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PDB: 20 件

3T4B
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Crystal Structure of the HCV IRES pseudoknot domain
分子名称: HCV IRES pseudoknot domain plus crystallization module, NICKEL (II) ION
著者Berry, K.E, Waghray, S, Mortimer, S.A, Bai, Y, Doudna, J.A.
登録日2011-07-25
公開日2011-10-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.55 Å)
主引用文献Crystal structure of the HCV IRES central domain reveals strategy for start-codon positioning.
Structure, 19, 2011
1LI7
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BU of 1li7 by Molmil
Crystal Structure of Cysteinyl-tRNA Synthetase with Cysteine Substrate Bound
分子名称: CYSTEINE, CYSTEINYL-TRNA SYNTHETASE, ZINC ION
著者Newberry, K.J, Hou, Y.-M, Perona, J.J.
登録日2002-04-17
公開日2002-04-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase
EMBO J., 21, 2002
1LI5
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Crystal Structure of Cysteinyl-tRNA Synthetase
分子名称: CYSTEINYL-TRNA SYNTHETASE, ZINC ION
著者Newberry, K.J, Hou, Y.-M, Perona, J.J.
登録日2002-04-17
公開日2002-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase
EMBO J., 21, 2002
3D71
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Crystal structure of E253Q BMRR bound to 22 base pair promoter site
分子名称: BMR promoter DNA, CITRATE ANION, IMIDAZOLE, ...
著者Newberry, K.J, Huffman, J.L, Brennan, R.G.
登録日2008-05-20
公開日2008-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of BmrR-Drug Complexes Reveal a Rigid Multidrug Binding Pocket and Transcription Activation through Tyrosine Expulsion
J.Biol.Chem., 283, 2008
3D70
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Crystal structure of E253A mutant of BMRR bound to 22-bp oligonucleotide
分子名称: BMR promoter DNA, GLYCEROL, IMIDAZOLE, ...
著者Newberry, K.J, Brennan, R.G.
登録日2008-05-20
公開日2008-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of BmrR-Drug Complexes Reveal a Rigid Multidrug Binding Pocket and Transcription Activation through Tyrosine Expulsion
J.Biol.Chem., 283, 2008
3D6Z
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Crystal structure of R275E mutant of BMRR bound to DNA and rhodamine
分子名称: BMR promoter DNA, GLYCEROL, Multidrug-efflux transporter 1 regulator, ...
著者Newberry, K.J, Brennan, R.G.
登録日2008-05-20
公開日2008-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of BmrR-Drug Complexes Reveal a Rigid Multidrug Binding Pocket and Transcription Activation through Tyrosine Expulsion
J.Biol.Chem., 283, 2008
3D6Y
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Crystal structure of R275E mutant of BMRR bound to DNA and berberine
分子名称: BERBERINE, BMR promoter DNA, GLYCEROL, ...
著者Newberry, K.J, Brennan, R.G.
登録日2008-05-20
公開日2008-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of BmrR-Drug Complexes Reveal a Rigid Multidrug Binding Pocket and Transcription Activation through Tyrosine Expulsion
J.Biol.Chem., 283, 2008
1R8E
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Crystal Structure of BmrR Bound to DNA at 2.4A Resolution
分子名称: 5'-D(*GP*AP*CP*CP*CP*TP*CP*CP*CP*CP*TP*TP*AP*GP*GP*GP*GP*AP*GP*GP*GP*TP*C)-3', GLYCEROL, IMIDAZOLE, ...
著者Newberry, K.J, Brennan, R.G.
登録日2003-10-23
公開日2004-08-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus.
J.Biol.Chem., 279, 2004
3IHQ
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BU of 3ihq by Molmil
Crystal Structure of Reduced C10S Spx in Complex with the Alpha C-terminal Domain of RNA Polymeras
分子名称: DNA-directed RNA polymerase subunit alpha, IMIDAZOLE, Regulatory protein spx
著者Newberry, K.J, Brennan, R.G.
登録日2009-07-30
公開日2010-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Promoter recognition by a complex of Spx and the C-terminal domain of the RNA polymerase alpha subunit.
Plos One, 5, 2010
1R8D
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Crystal Structure of MtaN Bound to DNA
分子名称: 26-MER, SULFATE ION, transcription activator MtaN
著者Newberry, K.J, Brennan, R.G.
登録日2003-10-23
公開日2004-08-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus.
J.Biol.Chem., 279, 2004
1Z3E
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Crystal Structure of Spx in Complex with the C-terminal Domain of the RNA Polymerase Alpha Subunit
分子名称: DNA-directed RNA polymerase alpha chain, Regulatory protein spx, SULFATE ION
著者Newberry, K.J, Nakano, S, Zuber, P, Brennan, R.G.
登録日2005-03-11
公開日2005-10-11
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the Bacillus subtilis anti-alpha, global transcriptional regulator, Spx, in complex with the {alpha} C-terminal domain of RNA polymerase
Proc.Natl.Acad.Sci.Usa, 102, 2005
6PYO
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BU of 6pyo by Molmil
Calcium Activated Chloride Channel Regulator 1 (CLCA1) VWA Domain
分子名称: CALCIUM ION, cDNA FLJ56608, highly similar to Homo sapiens chloride channel, ...
著者Brett, T.J, Berry, K.B.
登録日2019-07-30
公開日2020-01-29
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Biophysical Analysis of the CLCA1 VWA Domain Suggests Mode of TMEM16A Engagement.
Cell Rep, 30, 2020
6PYX
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BU of 6pyx by Molmil
Calcium Activated Chloride Channel Regulator 1 (CLCA1) VWA Domain
分子名称: CALCIUM ION, cDNA FLJ56608, highly similar to Homo sapiens chloride channel, ...
著者Brett, T.J, Berry, K.B.
登録日2019-07-31
公開日2020-01-29
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and Biophysical Analysis of the CLCA1 VWA Domain Suggests Mode of TMEM16A Engagement.
Cell Rep, 30, 2020
4J1R
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BU of 4j1r by Molmil
Crystal Structure of GSK3b in complex with inhibitor 15R
分子名称: (2R)-2-(1H-indol-3-ylmethyl)-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one, Glycogen synthase kinase-3 beta, PHOSPHATE ION, ...
著者Zhan, C, Wang, Y, Wach, J, Sheehan, P, Zhong, C, Harris, R, Patskovsky, Y, Bishop, J, Haggarty, S, Ramek, A, Berry, K, O'Herin, C, Koehler, A.N, Hung, A.W, Young, D.W, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2013-02-01
公開日2013-03-20
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Fragment-based approach using diversity-oriented synthesis yields a GSK3b inhibitor
To be Published
4J71
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Crystal Structure of GSK3b in complex with inhibitor 1R
分子名称: (2R)-2-methyl-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one, CHLORIDE ION, Glycogen synthase kinase-3 beta, ...
著者Zhan, C, Wang, Y, Wach, J, Sheehan, P, Zhong, C, Harris, R, Patskovsky, Y, Bishop, J, Haggarty, S, Ramek, A, Berry, K, O'Herin, C, Koehler, A.N, Hung, A.W, Young, D.W, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2013-02-12
公開日2013-03-20
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Fragment-based approach using diversity-oriented synthesis yields a GSK3b inhibitor
To be Published
2PEX
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BU of 2pex by Molmil
Structure of reduced C22S OhrR from Xanthamonas Campestris
分子名称: FORMIC ACID, Transcriptional regulator OhrR
著者Brennan, R.G, Newberry, K.J.
登録日2007-04-03
公開日2007-12-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Mechanism of Organic Hydroperoxide Induction of the Transcription Regulator OhrR.
Mol.Cell, 28, 2007
2PFB
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BU of 2pfb by Molmil
Structure of oxidized OhrR from Xanthamonas campestris
分子名称: Transcriptional regulator OhrR
著者Brennan, R.G, Newberry, K.J.
登録日2007-04-04
公開日2007-12-11
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural Mechanism of Organic Hydroperoxide Induction of the Transcription Regulator OhrR.
Mol.Cell, 28, 2007
1EUY
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BU of 1euy by Molmil
GLUTAMINYL-TRNA SYNTHETASE COMPLEXED WITH A TRNA MUTANT AND AN ACTIVE SITE INHIBITOR
分子名称: 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE, GLUTAMINYL TRNA, GLUTAMINYL-TRNA SYNTHETASE
著者Sherlin, L.D, Bullock, T.L, Newberry, K.J, Lipman, R.S.A, Hou, Y.-M, Beijer, B, Sproat, B.S, Perona, J.J.
登録日2000-04-19
公開日2000-06-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Influence of transfer RNA tertiary structure on aminoacylation efficiency by glutaminyl and cysteinyl-tRNA synthetases.
J.Mol.Biol., 299, 2000
1EUQ
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BU of 1euq by Molmil
CRYSTAL STRUCTURE OF GLUTAMINYL-TRNA SYNTHETASE COMPLEXED WITH A TRNA-GLN MUTANT AND AN ACTIVE-SITE INHIBITOR
分子名称: 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE, GLUTAMINYL TRNA, GLUTAMINYL-TRNA SYNTHETASE
著者Sherlin, L.D, Bullock, T.L, Newberry, K.J, Lipman, R.S.A, Hou, Y.-M, Beijer, B, Sproat, B.S, Perona, J.J.
登録日2000-04-17
公開日2000-06-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Influence of transfer RNA tertiary structure on aminoacylation efficiency by glutaminyl and cysteinyl-tRNA synthetases.
J.Mol.Biol., 299, 2000
3IAO
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BU of 3iao by Molmil
Conformational plasticity of the coiled coil domain of BmrR is required for bmr promoter binding-the unliganded structure of BmrR
分子名称: Multidrug-efflux transporter 1 regulator
著者Kumaraswami, M, Newberry, K.J, Brennan, R.G.
登録日2009-07-14
公開日2010-04-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformational plasticity of the coiled-coil domain of BmrR is required for bmr operator binding: the structure of unliganded BmrR.
J.Mol.Biol., 398, 2010

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