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2OP3
The structure of cathepsin S with a novel 2-arylphenoxyacetaldehyde inhibitor derived by the Substrate Activity Screening (SAS) method
Descriptor:
2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, 2-[(2',3',4'-TRIFLUOROBIPHENYL-2-YL)OXY]ETHANOL, Cathepsin S, ...
Authors:
Spraggon, G
,
Inagaki, H
,
Tsuruoka, H
,
Hornsby, M
,
Lesley, S.A
,
Ellman, J.A.
Deposit date:
2007-01-26
Release date:
2007-05-22
Last modified:
2023-08-30
Method:
X-RAY DIFFRACTION (1.6 Å)
Cite:
Characterization and optimization of selective, nonpeptidic inhibitors of cathepsin S with an unprecedented binding mode.
J.Med.Chem., 50, 2007
6L88
Crystal structure of mineralocorticoid receptor ligand binding domain in complex with esaxerenone
Descriptor:
1-(2-hydroxyethyl)-4-methyl-N-(4-methylsulfonylphenyl)-5-[2-(trifluoromethyl)phenyl]pyrrole-3-carboxamide, Mineralocorticoid receptor
Authors:
Takahashi, M
,
Hanzawa, H.
Deposit date:
2019-11-05
Release date:
2020-02-12
Last modified:
2023-11-22
Method:
X-RAY DIFFRACTION (3 Å)
Cite:
Crystal structure of the mineralocorticoid receptor ligand-binding domain in complex with a potent and selective nonsteroidal blocker, esaxerenone (CS-3150).
Febs Lett., 594, 2020
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건을2024-04-24부터공개중