin, G, Blanchard, J.S.
登録日1996-06-28
公開日1997-01-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Interaction of pyridine nucleotide substrates with Escherichia coli dihydrodipicolinate reductase: thermodynamic and structural analysis of binary complexes.
Biochemistry, 35, 1996
1Q5N
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Crystal Structure of beta-carboxy-cis,cis-muconate cycloisomerase (CMLE) from Acinetobacter calcoaceticus sp. ADP1
分子名称: 3-carboxy-cis,cis-muconate cycloisomerase
著者Vetting, M.W, Blanchard, J.S.
登録日2003-08-08
公開日2003-08-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The lactonizing enzymes of the beta-ketoadipate pathway: The use of fundamentally different structural and mechanistic motifs to catalyze essentially identical reactions in the catabolism of aromatics
To be Published
1S7L
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RimL- Ribosomal L7/L12 alpha-N-protein acetyltransferase in complex with Coenzyme A (CoA-Cys134 Disulfide)
分子名称: COENZYME A, SULFATE ION, acetyl transferase
著者Vetting, M.W, de Carvalho, L.P, Roderick, S.L, Blanchard, J.S.
登録日2004-01-29
公開日2005-03-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A novel dimeric structure of the RimL Nalpha-acetyltransferase from Salmonella typhimurium.
J.Biol.Chem., 280, 2005
3IQA
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Crystal Structure of BlaC covalently bound with Doripenem
分子名称: (2S,3R,4S)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-4-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Beta-lactamase, PHOSPHATE ION
著者Tremblay, L.W, Blanchard, J.S.
登録日2009-08-19
公開日2010-04-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Biochemical and structural characterization of Mycobacterium tuberculosis beta-lactamase with the carbapenems ertapenem and doripenem.
Biochemistry, 49, 2010

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