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BRD4 first bromodomain (BD1) in complex with dual PI3 kinase (PI3K) inhibitor SF2558HA
Descriptor:	Bromodomain-containing protein 4, N-hydroxy-4-[5-(morpholin-4-yl)-7-oxo-7H-thieno[3,2-b]pyran-3-yl]benzamide
Authors:	Andrews, F.H, Kutateladze, T.G.
Deposit date:	2016-11-30
Release date:	2017-02-08
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.525 Å)
Cite:	Dual-activity PI3K-BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis. Proc. Natl. Acad. Sci. U.S.A., 114, 2017

BRD4 first bromodomain (BD1) in complex with dual PI3 kinase (PI3K) inhibitor SF2535
Descriptor:	Bromodomain-containing protein 4, ethyl 4-[5-(morpholin-4-yl)-7-oxo-7H-thieno[3,2-b]pyran-3-yl]benzoate
Authors:	Andrews, F.H, Kutateladze, T.G.
Deposit date:	2016-11-30
Release date:	2017-02-08
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (1.991 Å)
Cite:	Dual-activity PI3K-BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis. Proc. Natl. Acad. Sci. U.S.A., 114, 2017