4IBM
| Crystal structure of insulin receptor kinase domain in complex with an inhibitor Irfin-1 | 分子名称: | 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-3H-pyrazolo[3,4-c]pyridazin-3-one, Insulin receptor | 著者 | Wu, J, Anastassiadis, T, Duong-Ly, K.C, Peterson, J.R. | 登録日 | 2012-12-08 | 公開日 | 2013-08-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an extracellular signal-regulated kinase (ERK) inhibitor. J.Biol.Chem., 288, 2013
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