1R78
 
 | | CDK2 complex with a 4-alkynyl oxindole inhibitor | | 分子名称: | 4-((3R,4S,5R)-4-AMINO-3,5-DIHYDROXY-HEX-1-YNYL)-5-FLUORO-3-[1-(3-METHOXY-1H-PYRROL-2-YL)-METH-(Z)-YLIDENE]-1,3-DIHYDRO-INDOL-2-ONE, Cell division protein kinase 2 | | 著者 | Luk, K.-C, Simcox, M.E, Schutt, A, Rowan, K, Thompson, T, Chen, Y, Kammlott, U, DePinto, W, Dunten, P, Dermatakis, A. | | 登録日 | 2003-10-20 | | 公開日 | 2004-01-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A new series of potent oxindole inhibitors of CDK2
Bioorg.Med.Chem.Lett., 14, 2004
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1P2A
 | | The structure of cyclin dependent kinase 2 (CKD2) with a trisubstituted naphthostyril inhibitor | | 分子名称: | 5-[(2-AMINOETHYL)AMINO]-6-FLUORO-3-(1H-PYRROL-2-YL)BENZO[CD]INDOL-2(1H)-ONE, Cell division protein kinase 2 | | 著者 | Liu, J.-J, Dermatakis, A, Lukacs, C.M, Konzelmann, F, Chen, Y, Kammlott, U, Depinto, W, Yang, H, Yin, X, Chen, Y, Schutt, A, Simcox, M.E, Luk, K.-C. | | 登録日 | 2003-04-15 | | 公開日 | 2003-07-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | 3,5,6-Trisubstituted Naphthostyrils as CDK2 Inhibitors
BIOORG.MED.CHEM., 13, 2003
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4UII
 | | Crystal structure of the Azotobacter vinelandii globin-coupled oxygen sensor in the aquo-met form | | 分子名称: | GGDEF DOMAIN PROTEIN, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Germani, F, De Schutter, A, Pesce, A, Berghmans, H, Van Hauwaert, M.-L, Cuypers, B, Bruno, S, Mozzarelli, A, Moens, L, Van Doorslaer, S, Bolognesi, M, Nardini, M, Dewilde, S. | | 登録日 | 2015-03-30 | | 公開日 | 2016-04-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.827 Å) | | 主引用文献 | Azotobacter Vinelandii Globin-Coupled Oxygen Sensor is a Diguanylate Cyclase with a Biphasic Oxygen Dissociation
To be Published
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4UIQ
 | | Isolated globin domain of the Bordetella pertussis globin-coupled sensor with a heme at the dimer interface | | 分子名称: | GLOBIN-COUPLED SENSOR WITH DIGUANYLATE CYCLASE ACTIVITY, GLYCEROL, IMIDAZOLE, ... | | 著者 | Germani, F, Donne, J, De Schutter, A, Pesce, A, Berghmans, H, Van Hauwaert, M.-L, Moens, L, Van Doorslaer, S, Bolognesi, M, Nardini, M, Dewilde, S. | | 登録日 | 2015-03-31 | | 公開日 | 2016-04-13 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Identification of a Putative Allosteric Site in the Sensor Domain of Bordetella Pertussis Globin- Coupled Sensor for the Control of Biofilm Formation
To be Published
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6I2Z
 | | Isolated globin domain of the Bordetella pertussis globin-coupled sensor | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Uncharacterized protein | | 著者 | Germani, F, De Schutter, A, Cuypers, B, Berghmans, H, Van Hauwaert, M.-L, Bruno, S, Mozzarelli, A, Moens, L, Van Doorslaer, S, Bolognesi, M, Pesce, A, Dewilde, S. | | 登録日 | 2018-11-02 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural and Functional Characterization of the Globin-Coupled Sensors ofAzotobacter vinelandiiandBordetella pertussis.
Antioxid.Redox Signal., 32, 2020
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4J47
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4J3Y
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4J48
 | | Crystal structure of XIAP-BIR2 domain with AMRV bound | | 分子名称: | E3 ubiquitin-protein ligase XIAP, GLYCEROL, PEPTIDE (ALA-MET-ARG-VAL), ... | | 著者 | Gosu, R. | | 登録日 | 2013-02-06 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The structure of XIAP BIR2: understanding the selectivity of the BIR domains.
Acta Crystallogr.,Sect.D, 69, 2013
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4J46
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4J44
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4J45
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5A12
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5A13
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1E7W
 | | One active site, two modes of reduction correlate the mechanism of leishmania pteridine reductase with pterin metabolism and antifolate drug resistance in trpanosomes | | 分子名称: | 1,2-ETHANEDIOL, METHOTREXATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Gourley, D.G, Hunter, W.N. | | 登録日 | 2000-09-11 | | 公開日 | 2001-09-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Pteridine Reductase Mechanism Correlates Pterin Metabolism with Drug Resistance in Trypanosomatid Parasites.
Nat.Struct.Biol., 8, 2001
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