7UDJ
| Crystal structure of designed helical repeat protein RPB_PEW3_R4 bound to PAWx4 peptide | Descriptor: | 4xPAW peptide, De novo designed helical repeat protein RPB_PEW3_R4 | Authors: | Redler, R.L, Chang, Y, Bhabha, G, Ekiert, D. | Deposit date: | 2022-03-20 | Release date: | 2023-03-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | De novo design of modular peptide-binding proteins by superhelical matching. Nature, 616, 2023
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7UE2
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7UPQ
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7UPO
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7UPP
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6XBD
| Cryo-EM structure of MlaFEDB in nanodiscs with phospholipid substrates | Descriptor: | DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, MSP1D1, Phospholipid ABC transporter permease protein MlaE, ... | Authors: | Coudray, N, Isom, G.L, MacRae, M.R, Saiduddin, M, Ekiert, D.C, Bhabha, G. | Deposit date: | 2020-06-05 | Release date: | 2020-07-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Structure of bacterial phospholipid transporter MlaFEDB with substrate bound. Elife, 9, 2020
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6XGZ
| Crystal structure of E. coli MlaFB ABC transport subunits in the monomeric state | Descriptor: | 1,2-ETHANEDIOL, ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ... | Authors: | Chang, Y, Bhabha, G, Ekiert, D.C. | Deposit date: | 2020-06-18 | Release date: | 2020-07-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation. Elife, 9, 2020
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6XGY
| Crystal structure of E. coli MlaFB ABC transport subunits in the dimeric state | Descriptor: | ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Chang, Y, Bhabha, G, Ekiert, D.C. | Deposit date: | 2020-06-18 | Release date: | 2020-07-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation. Elife, 9, 2020
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6XSS
| CryoEM structure of designed helical fusion protein C4_nat_HFuse-7900 | Descriptor: | C4_nat_HFuse-7900 | Authors: | Redler, R.L, Edman, N.I, Baker, D, Ekiert, D, Bhabha, G. | Deposit date: | 2020-07-16 | Release date: | 2020-12-23 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Design of multi-scale protein complexes by hierarchical building block fusion. Nat Commun, 12, 2021
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4KJK
| Room Temperature WT DHFR | Descriptor: | CALCIUM ION, Dihydrofolate reductase, FOLIC ACID, ... | Authors: | van den Bedem, H, Bhabha, G, Yang, K, Wright, P.E, Fraser, J.S. | Deposit date: | 2013-05-03 | Release date: | 2013-08-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.351 Å) | Cite: | Automated identification of functional dynamic contact networks from X-ray crystallography. Nat.Methods, 10, 2013
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4KJJ
| Cryogenic WT DHFR | Descriptor: | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | van den Bedem, H, Bhabha, G, Yang, K, Wright, P.E, Fraser, J.S. | Deposit date: | 2013-05-03 | Release date: | 2013-08-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Automated identification of functional dynamic contact networks from X-ray crystallography. Nat.Methods, 10, 2013
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4KJL
| Room Temperature N23PPS148A DHFR | Descriptor: | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | van den Bedem, H, Bhabha, G, Yang, K, Wright, P.E, Fraser, J.S. | Deposit date: | 2013-05-03 | Release date: | 2013-08-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Automated identification of functional dynamic contact networks from X-ray crystallography. Nat.Methods, 10, 2013
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6V0F
| Lipophilic Envelope-spanning Tunnel B (LetB), Model 4 | Descriptor: | Intermembrane transport protein YebT | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-11-18 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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6V0H
| Lipophilic Envelope-spanning Tunnel B (LetB), Model 6 | Descriptor: | Intermembrane transport protein YebT | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-11-18 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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6V0C
| Lipophilic Envelope-spanning Tunnel B (LetB), Model 1 | Descriptor: | Intermembrane transport protein YebT | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-11-18 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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6V0E
| Lipophilic Envelope-spanning Tunnel B (LetB), Model 3 | Descriptor: | Intermembrane transport protein YebT | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-11-18 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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6V0J
| Lipophilic Envelope-spanning Tunnel B (LetB), Model 8 | Descriptor: | Intermembrane transport protein YebT | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-11-18 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.78 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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6V0G
| Lipophilic Envelope-spanning Tunnel B (LetB), Model 5 | Descriptor: | Intermembrane transport protein YebT | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-11-18 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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6V0I
| Lipophilic Envelope-spanning Tunnel B (LetB), Model 7 | Descriptor: | Intermembrane transport protein YebT | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-11-18 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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6VCI
| Lipophilic envelope-spanning tunnel protein (LetB), domains MCE2-MCE3 | Descriptor: | Lipophilic envelope-spanning tunnel protein LetB | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-12-21 | Release date: | 2020-05-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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6V0D
| Lipophilic Envelope-spanning Tunnel B (LetB), Model 2 | Descriptor: | Intermembrane transport protein YebT | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | Deposit date: | 2019-11-18 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell, 181, 2020
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