5OBM
| Crystal structure of Gentamicin bound to the yeast 80S ribosome | 分子名称: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDROXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. | 登録日 | 2017-06-28 | 公開日 | 2017-12-13 | 最終更新日 | 2017-12-27 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1EI1
| DIMERIZATION OF E. COLI DNA GYRASE B PROVIDES A STRUCTURAL MECHANISM FOR ACTIVATING THE ATPASE CATALYTIC CENTER | 分子名称: | DNA GYRASE B, GLYCEROL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Brino, L, Urzhumtsev, A, Oudet, P, Moras, D. | 登録日 | 2000-02-23 | 公開日 | 2000-03-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Dimerization of Escherichia coli DNA-gyrase B provides a structural mechanism for activating the ATPase catalytic center. J.Biol.Chem., 275, 2000
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2FQN
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2G5K
| Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site complexed with Apramycin | 分子名称: | 5'-R(*UP*UP*GP*CP*GP*UP*CP*GP*CP*UP*CP*CP*GP*GP*AP*AP*AP*AP*GP*UP*CP*GP*C)-3', APRAMYCIN, COBALT HEXAMMINE(III), ... | 著者 | Kondo, J, Francois, B, Urzhumtsev, A, Westhof, E. | 登録日 | 2006-02-23 | 公開日 | 2006-06-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site Complexed with Apramycin Angew.Chem.Int.Ed.Engl., 45, 2006
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4B3X
| Bacterial translation initiation factor IF2 (1-363), apo form | 分子名称: | GLYCEROL, TRANSLATION INITIATION FACTOR IF-2 | 著者 | Simonetti, A, Urzhumtsev, A, Klaholz, B.P. | 登録日 | 2012-07-26 | 公開日 | 2013-05-29 | 最終更新日 | 2013-06-05 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure of the Protein Core of Translation Initiation Factor 2 in Apo, GTP-Bound and Gdp-Bound Forms Acta Crystallogr.,Sect.D, 69, 2013
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4B43
| Bacterial translation initiation factor IF2 (1-363), apo form, double mutant K86L H130A | 分子名称: | GLYCEROL, IODIDE ION, MAGNESIUM ION, ... | 著者 | Simonetti, A, Urzhumtsev, A, Klaholz, B.P. | 登録日 | 2012-07-27 | 公開日 | 2013-09-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.937 Å) | 主引用文献 | Molecular Basis of GTP Hydrolysis by Bacterial Translation Initiation Factor If2 To be Published
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4B44
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4B47
| Bacterial translation initiation factor IF2 (1-363), complex with GDP at pH6.5 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, TRANSLATION INITIATION FACTOR IF-2 | 著者 | Simonetti, A, Urzhumtsev, A, Klaholz, B.P. | 登録日 | 2012-07-27 | 公開日 | 2013-05-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Structure of the Protein Core of Translation Initiation Factor 2 in Apo, GTP-Bound and Gdp-Bound Forms Acta Crystallogr.,Sect.D, 69, 2013
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4B48
| Bacterial translation initiation factor IF2 (1-363), complex with GTP | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, TRANSLATION INITIATION FACTOR IF-2 | 著者 | Simonetti, A, Urzhumtsev, A, Klaholz, B.P. | 登録日 | 2012-07-27 | 公開日 | 2013-05-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of the Protein Core of Translation Initiation Factor 2 in Apo, GTP-Bound and Gdp-Bound Forms Acta Crystallogr.,Sect.D, 69, 2013
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5NDJ
| Crystal structure of aminoglycoside TC007 in complex with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA (soaking) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. | 登録日 | 2017-03-08 | 公開日 | 2018-05-02 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5NDK
| Crystal structure of aminoglycoside TC007 co-crystallized with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. | 登録日 | 2017-03-08 | 公開日 | 2017-12-13 | 最終更新日 | 2017-12-27 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5NDG
| Crystal structure of geneticin (G418) bound to the yeast 80S ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. | 登録日 | 2017-03-08 | 公開日 | 2017-12-13 | 最終更新日 | 2018-04-25 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5NDW
| Crystal structure of aminoglycoside TC007 bound to the yeast 80S ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. | 登録日 | 2017-03-09 | 公開日 | 2017-12-13 | 最終更新日 | 2017-12-27 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5NDV
| Crystal structure of Paromomycin bound to the yeast 80S ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. | 登録日 | 2017-03-09 | 公開日 | 2017-12-13 | 最終更新日 | 2017-12-27 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1AH4
| PIG ALDOSE REDUCTASE, HOLO FORM | 分子名称: | ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Moras, D, Podjarny, A. | 登録日 | 1997-04-12 | 公開日 | 1998-04-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil. Structure, 5, 1997
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1AH3
| ALDOSE REDUCTASE COMPLEXED WITH TOLRESTAT INHIBITOR | 分子名称: | ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TOLRESTAT | 著者 | Moras, D, Podjarny, A. | 登録日 | 1997-04-12 | 公開日 | 1998-04-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil. Structure, 5, 1997
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1AH0
| PIG ALDOSE REDUCTASE COMPLEXED WITH SORBINIL | 分子名称: | ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SORBINIL | 著者 | Moras, D, Podjarny, A.D. | 登録日 | 1997-04-11 | 公開日 | 1998-04-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil. Structure, 5, 1997
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1ELP
| GAMMA-D CRYSTALLIN STRUCTURE AT 1.95 A RESOLUTION | 分子名称: | GAMMA-D CRYSTALLIN | 著者 | Chirgadze, Yu.N, Driessen, H.P.C, Wright, G, Slingsby, C, Hay, R.E, Lindley, P.F. | 登録日 | 1995-12-20 | 公開日 | 1996-06-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure of bovine eye lens gammaD (gammaIIIb)-crystallin at 1.95 A. Acta Crystallogr.,Sect.D, 52, 1996
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1H4A
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7BBM
| Mutant nitrobindin M75L/H76L/Q96C/M148L (NB4H) from Arabidopsis thaliana with cofactor MnPPIX | 分子名称: | 1,2-ETHANEDIOL, MANGANESE PROTOPORPHYRIN IX, UPF0678 fatty acid-binding protein-like protein At1g79260 | 著者 | Minges, A, Sauer, D.F, Wittwer, M, Markel, U, Spiertz, M, Schiffels, J, Davari, M.D, Okuda, J, Schwaneberg, U, Groth, G. | 登録日 | 2020-12-18 | 公開日 | 2021-05-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | Chemogenetic engineering of nitrobindin toward an artificial epoxygenase Catalysis Science And Technology, 2021
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8RUU
| Fabs derived from bimekizumab in complex with IL-17F | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoblobulin heavy chain, Immunoblobulin light chain, ... | 著者 | Adams, R, Lawson, A.D.G. | 登録日 | 2024-01-31 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Crystal Structure of Bimekizumab Fab Fragment in Complex with IL-17F Provides Molecular Basis for Dual IL-17A and IL-17F Inhibition J Invest Dermatol., 2024
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3B43
| I-band fragment I65-I70 from titin | 分子名称: | Titin | 著者 | von Castelmur, E, Marino, M, Labeit, D, Labeit, S, Mayans, O. | 登録日 | 2007-10-23 | 公開日 | 2008-01-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | A regular pattern of Ig super-motifs defines segmental flexibility as the elastic mechanism of the titin chain Proc.Natl.Acad.Sci.Usa, 105, 2008
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6QIX
| The crystal structure of Trichuris muris p43 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | 著者 | Levy, C.W. | 登録日 | 2019-01-21 | 公開日 | 2019-06-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | The major secreted protein of the whipworm parasite tethers to matrix and inhibits interleukin-13 function. Nat Commun, 10, 2019
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7LM4
| The crystal structure of the I38T mutant PA Endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988503 | 分子名称: | 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-2-(2-methylphenyl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... | 著者 | Cuypers, M.G, Slavish, P.J, Jayaraman, S, Rankovic, Z, White, S.W. | 登録日 | 2021-02-05 | 公開日 | 2022-02-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential. Eur.J.Med.Chem., 247, 2023
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8BHD
| N-terminal domain of Plasmodium berghei glutamyl-tRNA synthetase (Tbxo4 derivative crystal structure) | 分子名称: | GLYCEROL, Glutamate--tRNA ligase, SULFATE ION, ... | 著者 | Benas, P, Jaramillo Ponce, J.R, Legrand, P, Frugier, M, Sauter, C. | 登録日 | 2022-10-31 | 公開日 | 2023-01-25 | 最終更新日 | 2023-02-08 | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | 主引用文献 | Solution X-ray scattering highlights discrepancies in Plasmodium multi-aminoacyl-tRNA synthetase complexes. Protein Sci., 32, 2023
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