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Structure of BACE in complex with (S)-4-(3-chloro-5-(5-(prop-1-yn-1-yl)pyridin-3-yl)thiophen-2-yl)-1,4-dimethyl-6-oxotetrahydropyrimidin-2(1H)-iminium
Descriptor:	(2Z,6S)-6-{3-chloro-5-[5-(prop-1-yn-1-yl)pyridin-3-yl]thiophen-2-yl}-2-imino-3,6-dimethyltetrahydropyrimidin-4(1H)-one, Beta-secretase 1
Authors:	Orth, P.
Deposit date:	2012-06-26
Release date:	2012-08-08
Last modified:	2013-06-19
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Discovery of an Orally Available, Brain Penetrant BACE1 Inhibitor That Affords Robust CNS A(beta) Reduction ACS Med Chem Lett, 3, 2012

Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6
Descriptor:	G25K GTP-binding protein, placental isoform, MAGNESIUM ION, ...
Authors:	Garrard, S.M, Capaldo, C.T, Gao, L, Rosen, M.K, Macara, I.G, Tomchick, D.R.
Deposit date:	2002-12-12
Release date:	2003-03-04
Last modified:	2023-08-16
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6 Embo J., 22, 2003