2GO5
 
 | | Structure of signal recognition particle receptor (SR) in complex with signal recognition particle (SRP) and ribosome nascent chain complex | | Descriptor: | SRP RNA, Signal recognition particle 19 kDa protein (SRP19), Signal recognition particle 54 kDa protein (SRP54), ... | | Authors: | Halic, M, Gartmann, M, Schlenker, O, Mielke, T, Pool, M.R, Sinning, I, Beckmann, R. | | Deposit date: | 2006-04-12 | | Release date: | 2006-06-13 | | Last modified: | 2011-07-13 | | Method: | ELECTRON MICROSCOPY (7.4 Å) | | Cite: | Signal Recognition Particle Receptor Exposes the Ribosomal Translocon Binding Site
Science, 312, 2006
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2PX3
 | | Crystal structure of FlhF complexed with GTP/Mg(2+) | | Descriptor: | Flagellar biosynthesis protein flhF, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | | Authors: | Bange, G, Wild, K, Sinning, I. | | Deposit date: | 2007-05-14 | | Release date: | 2007-09-25 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The crystal structure of the third signal-recognition particle GTPase FlhF reveals a homodimer with bound GTP.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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5L3W
 | | Structure of the crenarchaeal FtsY GTPase bound to GDP | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, Signal recognition particle receptor FtsY | | Authors: | Bange, G, Wild, K, Sinning, I. | | Deposit date: | 2016-05-24 | | Release date: | 2016-06-08 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex.
J.Mol.Biol., 428, 2016
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2PX0
 | | Crystal structure of FlhF complexed with GMPPNP/Mg(2+) | | Descriptor: | Flagellar biosynthesis protein flhF, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | Authors: | Bange, G, Wild, K, Sinning, I. | | Deposit date: | 2007-05-14 | | Release date: | 2007-09-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The crystal structure of the third signal-recognition particle GTPase FlhF reveals a homodimer with bound GTP.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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5L3R
 | | Structure of the GTPase heterodimer of chloroplast SRP54 and FtsY from Arabidopsis thaliana | | Descriptor: | Cell division protein FtsY homolog, chloroplastic, GLYCEROL, ... | | Authors: | Bange, G, Kribelbauer, J, Wild, K, Sinning, I. | | Deposit date: | 2016-05-24 | | Release date: | 2016-06-08 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex.
J.Mol.Biol., 428, 2016
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2Q8K
 | | The crystal structure of Ebp1 | | Descriptor: | GLYCEROL, Proliferation-associated protein 2G4, SULFATE ION | | Authors: | Kowalinski, E, Bange, G, Wild, K, Sinning, I. | | Deposit date: | 2007-06-11 | | Release date: | 2007-09-25 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The crystal structure of Ebp1 reveals a methionine aminopeptidase fold as binding platform for multiple interactions.
Febs Lett., 581, 2007
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5L3Q
 | | Structure of the GTPase heterodimer of human SRP54 and SRalpha | | Descriptor: | ADENOSINE MONOPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Wild, K, Segnitz, B, Sinning, I. | | Deposit date: | 2016-05-24 | | Release date: | 2016-06-08 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex.
J.Mol.Biol., 428, 2016
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5L3V
 | | Structure of the crenarchaeal SRP54 GTPase bound to GDP | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, Signal recognition particle 54 kDa protein | | Authors: | Bange, G, Wild, K, Sinning, I. | | Deposit date: | 2016-05-24 | | Release date: | 2016-06-08 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex.
J.Mol.Biol., 428, 2016
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5L3S
 | | Structure of the GTPase heterodimer of crenarchaeal SRP54 and FtsY | | Descriptor: | GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Bange, G, Wild, K, Sinning, I. | | Deposit date: | 2016-05-24 | | Release date: | 2016-06-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex.
J.Mol.Biol., 428, 2016
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2QY9
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4P3F
 | | Structure of the human SRP68-RBD | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Signal recognition particle subunit SRP68 | | Authors: | Grotwinkel, J.T, Wild, K, Sinning, I. | | Deposit date: | 2014-03-07 | | Release date: | 2014-04-16 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.699 Å) | | Cite: | SRP RNA remodeling by SRP68 explains its role in protein translocation.
Science, 344, 2014
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4P3E
 | | Structure of the human SRP S domain | | Descriptor: | MAGNESIUM ION, SRP RNA (124-mer), Signal recognition particle 19 kDa protein, ... | | Authors: | Grotwinkel, J.T, Wild, K, Sinning, I. | | Deposit date: | 2014-03-07 | | Release date: | 2014-04-16 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | SRP RNA remodeling by SRP68 explains its role in protein translocation.
Science, 344, 2014
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4P3G
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5M3Q
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5M43
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5MB9
 | | Crystal structure of the eukaryotic ribosome associated complex (RAC), a unique Hsp70/Hsp40 pair | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Gumiero, A, Weyer, F.A, Valentin Gese, G, Lapouge, K, Sinning, I. | | Deposit date: | 2016-11-07 | | Release date: | 2016-12-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural insights into a unique Hsp70-Hsp40 interaction in the eukaryotic ribosome-associated complex.
Nat. Struct. Mol. Biol., 24, 2017
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5M72
 | | Structure of the human SRP68-72 protein-binding domain complex | | Descriptor: | GLYCEROL, POTASSIUM ION, SULFATE ION, ... | | Authors: | Becker, M.M.M, Wild, K, Sinning, I. | | Deposit date: | 2016-10-26 | | Release date: | 2016-12-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction.
Nucleic Acids Res., 45, 2017
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5M73
 | | Structure of the human SRP S domain with SRP72 RNA-binding domain | | Descriptor: | GLYCEROL, Human gene for small cytoplasmic 7SL RNA (7L30.1), MAGNESIUM ION, ... | | Authors: | Becker, M.M.M, Wild, K, Sinning, I. | | Deposit date: | 2016-10-26 | | Release date: | 2016-12-07 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction.
Nucleic Acids Res., 45, 2017
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1JID
 | | Human SRP19 in complex with helix 6 of Human SRP RNA | | Descriptor: | HELIX 6 OF HUMAN SRP RNA, MAGNESIUM ION, SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN | | Authors: | Wild, K, Sinning, I, Cusack, S. | | Deposit date: | 2001-07-02 | | Release date: | 2001-10-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of an early protein-RNA assembly complex of the signal recognition particle.
Science, 294, 2001
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3IQX
 | | ADP complex of C.therm. Get3 in closed form | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Tail-anchored protein targeting factor Get3, ... | | Authors: | Bozkurt, G, Wild, K, Sinning, I. | | Deposit date: | 2009-08-21 | | Release date: | 2009-12-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural insights into tail-anchored protein binding and membrane insertion by Get3.
Proc.Natl.Acad.Sci.USA, 106, 2009
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3IQW
 | | AMPPNP complex of C. therm. Get3 | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Tail-anchored protein targeting factor Get3, ... | | Authors: | Bozkurt, G, Wild, K, Sinning, I. | | Deposit date: | 2009-08-21 | | Release date: | 2009-12-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural insights into tail-anchored protein binding and membrane insertion by Get3.
Proc.Natl.Acad.Sci.USA, 106, 2009
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1QZW
 | | Crystal structure of the complete core of archaeal SRP and implications for inter-domain communication | | Descriptor: | 7S RNA, Signal recognition 54 kDa protein | | Authors: | Rosendal, K.R, Wild, K, Montoya, G, Sinning, I. | | Deposit date: | 2003-09-18 | | Release date: | 2003-11-18 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (4.1 Å) | | Cite: | Crystal structure of the complete core of archaeal signal recognition particle and implications for interdomain communication
Proc.Natl.Acad.Sci.USA, 100, 2003
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1QZX
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3KTV
 | | Crystal structure of the human SRP19/S-domain SRP RNA complex | | Descriptor: | MAGNESIUM ION, POTASSIUM ION, SRP RNA, ... | | Authors: | Wild, K, Bange, G, Bozkurt, G, Sinning, I. | | Deposit date: | 2009-11-26 | | Release date: | 2010-02-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structural insights into the assembly of the human and archaeal signal recognition particles.
Acta Crystallogr.,Sect.D, 66, 2010
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3KTW
 | | Crystal structure of the SRP19/S-domain SRP RNA complex of Sulfolobus solfataricus | | Descriptor: | MAGNESIUM ION, POTASSIUM ION, SRP RNA, ... | | Authors: | Wild, K, Bange, G, Bozkurt, G, Sinning, I. | | Deposit date: | 2009-11-26 | | Release date: | 2010-02-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural insights into the assembly of the human and archaeal signal recognition particles.
Acta Crystallogr.,Sect.D, 66, 2010
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