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PDB: 55 件

1B6P
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HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 7
分子名称: N-[3-(8-SEC-BUTYL-7,10-DIOXO-2-OXA-6,9-DIAZA-BICYCLO[11.2.2] HEPTADECA-1(16),13(17),14-TRIEN-11-YAMINO)-2-HYDROXY-1-(4-HYDROXY-BENZYL) -PROPYL]-3-METHYL-2-PROPIONYLAMINO-BUTYRAMIDE, RETROPEPSIN, SULFATE ION
著者Martin, J.L, Begun, J, Schindeler, A, Wickramasinghe, W.A, Alewood, D, Alewood, P.F, Bergman, D.A, Brinkworth, R.I, Abbenante, G, March, D.R, Reid, R.C, Fairlie, D.P.
登録日1999-01-17
公開日2000-01-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.
Biochemistry, 38, 1999
1B6M
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HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 6
分子名称: RETROPEPSIN, SULFATE ION, [1-BENZYL-3-(8-SEC-BUTYL-7,10-DIOXO-2-OXA-6,9-DIAZA-BICYCLO[11.2.2] HEPTADECA-1(16),13(17),14-TRIEN-11-YLAMINO)-2-HYDROXY-PROPYL]-CARBAMIC ACID TERT-BUTYL ESTER
著者Martin, J.L, Begun, J, Schindeler, A, Wickramasinghe, W.A, Alewood, D, Alewood, P.F, Bergman, D.A, Brinkworth, R.I, Abbenante, G, March, D.R, Reid, R.C, Fairlie, D.P.
登録日1999-01-17
公開日2000-01-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.
Biochemistry, 38, 1999
1B6J
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HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 1
分子名称: CYCLIC PEPTIDE INHIBITOR, RETROPEPSIN, SULFATE ION
著者Martin, J.L, Begun, J, Schindeler, A, Wickramasinghe, W.A, Alewood, D, Alewood, P.F, Bergman, D.A, Brinkworth, R.I, Abbenante, G, March, D.R, Reid, R.C, Fairlie, D.P.
登録日1999-01-17
公開日2000-01-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.
Biochemistry, 38, 1999
1B6L
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HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 4
分子名称: 1-[2-(8-CARBAMOYLMETHYL-6,9-DIOXO-2-OXA-7,10-DIAZA-BICYCLO[11.2.2]HEPTADECA- 1(16),13(17),14-TRIEN-11-YL)-2-HYDROXY-ETHYL]-PIPERIDINE-2-CARBOXYLIC ACID TERT-BUTYLAMIDE, RETROPEPSIN, SULFATE ION
著者Martin, J.L, Begun, J, Schindeler, A, Wickramasinghe, W.A, Alewood, D, Alewood, P.F, Bergman, D.A, Brinkworth, R.I, Abbenante, G, March, D.R, Reid, R.C, Fairlie, D.P.
登録日1999-01-17
公開日2000-01-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.
Biochemistry, 38, 1999
1B8W
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DEFENSIN-LIKE PEPTIDE 1
分子名称: PROTEIN (DEFENSIN-LIKE PEPTIDE 1)
著者Torres, A.M, Wang, X, Fletcher, J.I, Alewood, D, Alewood, P.F, Smith, R, Simpson, R.J, Nicholson, G.M, Sutherland, S.K, Gallagher, C.H, King, G.F, Kuchel, P.W.
登録日1999-02-02
公開日1999-09-15
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of a defensin-like peptide from platypus venom.
Biochem.J., 341, 1999
1ZUF
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Solution Structure of DLP-4
分子名称: Defensin-like peptide 2/4
著者Torres, A.M, Tsampazi, C, Geraghty, D.P, Bansal, P.S, Alewood, P.F, Kuchel, P.W.
登録日2005-05-31
公開日2005-08-02
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献D-amino acid residue in a defensin-like peptide from platypus venom: effect on structure and chromatographic properties.
Biochem.J., 391, 2005
1ZUE
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Revised Solution Structure of DLP-2
分子名称: Defensin-like peptide 2/4
著者Torres, A.M, Tsampazi, C, Geraghty, D.P, Bansal, P.S, Alewood, P.F, Kuchel, P.W.
登録日2005-05-30
公開日2005-08-02
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献D-amino acid residue in a defensin-like peptide from platypus venom: effect on structure and chromatographic properties.
Biochem.J., 391, 2005
1IEN
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SOLUTION STRUCTURE OF TIA
分子名称: PROTEIN TIA
著者Sharpe, I.A, Gehrmann, J, Loughnan, M.L, Thomas, L, Adams, D.A, Atkins, A, Palant, E, Craik, D.J, Adams, D.J, Alewood, P.F, Lewis, R.J.
登録日2001-04-10
公開日2002-04-03
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter.
Nat.Neurosci., 4, 2001
1GIB
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MU-CONOTOXIN GIIIB, NMR
分子名称: MU-CONOTOXIN GIIIB
著者Hill, J.M, Alewood, P.F, Craik, D.J.
登録日1996-04-17
公開日1996-11-08
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Three-dimensional solution structure of mu-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels.
Biochemistry, 35, 1996
1IEO
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SOLUTION STRUCTURE OF MRIB-NH2
分子名称: PROTEIN MRIB-NH2
著者Sharpe, I.A, Gehrmann, J, Loughnan, M.L, Thomas, L, Adams, D.A, Atkins, A, Palant, E, Craik, D.J, Adams, D.J, Alewood, P.F, Lewis, R.J.
登録日2001-04-10
公開日2002-04-03
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter.
Nat.Neurosci., 4, 2001
1PEN
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ALPHA-CONOTOXIN PNI1
分子名称: ALPHA-CONOTOXIN PNIA
著者Hu, S.-H, Gehrmann, J, Guddat, L.W, Alewood, P.F, Craik, D.J, Martin, J.L.
登録日1996-01-29
公開日1997-04-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献The 1.1 A crystal structure of the neuronal acetylcholine receptor antagonist, alpha-conotoxin PnIA from Conus pennaceus.
Structure, 4, 1996
1R9I
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NMR Solution Structure of PIIIA toxin, NMR, 20 structures
分子名称: Mu-conotoxin PIIIA
著者Nielsen, K.J, Watson, M, Adams, D.J, Hammarstrom, A.K, Gage, P.W, Hill, J.M, Craik, D.J, Thomas, L, Adams, D, Alewood, P.F, Lewis, R.J.
登録日2003-10-30
公開日2003-11-18
最終更新日2019-12-25
実験手法SOLUTION NMR
主引用文献Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels
J.Biol.Chem., 277, 2002
1KQH
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NMR Solution Structure of the cis Pro30 Isomer of ACTX-Hi:OB4219
分子名称: ACTX-Hi:OB4219
著者Rosengren, K.J, Wilson, D, Daly, N.L, Alewood, P.F, Craik, D.J.
登録日2002-01-05
公開日2002-02-06
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structures of the cis- and trans-Pro30 isomers of a novel 38-residue toxin from the venom of Hadronyche Infensa sp. that contains a cystine-knot motif within its four disulfide bonds
Biochemistry, 41, 2002
1KQI
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NMR Solution Structure of the trans Pro30 Isomer of ACTX-Hi:OB4219
分子名称: ACTX-Hi:OB4219
著者Rosengren, K.J, Wilson, D, Daly, N.L, Alewood, P.F, Craik, D.J.
登録日2002-01-06
公開日2002-02-06
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structures of the cis- and trans-Pro30 isomers of a novel 38-residue toxin from the venom of Hadronyche Infensa sp. that contains a cystine-knot motif within its four disulfide bonds
Biochemistry, 41, 2002
2KYJ
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Structure of the scorpion toxin U1-Liotoxin-Lw1a
分子名称: LITX
著者Smith, J, Hill, J, Alewood, P.F, King, G.F.
登録日2010-05-28
公開日2011-06-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure of the scorpion toxin U1-Liotoxin-Lw1a
To be Published
1MVI
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N-TYPE CALCIUM CHANNEL BLOCKER, OMEGA-CONOTOXIN MVIIA, NMR, 15 STRUCTURES
分子名称: MVIIA
著者Nielsen, K.J, Thomas, L, Lewis, R.J, Alewood, P.F, Craik, D.J.
登録日1996-08-02
公開日1997-08-12
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202.
J.Mol.Biol., 263, 1996
1MVJ
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N-TYPE CALCIUM CHANNEL BLOCKER, OMEGA-CONOTOXIN MVIIA NMR, 15 STRUCTURES
分子名称: SVIB
著者Nielsen, K.J, Thomas, L, Lewis, R.J, Alewood, P.F, Craik, D.J.
登録日1996-08-02
公開日1997-08-12
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202.
J.Mol.Biol., 263, 1996
1MTQ
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THREE-DIMENSIONAL SOLUTION STRUCTURE OF ALPHA-CONOTOXIN GID BY NMR SPECTROSCOPY
分子名称: alpha-conotoxin GID
著者Nicke, A, Loughnan, M.L, Millard, E.L, Alewood, P.F, Adams, D.J, Daly, N.L, Craik, D.J, Lewis, R.J.
登録日2002-09-22
公開日2003-02-11
最終更新日2020-06-24
実験手法SOLUTION NMR
主引用文献Isolation, Structure, and Activity of GID, a Novel alpha 4/7-Conotoxin with an Extended N-terminal Sequence
J.BIOL.CHEM., 278, 2003
1ONU
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NMDA RECEPTOR ANTAGONIST, CONANTOKIN-G, NMR, 17 STRUCTURES
分子名称: CONANTOKIN-G
著者Skjaerbaek, N, Nielsen, K.J, Lewis, R.J, Alewood, P.F, Craik, D.J.
登録日1996-08-27
公開日1997-09-04
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Determination of the solution structures of conantokin-G and conantokin-T by CD and NMR spectroscopy.
J.Biol.Chem., 272, 1997
2JM2
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Structure of the N-terminal subdomain of insulin-like growth factor (IGF) binding protein-6 and its interactions with IGFs
分子名称: Insulin-like growth factor-binding protein 6
著者Chandrashekaran, I.R, Yao, S, Wang, C.C, Bansal, P.S, Alewood, P.F, Forbes, B.E, Wallace, J.C, Bach, L.A, Norton, R.S.
登録日2006-09-18
公開日2007-03-27
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献The N-Terminal Subdomain of Insulin-like Growth Factor (IGF) Binding Protein 6. Structure and Interaction with IGFs
Biochemistry, 46, 2007
1MII
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SOLUTION STRUCTURE OF ALPHA-CONOTOXIN MII
分子名称: PROTEIN (ALPHA CONOTOXIN MII)
著者Hill, J.M, Oomen, C.J, Miranda, L.P, Bingham, J.P, Alewood, P.F, Craik, D.J.
登録日1998-10-05
公開日1998-10-21
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Three-dimensional solution structure of alpha-conotoxin MII by NMR spectroscopy: effects of solution environment on helicity.
Biochemistry, 37, 1998
1MXN
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Solution structure of alpha-conotoxin AuIB
分子名称: alpha-conotoxin AuIB
著者Dutton, J.L, Bansal, P.S, Hogg, R.C, Adams, D.J, Alewood, P.F, Craik, D.J.
登録日2002-10-02
公開日2002-12-30
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献A New Level of Conotoxin Diversity, a Non-native Disulfide Bond Connectivity in alpha -Conotoxin AuIB Reduces Structural Definition but Increases Biological Activity.
J.Biol.Chem., 277, 2002
1MXP
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Solution structure of the ribbon disulfide bond isomer of alpha-conotoxin AuIB
分子名称: alpha-conotoxin AuIB
著者Dutton, J.L, Bansal, P.S, Hogg, R.C, Adams, D.J, Alewood, P.F, Craik, D.J.
登録日2002-10-03
公開日2002-12-30
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献A New Level of Conotoxin Diversity, a Non-native Disulfide Bond Connectivity in alpha -Conotoxin AuIB Reduces Structural Definition but Increases Biological Activity.
J.Biol.Chem., 277, 2002
1ONT
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NMDA RECEPTOR ANTAGONIST, CONANTOKIN-T, NMR, 17 STRUCTURES
分子名称: CONANTOKIN-T
著者Skjaerbaek, N, Nielsen, K.J, Lewis, R.J, Alewood, P.F, Craik, D.J.
登録日1996-08-27
公開日1997-09-04
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Determination of the solution structures of conantokin-G and conantokin-T by CD and NMR spectroscopy.
J.Biol.Chem., 272, 1997
2NS3
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Solution structure of ribbon BuIA
分子名称: Alpha-conotoxin BuIA
著者Jin, A.H, Brandstaetter, H, Nevin, S.T, Tan, C.C, Clark, R.J, Adams, D.J, Alewood, P.F, Craik, D.J, Daly, N.L.
登録日2006-11-03
公開日2007-09-25
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of alpha-conotoxin BuIA: influences of disulfide connectivity on structural dynamics
Bmc Struct.Biol., 7, 2007

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