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BRAF in complex with N-(3-(2-(2-hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide (LXH254)
Descriptor:	N-{3-[2-(2-hydroxyethoxy)-6-(morpholin-4-yl)pyridin-4-yl]-4-methylphenyl}-2-(trifluoromethyl)pyridine-4-carboxamide, Serine/threonine-protein kinase B-raf
Authors:	Mamo, M, Appleton, B.A.
Deposit date:	2018-11-07
Release date:	2019-09-04
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (2.37 Å)
Cite:	Design and Discovery ofN-(3-(2-(2-Hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide, a Selective, Efficacious, and Well-Tolerated RAF Inhibitor Targeting RAS Mutant Cancers: The Path to the Clinic. J.Med.Chem., 63, 2020

Designed repeat protein in complex with Fz8
Descriptor:	(4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ACETIC ACID, ...
Authors:	Miao, Y, Jude, K.M, Garcia, K.C.
Deposit date:	2018-12-14
Release date:	2019-05-15
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.264 Å)
Cite:	Receptor subtype discrimination using extensive shape complementary designed interfaces. Nat.Struct.Mol.Biol., 26, 2019

Crystal Structure of pks13-ACP domain from Corynebacterium diphtheriae
Descriptor:	4'-PHOSPHOPANTETHEINE, Polyketide synthase involved in mycolic acid biosynthesis
Authors:	Liu, X.
Deposit date:	2022-01-27
Release date:	2022-02-23
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (1.794 Å)
Cite:	Crystal structures of FadD32 and pks13-ACP domain from Corynebacterium diphtheriae. Biochem.Biophys.Res.Commun., 590, 2022

Crystal structures of FadD32 from Corynebacterium diphtheriae
Descriptor:	Acyl-CoA synthase, MAGNESIUM ION, MYRISTIC ACID, ...
Authors:	Liu, X.
Deposit date:	2022-02-07
Release date:	2022-08-10
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (1.999 Å)
Cite:	Crystal structures of FadD32 and pks13-ACP domain from Corynebacterium diphtheriae Biochem Biophys Res Commun, 590, 2022