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Crystal structure of the CysR-CTLD3 fragment of human DEC205
Descriptor:	Lymphocyte antigen 75
Authors:	Qian, Y, Kong, D, Yu, B, He, Y.
Deposit date:	2023-07-29
Release date:	2024-02-28
Last modified:	2024-03-20
Method:	X-RAY DIFFRACTION (2.79 Å)
Cite:	Interaction of human dendritic cell receptor DEC205/CD205 with keratins. J.Biol.Chem., 300, 2024

The crystal structure of TrkA kinase in complex with 4^6,14-dimethyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-10-oxo-5-oxa-11,14-diaza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclo- tetradecaphan-2-yne-45-carboxamide
Descriptor:	4^6,14-dimethyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-10-oxo-5-oxa-11,14-diaza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclo-tetradecaphan-2-yne-45-carboxamide, High affinity nerve growth factor receptor
Authors:	Zhang, Z.M, Wang, Y.J.
Deposit date:	2022-03-17
Release date:	2022-06-01
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (3.001182 Å)
Cite:	Discovery of the First Highly Selective and Broadly Effective Macrocycle-Based Type II TRK Inhibitors that Overcome Clinically Acquired Resistance. J.Med.Chem., 65, 2022